Chinese Journal of Dermatology ›› 2025, Vol. 58 ›› Issue (1): 89-92.doi: 10.35541/cjd.20240175

• Reviews • Previous Articles    

Pathogenesis and treatment of seborrheic dermatitis

Wang Di1, Zhang Ruijun2,3, Kang Yuying1   

  1. 1Department of Dermatovenereology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan 030032, China; 2Department of Dermatovenereology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan 030032, China; 3Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
  • Received:2024-04-02 Revised:2024-09-23 Online:2025-01-15 Published:2025-01-03
  • Contact: Kang Yuying E-mail:kyuying2349@163.com
  • Supported by:
    Applied Basic Research Program of Shanxi Province (201801D121292); Fundamental Research Program of Shanxi Province (202303021221196)

Abstract: 【Abstract】 Seborrheic dermatitis is a chronic, recurrent, and inflammatory skin disease. Its etiology is intricately related to skin microecological imbalance, dysregulated lipid metabolism, impaired skin barrier function, abnormal immune responses, and genetic predispositions. In recent years, several novel therapeutic approaches have emerged, such as topical phosphodiesterase 4 inhibitors, Janus kinase inhibitors, physical interventions, and chemical peeling, providing more options for the treatment of seborrheic dermatitis. This review summarizes the latest research progress in the pathogenesis and treatment of seborrheic dermatitis.

Key words: Dermatitis, seborrheic, Therapeutics, Pathogenesis, Skin microecology