中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (2): 183-186.doi: 10.35541/cjd.20200013

• 综述 • 上一篇    

2019年系统性红斑狼疮研究新进展

罗帅寒天    龙海    张桂英    陆前进   

  1. 中南大学湘雅二医院皮肤科,长沙  410011
  • 收稿日期:2020-01-03 修回日期:2020-04-29 发布日期:2021-01-29
  • 通讯作者: 陆前进 E-mail:qianlu5860@csu.edu.cn
  • 基金资助:
    国家自然科学基金(81703133、81773334);湖南省科技创新计划项目(2018RS3031);长沙市科技计划项目(KQ1802002)

Advances in systemic lupus erythematosus in 2019

Luo Shuaihantian, Long Hai, Zhang Guiying, Lu Qianjin   

  1. Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha 410011, China
  • Received:2020-01-03 Revised:2020-04-29 Published:2021-01-29
  • Contact: Lu Qianjin E-mail:qianlu5860@csu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (81703133, 81773334); Hunan Science and Technology Innovation Project (2018RS3031); Changsha Science and Technology Planning Project (KQ1802002)

摘要: 【摘要】 系统性红斑狼疮是一种主要累及中青年女性的自身免疫性疾病,临床表现复杂多样,可累及多器官系统。系统性红斑狼疮病因、诊断与治疗的研究一直是该领域的热点。2019年,国内外研究者在其发病机制、诊断和评估以及治疗方面取得了一系列新进展,本文就主要代表性成果进行综述。

关键词: 红斑狼疮, 系统性, 受体, Fc, 程序性细胞死亡受体1, 贝利尤单抗

Abstract: 【Abstract】 Systemic lupus erythematosus (SLE) is an autoimmune disease that mainly affects young and middle-aged women. It can involve multiple organ systems, with complex and diverse clinical manifestations. The research on the etiology, diagnosis and treatment of SLE has always been a hot spot in this field. In 2019, a lot of new progress was made in the pathogenesis, diagnosis and evaluation, and treatment of SLE in China and other countries, and this review summarizes main representative results.

Key words: Lupus erythematosus, systemic, Receptors, Fc, Programmed cell death 1 receptor, Belimumab