中华皮肤科杂志 ›› 2023, e20220556.doi: 10.35541/cjd.20220556
黄文华 郑振龙 金哲虎
收稿日期:2022-08-08
修回日期:2023-06-17
发布日期:2023-12-15
通讯作者:
金哲虎
E-mail:jinzh_621@163.com
基金资助:Huang Wenhua, Zheng Zhenlong, Jin Zhehu
Received:2022-08-08
Revised:2023-06-17
Published:2023-12-15
Contact:
Jin Zhehu
E-mail:jinzh_621@163.com
Supported by:摘要： 【摘要】 转化生长因子（TGF）-β/Smad通路在瘢痕疙瘩成纤维细胞的分化和瘢痕疙瘩的疾病进展中起重要作用。在瘢痕疙瘩发病过程中，缺氧诱导因子1α、微小RNA、长链非编码RNA、激活转录因子3、炎症因子、赖氨酸氧化酶样蛋白2等是TGF-β/Smad通路常见的影响因子。本文综述瘢痕疙瘩发病机制中TGF-β/Smad通路和常见影响因子的最新研究进展。
黄文华 郑振龙 金哲虎. 转化生长因子β/Smad信号通路及相关影响因子在瘢痕疙瘩中的研究进展[J]. 中华皮肤科杂志, 2023,e20220556. doi:10.35541/cjd.20220556
Huang Wenhua, Zheng Zhenlong, Jin Zhehu. Role of transforming growth factor-β/Smad pathway and related factors in the pathogenesis of keloids[J]. Chinese Journal of Dermatology,2023,e20220556. doi:10.35541/cjd.20220556
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