Chinese Journal of Dermatology ›› 2023, Vol. 56 ›› Issue (2): 177-180.doi: 10.35541/cjd.20200587

• Reviews • Previous Articles     Next Articles

Gut microbiota and immune checkpoint inhibitor treatment of melanoma

Li Tingting, Kang Xiaojing   

  1. Department of Dermatology, People′s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research(XJYS1707), Urumqi 830001, China
  • Received:2020-06-12 Revised:2020-11-15 Online:2023-02-15 Published:2023-02-01
  • Contact: Kang Xiaojing
  • Supported by:
    Autonomous Region Innovation Environment (Talent, Base) Construction Project “Tianshan Innovation Team Plan”(2020D14006)

Abstract: 【Abstract】 A growing number of studies have shown that gut microbiota affects the development of melanoma through various mechanisms, and plays a vital role in the treatment of melanoma. This review summarizes the relationship between gut microbiota and the development of melanoma, the effect of gut microbiota on the checkpoint blockade immunotherapy of melanoma and related adverse effects.

Key words: Nevi and melanomas, Metagenome, Immunotherapy, Gut microbiota, Immune checkpoint inhibitors