Chinese Journal of Dermatology ›› 2023, e20210536.doi: 10.35541/cjd.20210536

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Treatment of Merkel cell carcinoma

Yang Aimin1, Chen Jiangwei2, Huang Jiacheng1, Cen Ying3, Chen Junjie3   

  1. 1West China School of Medicine, West China Hospital, Sichuan University, Chengdu 610044, China; 2The First Hospital of China Medical University, Shenyang 110001, China; 3Department of Burns and Plastic Surgery, West China Hospital, Sichuan University, Chengdu 610044, China
  • Received:2021-07-23 Revised:2022-04-29 Online:2023-01-05 Published:2023-01-19
  • Contact: Cen Ying; Chen Junjie;
  • Supported by:
    Key Research and Development Projects of Sichuan Science and Technology Department(2020YFS0267)

Abstract: 【Abstract】 Surgical resection and radiotherapy have been frequently applied to the treatment of early- and intermediate-stage Merkel cell carcinoma. In recent years, immunotherapy based on immunogenic characteristics of Merkel cell carcinoma has been proved to be effective in the treatment of advanced Merkel cell carcinoma. This review focuses on advances in the treatment of Merkel cell carcinoma, and provides a reference for its clinical diagnosis and treatment.

Key words: Carcinoma, Merkel cell, Neuroendocrine tumor, Merkel cell polyomavirus, Immunotherapy, Immune checkpoint inhibitor