Chinese Journal of Dermatology ›› 2022, Vol. 55 ›› Issue (11): 1026-1030.doi: 10.35541/cjd.20201221

• Reviews • Previous Articles    

Cutaneous immune-related adverse reactions induced by immune checkpoint inhibitors

Zou Meirong, Wang Sheng   

  1. Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China
  • Received:2020-12-24 Revised:2021-08-18 Online:2022-11-15 Published:2022-11-03
  • Contact: Wang Sheng

Abstract: 【Abstract】 As a new type of anti-cancer drugs, immune checkpoint inhibitors have been widely used for the treatment of various tumors in recent years, but they have also caused a variety of immune-related adverse reactions, among which cutaneous adverse reactions are the most common. The onset of cutaneous adverse reactions was usually early, and most are mild, but some can also be life-threatening. This review summarizes recent advances in cutaneous immune-related adverse reactions induced by immune checkpoint inhibitors.

Key words: Drug toxicity, CTLA-4 antigen, Programmed cell death 1 receptor, Skin manifestations, Immune checkpoint inhibitors