Chinese Journal of Dermatology ›› 2025, Vol. 58 ›› Issue (1): 79-83.doi: 10.35541/cjd.20220172

• Reviews • Previous Articles     Next Articles

Biotherapy for cutaneous squamous cell carcinoma

Ji Xiang, Wang Daguang   

  1. Department of Dermatology, the First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, China
  • Received:2022-03-15 Revised:2022-08-26 Online:2025-01-15 Published:2025-01-03
  • Contact: Wang Daguang E-mail:wangirwin@126.com
  • Supported by:
    National Natural Science Foundation of China (81000703, 81472896); Natural Science Foundation of Jiangsu Province (BK2009437); Six Talent Peaks of Jiangsu Province (2015-WSW-026)

Abstract: 【Abstract】 Since cemiplimab was approved by United States Food and Drug Administration in 2018, anti-programmed cell death receptor-1 antibodies have been considered as the first-line systemic therapy for advanced cutaneous squamous cell carcinoma. This review focuses on current clinical application of targeted therapy, immunotherapy, targeted immunotherapy and gene therapy in cutaneous squamous cell carcinoma.