Abstract: 【Abstract】 Anti?p200 pemphigoid is a rare autoimmune subepidermal blistering disease characterized by diverse clinical manifestations, which can easily be confused with other autoimmune subepidermal blistering disorders. Its typical immunopathological feature is the binding of serum IgG antibodies to the dermal side of salt?split skin by indirect immunofluorescence, with circulating antibodies capable of recognizing a protein with a relative molecular mass of 200 000 in dermal extracts. This consensus covers the clinical features of, diagnostic criteria for, disease activity assessment of, therapeutic strategies for, prognosis and follow?up of anti?p200 pemphigoid, as well as dietary recommendations. Its diagnosis requires comprehensive evaluation integrating clinical manifestations, histopathological features, direct immunofluorescence and serological assays （such as indirect immunofluorescence on salt-split skin and immunoblotting）. In terms of treatment, a stepwise strategy based on disease severity is recommended, with emphasis on individualized regimens and vigilant monitoring of adverse drug reactions.

Key words: Pemphigoid, bullous, Therapeutics, Diagnosis, Practice guidelines, Anti-p200 pemphigoid, Expert consensus, Recommendation