Chinese Journal of Dermatology ›› 2026, Vol. 59 ›› Issue (4): 291-303.doi: 10.35541/cjd.20250433

• Guidelines and Consensus •     Next Articles

Expert consensus on the diagnosis and treatment of pediatric alopecia areata in China (2026 edition)

Group on Children, Chinese Society of Dermatology; Pediatric Dermatology Group, Chinese Association of Rehabilitation Dermatology; Pediatric Dermatology Group, China Dermatologist Association; External Therapy Group, Professional Committee for Children's Health and Drug Research, China Association of Traditional Chinese Medicine; Dermatology Group, China Pediatrician Association   

  1. Group on Children, Chinese Society of Dermatology; Pediatric Dermatology Group, Chinese Association of Rehabilitation Dermatology; Pediatric Dermatology Group, China Dermatologist Association; External Therapy Group, Professional Committee for Children's Health and Drug Research, China Association of Traditional Chinese Medicine; Dermatology Group, China Pediatrician Association
  • Received:2025-08-11 Revised:2026-03-05 Online:2026-04-15 Published:2026-04-03
  • Contact: Wang Hua; Ma Lin E-mail: huawang@hospital.cqmu.edu.cn; bch_maleen@ aliyun.com
  • Supported by:
    National Key Research and Development Program of China;Beijing Hospitals Authority′s Ascent Plan

Abstract: 【Abstract】 Alopecia areata is a T cell-mediated autoimmune non-scarring hair loss disorder. Its core pathogenesis involves the collapse of immune privilege in hair follicles, which subsequently triggers CD8? T cell-mediated autoimmune responses and activates multiple inflammatory pathways, including Th1, Th2, Th17, and Treg pathways. Genetic susceptibility also contributes to disease development. Pediatric alopecia areata is highly heterogeneous. Earlier age at onset, particularly before 6 years of age, is associated with greater disease severity and higher recurrence rates, leading to a more substantial impact on the quality of life of affected children and their families. Pediatric alopecia areata should be differentiated from congenital and other acquired hair loss disorders in children. Currently, the management of pediatric alopecia areata faces challenges such as age restrictions for certain treatments and limited high-level evidence-based medical data. Therefore, stratified management based on age, disease stage, and severity is recommended. Based on the latest Chinese and international clinical guidelines and research evidence, as well as key clinical questions identified using the Delphi method, an expert panel was organized to develop this consensus after systematic evaluation and discussion. This consensus provides recommendations covering clinical classification, diagnostic pathways, assessment tools, and treatment strategies, aiming to promote the standardized diagnosis and treatment of pediatric alopecia areata in China and provide guidance for clinical practice.

Key words: Alopecia areata, Children, Diagnosis, Therapy, Expert consensus