Abstract: 【Abstract】 Psoriasis is a chronic inflammatory disease with complex pathogenesis involving genetic, immune and environmental factors. Patients with psoriasis often have comorbidities related to lipid metabolism, and this correlation is based on common risk factors and pathophysiological mechanisms. This review summarizes lipid metabolism-related enzymes, receptors, and adipokines （such as proprotein convertase subtilisin/kexin type 9, secretory phospholipase A2, sortilin 1, low-density lipoprotein-related receptors 5 and 6, retinol-binding protein 4, and lipocalin-2）, which have been reported to be involved in the pathogenesis of psoriasis in recent years, aiming to provide insights into the understanding of the etiology and pathogenesis of psoriasis.

Key words: Psoriasis, Lipid metabolism disorders, Enzymes, Adipokines, Receptors, Proprotein convertase subtilisin/kexin type 9, Secretory phospholipase A2