Chinese Journal of Dermatology ›› 2022, e20220208.doi: 10.35541/cjd.20220208

• Reviews • Previous Articles    

Relationship between the pathogenesis of psoriasis and microbial flora

Xue Tianping1, Lu Zhenzhong1, Wang Hongsheng2   

  1. 1Department of Dermatology, Suzhou Wuzhong People′s Hospital, Suzhou 215128, China; 2Laboratory of Mycobacteriology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2022-03-29 Revised:2022-08-28 Online:2022-01-01 Published:2022-12-05
  • Contact: Wang Hongsheng E-mail:whs33@vip.sina.com

Abstract: 【Abstract】 Several studies have indicated that pharyngeal and intestinal microflora, as well as their metabolic products, are involved in the occurrence and development of as well as immunoregulation in psoriasis by activating T lymphocytes, dendritic cells and keratinocytes. This review summarizes current research progress in the correlation of pharyngeal and intestinal microbes with the pathogenesis of psoriasis.

Key words: Psoriasis, Nasopharynx, Gastrointestinal tract, Microbial consortia, Immunity