特异性促炎症消退介质在银屑病中的研究进展

doi:10.35541/cjd.20240503

Abstract

Abstract: 【Abstract】 Psoriasis is a chronic inflammatory skin disorder characterized by aberrant activation of T lymphocytes and excessive proliferation of keratinocytes, with persistent inflammation being the central pathological feature. Specialized pro-resolving mediators （SPMs） exert anti-inflammatory effects through various mechanisms, actively facilitating the resolution of inflammation. The dual regulatory role in inflammation has garnered attention in the study of psoriasis pathogenesis. This review aims to consolidate recent advancements in SPMs, explore their specific roles in psoriasis pathogenesis, and evaluate their potential clinical application.

Key words: Psoriasis, Fatty acids, unsaturated, Lipoxins, Specialized pro-resolving mediators, Therapy, Inflammation mediators

Huang Shudai, Zhou Xuyue, Zhang Jiaan, Chen Kun. Role of specialized pro-resolving mediators in psoriasis[J]. Chinese Journal of Dermatology,2025,e0240503. doi:10.35541/cjd.20240503

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Role of specialized pro-resolving mediators in psoriasis

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