黑素细胞及相关细胞群参与白癜风发病的研究进展

doi:10.35541/cjd.20190353

Abstract

Abstract: 【Abstract】 The pathogenesis of vitiligo is complicated, and the loss of melanocytes plays a central role. Besides deficiency in melanocytes, it is considered that dysfunction of epidermal and dermal cell populations as well as their interaction with melanocytes also play important roles in the occurrence of vitiligo, Thus, it is necessary for understanding and treatment of vitiligoto to fully and accurately understand pathophysiological states of full-thickness vitiliginous skin cells and tissues at different stages. This review aims to summarize the research progress in the role of melanocytes and related cell populations in the occurrence of vitiligo.

Key words: Vitiligo, Melanocytes, Keratinocytes, Fibroblasts, CD4-positive T-lymphocytes, CD8-positive T-lymphocytes, Memory T cells

Xu Ai′e, Zhou Miaoni, Lin Fuquan. Role of melanocytes and relevant cell populations in the occurrence of vitiligo[J]. Chinese Journal of Dermatology, 2020, 53(9): 751-754.doi:10.35541/cjd.20190353

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Role of melanocytes and relevant cell populations in the occurrence of vitiligo

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