[开放获取]    光学相干断层扫描技术在皮肤科的应用进展

doi:10.35541/cjd.20220353

Abstract

Abstract: 【Abstract】 Optical coherence tomography（OCT）is an imaging technique that obtains information in the tissue sagittal plane based on the principles of low-coherence light interference. It has characteristics of high resolution, good repeatability, rapid imaging, and non-invasiveness, and has been widely used in ophthalmology. OCT is suitable for skin imaging, and its image characteristics are highly consistent with skin structure. This review summarizes the principles of OCT and its application prospects in dermatology.

Key words: Optical devices, Diagnostic imaging, Skin diseases, Skin neoplasms, Optical coherence tomography

Hao Feng, Liu Guoyan. Application of optical coherence tomography in dermatology[J]. Chinese Journal of Dermatology,2023,e20220353. doi:10.35541/cjd.20220353

References ［35］

［1］	Schneider SL, Kohli I, Hamzavi IH, et al. Emerging imaging technologies in dermatology: part 1: basic principles［J］. J Am Acad Dermatol, 2019,80（4）:1114⁃1120. doi: 10.1016/j.jaad.2018. 11.042.
［2］	Que S. Research techniques made simple: noninvasive imaging technologies for the delineation of basal cell carcinomas［J］. J Invest Dermatol, 2016,136（4）:e33⁃e38. doi: 10.1016/j.jid.2016. 02.012.
［3］	Welzel J, Lankenau E, Birngruber R, et al. Optical coherence tomography of the human skin［J］. J Am Acad Dermatol, 1997,37（6）:958⁃963. doi: 10.1016/s0190⁃9622（97）70072⁃0.
［4］	Jerjes W, Hamdoon Z, Hopper C. Structural validation of facial skin using optical coherence tomography: a descriptive study［J］. Skin Res Technol, 2020,26（2）:153⁃162. doi: 10.1111/srt.12791.
［5］	Manfredini M, Greco M, Farnetani F, et al. Acne: morphologic and vascular study of lesions and surrounding skin by means of optical coherence tomography［J］. J Eur Acad Dermatol Venereol, 2017,31（9）:1541⁃1546. doi: 10.1111/jdv.14369.
［6］	Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography［J］. Science, 1991,254（5035）:1178⁃1181. doi: 10. 1126/science.1957169.
［7］	Wan B, Ganier C, Du⁃Harpur X, et al. Applications and future directions for optical coherence tomography in dermatology［J］. Br J Dermatol, 2021,184（6）:1014⁃1022. doi: 10.1111/bjd.19553.
［8］	Aumann S, Donner S, Fischer J, et al. Optical coherence tomography（OCT）: principle and technical realization. Cham,2019,14:59⁃85. doi: 10.1007/978⁃3⁃030⁃16638⁃0_3.
［9］	Lindert J, Tafazzoli⁃Lari K, Tüshaus L, et al. Optical coherence tomography provides an optical biopsy of burn wounds in children⁃a pilot study［J］. J Biomed Opt, 2018,23（10）:1⁃6. doi: 10.1117/1.JBO.23.10.106005.
［10］	Ulrich M, Themstrup L, de Carvalho N, et al. Dynamic optical coherence tomography in dermatology［J］. Dermatology, 2016,232（3）:298⁃311. doi: 10.1159/000444706.
［11］	Kirby MA, Pelivanov I, Song S, et al. Optical coherence elastography in ophthalmology［J］. J Biomed Opt, 2017,22（12）:1⁃28. doi: 10.1117/1.JBO.22.12.121720.
［12］	Ruini C, Schuh S, Sattler E, et al. Line⁃field confocal optical coherence tomography⁃practical applications in dermatology and comparison with established imaging methods［J］. Skin Res Technol, 2021,27（3）:340⁃352. doi: 10.1111/srt.12949.
［13］	Calvo⁃Sanz JA, Ruiz⁃Alcocer J, Sánchez⁃Tena MA. Accuracy of Cirrus HD⁃OCT and Topcon SP⁃3000P for measuring central corneal thickness［J］. J Optom, 2018,11（3）:192⁃197. doi: 10. 1016/j.optom.2016.12.004.
［14］	Mogensen M, Morsy HA, Thrane L, et al. Morphology and epidermal thickness of normal skin imaged by optical coherence tomography［J］. Dermatology, 2008,217（1）:14⁃20. doi: 10.1159/000118508.
［15］	Lindsø Andersen P, Olsen J, Friis K, et al. Vascular morphology in normal skin studied with dynamic optical coherence tomography［J］. Exp Dermatol, 2018,27（9）:966⁃972. doi: 10. 1111/exd.13680.
［16］	Holmes J, von Braunmühl T, Berking C, et al. Optical coherence tomography of basal cell carcinoma: influence of location, subtype, observer variability and image quality on diagnostic performance［J］. Br J Dermatol, 2018,178（5）:1102⁃1110. doi: 10.1111/bjd.16154.
［17］	Cinotti E, Tognetti L, Cartocci A, et al. Line⁃field confocal optical coherence tomography for actinic keratosis and squamous cell carcinoma: a descriptive study［J］. Clin Exp Dermatol, 2021,46（8）:1530⁃1541. doi: 10.1111/ced.14801.
［18］	Gaitanis G, Tsironi T, Spyridonos P, et al. A case series of Bowen′s disease treated with the combination of cryosurgery and ingenol mebutate and followed up with optical coherence tomography［J］. Case Rep Dermatol Med, 2018,2018:9423949. doi: 10.1155/2018/9423949.
［19］	Ulrich M, Themstrup L, de Carvalho N, et al. Dynamic optical coherence tomography of skin blood vessels ⁃ proposed terminology and practical guidelines［J］. J Eur Acad Dermatol Venereol, 2018,32（1）:152⁃155. doi: 10.1111/jdv.14508.
［20］	Themstrup L, De Carvalho N, Nielsen SM, et al. In vivo differentiation of common basal cell carcinoma subtypes by microvascular and structural imaging using dynamic optical coherence tomography［J］. Exp Dermatol, 2018,27（2）:156⁃165. doi: 10.1111/exd.13479.
［21］	Reddy N, Nguyen BT. The utility of optical coherence tomography for diagnosis of basal cell carcinoma: a quantitative review［J］. Br J Dermatol, 2019,180（3）:475⁃483. doi: 10.1111/bjd.17201.
［22］	Olsen J, Themstrup L, De Carvalho N, et al. Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma［J］. Photodiagnosis Photodyn Ther, 2016,16:44⁃49. doi: 10.1016/j.pdpdt.2016.08.004.
［23］	Ulrich M, von Braunmuehl T, Kurzen H, et al. The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of nonpigmented basal cell carcinoma: an observational study［J］. Br J Dermatol, 2015,173（2）:428⁃435. doi: 10.1111/bjd.13853.
［24］	Jerjes W, Hamdoon Z, Al⁃Rawi N, et al. Optical coherence tomography in the assessment of cutaneous cancer margins of the face: an immediate ex vivo study［J］. Photodiagnosis Photodyn Ther, 2020,29:101616. doi: 10.1016/j.pdpdt.2019.101616.
［25］	De Carvalho N, Schuh S, Kindermann N, et al. Optical coherence tomography for margin definition of basal cell carcinoma before micrographic surgery⁃recommendations regarding the marking and scanning technique［J］. Skin Res Technol, 2018,24（1）:145⁃151. doi: 10.1111/srt.12407.
［26］	Gambichler T, Plura I, Schmid⁃Wendtner M, et al. High⁃definition optical coherence tomography of melanocytic skin lesions［J］. J Biophotonics, 2015,8（8）:681⁃686. doi: 10.1002/jbio.201400085.
［27］	Welzel J, Schuh S, De Carvalho N, et al. Dynamic optical coherence tomography shows characteristic alterations of blood vessels in malignant melanoma［J］. J Eur Acad Dermatol Venereol, 2021,35（5）:1087⁃1093. doi: 10.1111/jdv.17080.
［28］	Trojahn C, Dobos G, Richter C, et al. Measuring skin aging using optical coherence tomography in vivo: a validation study［J］. J Biomed Opt, 2015,20（4）:045003. doi: 10.1117/1.JBO.20.4.045003.
［29］	Mandel VD, Cinotti E, Benati E, et al. Reflectance confocal microscopy and optical coherence tomography for the diagnosis of bullous pemphigoid and pemphigus and surrounding subclinical lesions［J］. J Eur Acad Dermatol Venereol, 2018,32（9）:1562⁃1569. doi: 10.1111/jdv.14795.
［30］	Ring C, Cox N, Lee JB. Dermatoscopy［J］. Clin Dermatol, 2021,39（4）:635⁃642. doi: 10.1016/j.clindermatol.2021.03.009.
［31］	Hobelsberger S, Laske J, Aschoff R, et al. Examination of subungual hematomas and subungual melanocytic lesions by using optical coherence tomography and dermoscopy［J］. Dermatology, 2022,238（6）:1130⁃1138. doi: 10.1159/000524347.
［32］	Lu Q, Jiang G. Progress in the application of reflectance confocal microscopy in dermatology［J］. Postepy Dermatol Alergol, 2021,38（5）:709⁃715. doi: 10.5114/ada.2021.110077.
［33］	Aleissa S, Navarrete⁃Dechent C, Cordova M, et al. Presurgical evaluation of basal cell carcinoma using combined reflectance confocal microscopy⁃optical coherence tomography: a prospective study［J］. J Am Acad Dermatol, 2020,82（4）:962⁃968. doi: 10. 1016/j.jaad.2019.10.028.
［34］	Polańska A, Dańczak⁃Pazdrowska A, Jałowska M, et al. Current applications of high⁃frequency ultrasonography in dermatology［J］. Postepy Dermatol Alergol, 2017,34（6）:535⁃542. doi: 10. 5114/ada.2017.72457.
［35］	Barcaui EO, Carvalho A, Valiante PM, et al. High⁃frequency（22⁃MHz） ultrasound for assessing the depth of basal cell carcinoma invasion［J］. Skin Res Technol, 2021,27（5）:676⁃681. doi: 10.1111/srt.12999.

[1]	Hong Yongzhen, Wang Qian, Liang Junqin, . Application of next-generation sequencing in the field of non-hereditary dermatoses [J]. Chinese Journal of Dermatology, 2024, 0(3): 20220436-e20220436.
[2]	Guo Lei, Cao Chunyan, Fang Xiaoya, Feng Suying. Analysis of current status and risk factors of multidrug-resistant bacteria wound infections in patients with autoimmune bullous diseases [J]. Chinese Journal of Dermatology, 2024, 57(2): 155-160.
[3]	Yue Chao, Duan Mengying, Wang Tao, Zhang Manyu, Dai Yeqin, Peng Jianzhong, Song Xiuzu. Application of the upper eyelid orbicularis oculi myocutaneous island flap in repairing secondary defects after resection of eyelid and periorbital skin tumors: a retrospective analysis of 28 cases [J]. Chinese Journal of Dermatology, 2023, 56(9): 862-865.
[4]	Jing Ke, Wang Yuan, Li Suo, Feng Suying. Autoimmune subepidermal bullous diseases characterized by annular erythema and blisters: a retrospective analysis of 25 cases [J]. Chinese Journal of Dermatology, 2023, 56(9): 832-838.
[5]	Chen Yaolong, Liu Hui, Yao Zhirong, Gao Xinghua. Strategies and suggestions for improving the quality of guidelines and consensus in the field of dermatology [J]. Chinese Journal of Dermatology, 2023, 56(9): 805-808.
[6]	Sun Xiaojie, Liu Yi. Anti-androgen drugs in the treatment of skin diseases [J]. Chinese Journal of Dermatology, 2023, 56(9): 882-885.
[7]	Wang Xiaoyan, Zhang Jiawen, Liu Yunyi, Liu Yixuan, Jiang Peiyu, Li Min, Tao Meng, Xu Yang. Skin imaging and noninvasive measurements of rosacea [J]. Chinese Journal of Dermatology, 2023, 56(4): 361-364.
[8]	Lian Panpan, Liu Jun, Su Zhonglan, Wang Hongwei. Effect of peroxisome proliferator-activated receptor γ on skin physiological and pathological processes [J]. Chinese Journal of Dermatology, 2023, 56(4): 365-368.
[9]	Xie yuanyuan, Liu Yuzhen, Zeng Rong, . Application of skin imaging techniques in acne vulgaris [J]. Chinese Journal of Dermatology, 2023, 0(2): 20230100-e20230100.
[10]	Huang Shudai, Wang Daguang. Skin imaging techniques for nails and nail diseases [J]. Chinese Journal of Dermatology, 2023, 0(2): 20210820-e20210820.
[11]	Zheng Nana, Zeng Rong, Tao Yingkai, Li Min, . Relationship between circular RNAs and skin tumors [J]. Chinese Journal of Dermatology, 2023, 0(2): 20210893-e20210893.
[12]	Zhang Jiaqi, Wu Fan, Han Yuqing, Liu Qi, Pan Yao. Application of multi-photon microscopy in dermatology [J]. Chinese Journal of Dermatology, 2023, 0(2): 20230022-e20230022.
[13]	Yang Xiaoli, Deng Danqi. Periodontitis and immune skin diseases [J]. Chinese Journal of Dermatology, 2023, 0(2): 20230059-e20230059.
[14]	Liu Lihao, Hu Yu, Chen Kun. Clinical application and development of photobiomodulation in dermatology [J]. Chinese Journal of Dermatology, 2023, 0(2): 20230312-e20230312.
[15]	Jiang Jiayi, Wang Daguang. Prevention and management of thrombus during the perioperative period after dermatologic surgery [J]. Chinese Journal of Dermatology, 2023, 0(2): 20220147-e0220147.

Application of optical coherence tomography in dermatology

PDF

PDF (Mobile)

Knowledge

Abstract

Cite this article

share this article

References ［35］

Related Articles 15

Metrics

Comments

Recommended 10