[开放获取]    超声检查在皮肤科的应用前景

doi:10.35541/cjd.20240212

Abstract

Abstract: 【Abstract】 In recent years, ultrasonography has been more and more widely applied in the diagnosis and treatment of skin diseases, as well as in the field of aesthetic dermatology. Compared with physical examination, ultrasonography can more intuitively reflect the normal structures of skin soft tissues, and be used to more objectively assess deeper skin lesions, showing great application prospects in dermatology. This article provides an overview of the advances in the application of ultrasonography in the field of dermatology.

Key words: Ultrasonography, High-frequency ultrasound, Skin diseases, Diagnosis, Diagnosis, differential, Efficacy evaluation

Zou Xianbiao, Chen Jinchun, Zeng Yue, Hao Yi. Application of ultrasonography in dermatology: progress and prospects[J]. Chinese Journal of Dermatology, 2024, 57(9): 785-790.doi:10.35541/cjd.20240212

References ［57］

［1］	Wang S, Yu RX, Fan W, et al. Detection of skin thickness and density in healthy Chinese people by using high⁃frequency ultrasound［J］. Skin Res Technol, 2023,29（1）:e13219. doi: 10.1111/srt.13219.
［2］	于瑞星, 薛珂, 沈雪, 等. 高频超声检测健康成人皮肤厚度及回声密度［J］. 中华皮肤科杂志, 2019,52（6）:414⁃419. doi: 10.3760/cma.j.issn.0412⁃4030.2019.06.008.
［3］	Bellinato F, Gisondi P, Filippucci E, et al. Systematic study on nail plate assessment: differences in nail plate shape, thickness, power Doppler signal and scanning approach［J］. Arch Dermatol Res, 2023,315（3）:593⁃600. doi: 10.1007/s00403⁃022⁃02404⁃5.
［4］	Guazzaroni M, Ferrari D, Lamacchia F, et al. Shear wave elastography and microvascular ultrasound in response evaluation to calcipotriol+betamethasone foam in plaque psoriasis［J］. Postgrad Med J, 2021,97（1143）:16⁃22. doi: 10.1136/postgradmedj⁃2020⁃138150.
［5］	Chen ZT, Chen RF, Li XL, et al. The role of ultrasound in screening subclinical psoriatic arthritis in patients with moderate to severe psoriasis［J］. Eur Radiol, 2023,33（6）:3943⁃3953. doi: 10.1007/s00330⁃023⁃09493⁃4.
［6］	Yamada Y, Inui K, Okano T, et al. Ultrasound assessment, unlike clinical assessment, reflects enthesitis in patients with psoriatic arthritis［J］. Clin Exp Rheumatol, 2021,39（1）:139⁃145. doi: 10.55563/clinexprheumatol/u8qc6c.
［7］	Norden A, Oulee A, Ivanic M, et al. The use of ultrasound to detect enthesitis as a potential guide for intervention in patients with psoriasis at risk of psoriatic arthritis: a systematic review［J］. Int J Dermatol, 2023,62（8）:973⁃979. doi: 10.1111/ijd.16645.
［8］	Acosta⁃Felquer ML, Ruta S, Rosa J, et al. Ultrasound entheseal abnormalities at the distal interphalangeal joints and clinical nail involvement in patients with psoriasis and psoriatic arthritis, supporting the nail⁃enthesitis theory［J］. Semin Arthritis Rheum, 2017,47（3）:338⁃342. doi: 10.1016/j.semarthrit.2017.05.002.
［9］	Crisan D, Weins AB, Strilciuc S, et al. The sonographic resistivity index: a non⁃invasive parameter for therapeutic efficacy assessment in psoriatic onychopathy［J］. Int J Dermatol, 2022,61（10）:e368⁃e370. doi: 10.1111/ijd.16294.
［10］	De Rossi SD, Mendonça JA, Palominos PE, et al. Ultrasonographic and resistance index evaluation of nails in psoriatic arthritis, psoriasis, and control groups: a cross⁃sectional study［J］. Adv Rheumatol, 2021,61（1）:48. doi: 10.1186/s42358⁃021⁃00207⁃2.
［11］	Muñoz⁃Santos C, Sola⁃Ortigosa J, Vidal D, et al. Apremilast improves quality of life and ultrasonography parameters in patients with nail psoriasis: a prospective cohort study［J］. J Dermatol, 2021,48（10）:1593⁃1596. doi: 10.1111/1346⁃8138.16074.
［12］	Niu Z, Wang Y, Zhu Q, et al. The value of high⁃frequency ultrasonography in the differential diagnosis of early mycosis fungoides and inflammatory skin diseases: a case⁃control study［J］. Skin Res Technol, 2021,27（3）:453⁃460. doi: 10.1111/srt.12945.
［13］	Zheng X, Wu C, Jin H, et al. Investigation of using very high⁃frequency ultrasound in the differential diagnosis of early⁃stage pemphigus vulgaris vs seborrheic dermatitis［J］. Skin Res Technol, 2020,26（4）:476⁃481. doi: 10.1111/srt.12836.
［14］	靳诗颖, 史进军, 高启, 等. 高频超声辅助评估丹毒治疗效果的前瞻性对照研究［J］. 中华皮肤科杂志, 2023,56（5）:434⁃438. doi: 10.35541/cjd.20220337.
［15］	范文葛, 张青松, 叶迅, 等. 男性阴茎附属腺和皮肤淋球菌感染皮损的高频超声研究［J］. 中华皮肤科杂志, 2022,55（6）:528⁃531. doi: 10.35541/cjd.20210278.
［16］	Wang X, Zhao Q, Li J, et al. Evaluation of early manifestations of spreading pattern Mycobacterium marinum infection by ultrasonography［J］. Skin Res Technol, 2022,28（3）:489⁃490. doi: 10.1111/srt.13147.
［17］	Luppi AM, Ferreira GE, Prudêncio DL, et al. High⁃resolution ultrasonography for early diagnosis of neural impairment in seropositive leprosy household contacts［J/OL］. PLoS One, 2023,18（5）:e0285450. doi: 10.1371/journal.pone.0285450.
［18］	Lugão HB, Savarese LG, Silva S, et al. Methylprednisolone pulse therapy for leprosy neuritis: a retrospective study with sensory testing and peripheral nerve ultrasonography correlation［J］. Indian J Dermatol Venereol Leprol, 2021,88（1）:114⁃116. doi: 10.25259/IJDVL_1280_20.
［19］	Ogueta I, Navajas⁃Galimany L, Concha⁃Rogazy M, et al. Very high⁃ and high⁃frequency ultrasound features of cutaneous larva migrans［J］. J Ultrasound Med, 2019,38（12）:3349⁃3358. doi: 10.1002/jum.15023.
［20］	Saavedra AC, Valencia BM, Tueros P, et al. Ultrasonographic characteristics of cutaneous leishmaniasis［J］. J Eur Acad Dermatol Venereol, 2020,34（4）:e193⁃e195. doi: 10.1111/jdv. 16111.
［21］	Izzetti R, Nisi M, Aringhieri G, et al. Ultra⁃high frequency ultrasound in the differential diagnosis of oral pemphigus and pemphigoid: an explorative study［J］. Skin Res Technol, 2021,27（5）:682⁃691. doi: 10.1111/srt.13000.
［22］	Wang X, Sun J. High⁃frequency ultrasound features of pemphigoid nodularis: a case report［J］. Skin Res Technol, 2022,28（1）:171⁃172. doi: 10.1111/srt.13077.
［23］	Pu Y, Zhang L. Application of dermatoscopy, reflectance confocal microscopy, and high⁃frequency ultrasound for diagnosing neonatal lupus erythematosus: a case report［J］. Skin Res Technol, 2023,29（2）:e13291. doi: 10.1111/srt.13291.
［24］	Giavedoni P, Podlipnik S, Fuertes de Vega I, et al. High⁃frequency ultrasound to assess activity in connective tissue panniculitis［J］. J Clin Med, 2021,10（19）:4516. doi: 10.3390/jcm10194516.
［25］	柴可, 喻江帆, 林彩虹, 等. 基于高频超声的局限性硬皮病皮损分期预测模型的建立及验证［J］. 中华皮肤科杂志, 2023,56（11）:1008⁃1015. doi: 10.35541/cjd.20220813.
［26］	Khorasanizadeh F, Kalantari Y, Etesami I. Role of imaging in morphea assessment: a review of the literature［J］. Skin Res Technol, 2023,29（7）:e13410. doi: 10.1111/srt.13410.
［27］	Wortsman X, Vera⁃Kellet C. Ultrasound morphea activity scoring （US⁃MAS）: modified US⁃MAS［J］. J Ultrasound Med, 2023,42（10）:2447⁃2450. doi: 10.1002/jum.16247.
［28］	Cardones AR, Hall RP 3rd, Sullivan KM, et al. Quantifying skin stiffness in graft⁃versus⁃host disease, morphea, and systemic sclerosis using acoustic radiation force impulse imaging and shear wave elastography［J］. J Invest Dermatol, 2021,141（4）:924⁃927.e2. doi: 10.1016/j.jid.2020.07.031.
［29］	Juan⁃Carpena G, Palazón⁃Cabanes JC, Tallón⁃Guerola P, et al. A case series of 18 congenital haemangiomas: clinical, histological and ultrasound features, and their relationship with complications and atypical behaviour［J］. Acta Derm Venereol, 2023,103:adv00849. doi: 10.2340/actadv.v103.3983.
［30］	Iznardo H, Vilarrasa E, Roé E, et al. Shear wave elastography as a potential tool for quantitative assessment of sinus tracts fibrosis in hidradenitis suppurativa［J］. J Eur Acad Dermatol Venereol, 2022,36（8）:e652⁃e654. doi: 10.1111/jdv.18116.
［31］	盛珉旻, 王芳, 张汝芝, 等. 海姆泊芬光动力治疗鲜红斑痣的临床疗效及声像学变化研究［J］. 中华皮肤科杂志, 2019,52（12）:923⁃927. doi: 10.35541/cjd.20180737.
［32］	Esposito F, Ferrara D, Di Serafino M, et al. Classification and ultrasound findings of vascular anomalies in pediatric age: the essential［J］. J Ultrasound, 2019,22（1）:13⁃25. doi: 10.1007/s40477⁃018⁃0342⁃1.
［33］	García⁃Martínez FJ, de Cabo Francés F. Contrast⁃enhanced ultrasound with peroxide hydrogen for hidradenitis suppurativa and pilonidal sinus presurgical mapping［J］. J Am Acad Dermatol, 2023,88（4）:e163⁃e164. doi: 10.1016/j.jaad.2020.12.074.
［34］	Der Sarkissian S, Frew JW. Ultrasound⁃guided de⁃roofing of epithelialised tunnels of hidradenitis suppurativa［J］. Australas J Dermatol, 2021,62（3）:360⁃363. doi: 10.1111/ajd.13600.
［35］	Wang J, Luo Y, Liu J, et al. High⁃frequency ultrasonography and scoring of acne at 20 and 50 MHz［J］. J Eur Acad Dermatol Venereol, 2020,34（11）:e743⁃e745. doi: 10.1111/jdv.16584.
［36］	米淑宏, 余艳琴, 郝金奇, 等. 丘疹脓疱型玫瑰痤疮患者皮肤高频超声联合彩色多普勒血流成像的特征［J］. 中华皮肤科杂志, 2023,56（6）:540⁃544. doi: 10.35541/cjd.20220807.
［37］	Ten B, Kaya Tİ, Balcı Y, et al. The place of B⁃mode ultrasonography, shear⁃wave elastography, and superb microvascular imaging in the pre⁃diagnosis of androgenetic alopecia［J］. J Cosmet Dermatol, 2022,21（7）:2962⁃2970. doi: 10.1111/jocd.14488.
［38］	Porriño⁃Bustamante ML, Fernández⁃Pugnaire MA, Castellote⁃Caballero L, et al. Colour Doppler ultrasound study in patients with frontal fibrosing alopecia［J］. Skin Res Technol, 2021,27（5）:709⁃714. doi: 10.1111/srt.13004.
［39］	钟琳, 唐远姣, 杨裕佳, 等. 高频彩色多普勒超声对皮肤实性肿瘤诊断价值的初步研究［J］. 四川大学学报（医学版）, 2017,48（1）:111⁃115. doi: 10.13464/j.scuxbyxb.2017.01.023.
［40］	Wang YK, Gao YJ, Liu J, et al. A comparative study of melanocytic nevi classification with dermoscopy and high⁃frequency ultrasound［J］. Skin Res Technol, 2022,28（2）:265⁃273. doi: 10.1111/srt.13123.
［41］	Wortsman X, Ferreira⁃Wortsman C, Corredoira Y. Ultrasound imaging of nevus sebaceous of Jadassohn［J］. J Ultrasound Med, 2021,40（2）:407⁃415. doi: 10.1002/jum.15405.
［42］	中华医学会超声医学分会浅表器官及血管学组, 中国中西医结合学会皮肤性病专业委员会, 上海超声诊疗工程技术研究中心, 等. 皮肤疾病超声检查指南（2022版）［J］. 中华超声影像学杂志, 2022,31（7）:553⁃578. doi:10.3760/cma.j.cn131148⁃20220408⁃00245.
［43］	陈美卿, 邱晓燕, 邱洋洋, 等. 毛母质瘤的临床、超声、皮肤镜特征［J］. 中国临床医学, 2023,30（3）:495⁃501. doi: 10.12025/j.issn.1008⁃6358.2023.20221663
［44］	Liang JF, Feng MC, Luo PP, et al. High⁃frequency ultrasound and shear wave elastography in quantitative differential diagnosis of high⁃risk and low⁃risk basal cell carcinomas［J］. J Ultrasound Med, 2022,41（6）:1447⁃1454. doi: 10.1002/jum.15829.
［45］	Reginelli A, Russo A, Berritto D, et al. Ultra⁃high⁃frequency ultrasound: a modern diagnostic technique for studying melanoma［J］. Ultraschall Med, 2023,44（4）:360⁃378. doi: 10.1055/a⁃2028⁃6182.
［46］	Chauvel⁃Picard J, Tognetti L, Cinotti E, et al. Role of ultra⁃high⁃frequency ultrasound in the diagnosis and management of basal cell carcinoma: pilot study based on 117 cases［J］. Clin Exp Dermatol, 2023,48（5）:468⁃475. doi: 10.1093/ced/llad001.
［47］	梁键锋, 冯明初, 罗平平, 等. 高频超声和剪切波弹性成像在基底细胞癌术前评估中的应用［J］. 中华皮肤科杂志, 2021,54（11）:961⁃965. doi: 10.35541/cjd.20210125.
［48］	王诗琪, 刘洁, 朱庆莉, 等. 皮肤高频超声和皮肤镜在基底细胞癌术前精确评估中的应用［J］. 中华皮肤科杂志, 2020,53（1）:51⁃55. doi: 10.35541/cjd.20190243.
［49］	Li MX, Wang Q, Li XL, et al. Imaging findings of Bowen's disease: a comparison between ultrasound biomicroscopy and conventional high⁃frequency ultrasound［J］. Skin Res Technol, 2020,26（5）:654⁃663. doi: 10.1111/srt.12849.
［50］	张磊, 尹盼盼, 周亚丽, 等. 乳房外Paget病的高频彩色多普勒超声特征分析［J］. 中华皮肤科杂志, 2021,54（7）:625⁃628. doi:10.35541/cjd.20200425.
［51］	李峰, 郑晓枫, 乔菊, 等. A型肉毒毒素注射治疗眉间纹的高频超声研究［J］. 中华皮肤科杂志, 2020,53（3）:223⁃225. doi: 10.35541/cjd.20190272.
［52］	Czajkowska J, Juszczyk J, Bugdol MN, et al. High⁃frequency ultrasound in anti⁃aging skin therapy monitoring［J］. Sci Rep, 2023,13（1）:17799. doi: 10.1038/s41598⁃023⁃45126⁃y.
［53］	王冬梅, 向茜, 杨裕佳. 剪切波弹性成像用于皮肤疾病研究进展［J］. 中国医学影像技术, 2023,39（5）:781⁃784. doi: 10. 13929/j.issn.1003⁃3289.2023.05.033.
［54］	赵海娜, 骆洪浩, 彭玉兰. 隆突性皮肤纤维肉瘤的高频超声表现［J］. 临床超声医学杂志, 2016,18（6）:412⁃414. doi: 10. 16245/j.cnki.issn1008⁃6978.2016.06.020.
［55］	Feng X, Li GY, Ramier A, et al. In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh⁃wave optical coherence elastography［J］. Acta Biomater, 2022,146:295⁃305. doi: 10.1016/j.actbio.2022.04.030.
［56］	Corvino A, Varelli C, Cocco G, et al. Seeing the unseen with superb microvascular imaging: ultrasound depiction of normal dermis vessels［J］. J Clin Ultrasound, 2022,50（1）:121⁃127. doi: 10.1002/jcu.23068.
［57］	Czajkowska J, Borak M. Computer⁃aided diagnosis methods for high⁃frequency ultrasound data analysis: a review［J］. Sensors （Basel）, 2022,22（21）:8326. doi: 10.3390/s22218326.

[1]	Lu Qing, Liu Yanqiu, Liu Danping, Zou Yongyi, Yang Bicheng. Variation analysis and prenatal diagnosis in a pedigree with oculocutaneous albinism [J]. Chinese Journal of Dermatology, 2024, 57(9): 842-843.
[2]	Hao Feng, Liu Guoyan. Application of optical coherence tomography in dermatology [J]. Chinese Journal of Dermatology, 2024, 57(9): 853-857.
[3]	Huang Shudai, Wang Daguang. Skin imaging techniques for nails and nail diseases [J]. Chinese Journal of Dermatology, 2024, 57(9): 866-869.
[4]	Xiang Xi, Zhang Lingyan, Zhong Lin, Gao Yi, Qiu Li. Multimodal ultrasound manifestations of port-wine stains and their application in efficacy assessment of photodynamic therapy [J]. Chinese Journal of Dermatology, 2024, 57(9): 801-806.
[5]	Zeng Yue, Shao Huihong, Lin Shiwen, Wen Rou, Zou Xianbiao. Application of a wearable teleconsultation device in diagnosis of common skin diseases [J]. Chinese Journal of Dermatology, 2024, 57(9): 797-800.
[6]	He Lan, Ma Ling, Jiang Qian, Chen Liuqing, Chen Hongying. Analysis of dermoscopic and reflectance confocal microscopic characteristics of 57 cases of extragenital lichen sclerosus [J]. Chinese Journal of Dermatology, 2024, 57(9): 791-796.
[7]	Combination of Traditional and Western Medicine Dermatology, Chinese Society of Dermatology, China Dermatologist Association. Expert consensus on the application of reflectance confocal microscopy in common melanocytic skin tumors（2024） [J]. Chinese Journal of Dermatology, 2024, 57(9): 775-784.
[8]	Zhang Jiaqi, Wu Fan, Han Yuqing, Liu Qi, Pan Yao. Application of multi-photon microscopy in dermatology [J]. Chinese Journal of Dermatology, 2024, 57(9): 857-862.
[9]	Zuo Mo, Liu Guoyan. Application of skin imaging techniques in determining surgical margins of basal cell carcinoma [J]. Chinese Journal of Dermatology, 2024, 57(9): 850-852.
[10]	Zhang Rongju, Zhu Yueqian, Zhou Naihui, Qian Qihong. Imaging techniques in keloids [J]. Chinese Journal of Dermatology, 2024, 57(9): 846-849.
[11]	Xie yuanyuan, Liu Yuzhen, Zeng Rong, . Application of skin imaging techniques in acne vulgaris [J]. Chinese Journal of Dermatology, 2024, 57(8): 757-760.
[12]	Liu Qingfeng, Liu Lian, Diao Ping, Li Xiaoxue, Zhang Ting, Chen Haotian, Liu Xu, Jiang Xian. Diagnosis and treatment of port-wine stains-associated syndromes [J]. Chinese Journal of Dermatology, 2024, 57(7): 656-660.
[13]	Jing Ke, Li Suo, Feng Suying. Clinical and immunoserological characteristics of 26 cases of linear IgA bullous dermatosis: a retrospective analysis [J]. Chinese Journal of Dermatology, 2024, 57(6): 503-509.
[14]	Han Yan, Xu Peng, Xiang Zhi, Jiang Tingting, Ge Fengqin, Yin Yueping, Chen Xiangsheng, . Strengthening research on prevention and treatment of chronic skin diseases — population medicine research program [J]. Chinese Journal of Dermatology, 2024, 57(6): 567-569.
[15]	aser Cosmetology Group, Medical Aesthetics and Cosmetology Branch of Chinese Medical Association, Skin Care Product and Material Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment, Laser Group, Cosmetic and Plastic Surgeon Branch of Chinese Medical Doctor Association, Cosmetic Laser Group, Chinese Society of Dermatology. Guidelines for the diagnosis and treatment of adverse skin reactions to cosmetics （2024 edition） [J]. Chinese Journal of Dermatology, 2024, 57(6): 485-492.

Application of ultrasonography in dermatology: progress and prospects

PDF

Knowledge

Abstract

Cite this article

share this article

References ［57］

Related Articles 15

Metrics

Comments

Recommended 10