Chinese Journal of Dermatology ›› 2021, Vol. 54 ›› Issue (2): 116-121.doi: 10.35541/cjd.20200469

• Expert Commentary • Previous Articles     Next Articles

Azathioprine in the treatment of immune?related skin diseases: an expert proposal

Committee on Autoimmune Diseases, China Dermatologist Association   

  1. Committee on Autoimmune Diseases, China Dermatologist Association
  • Received:2020-05-14 Revised:2020-08-24 Online:2021-02-15 Published:2021-01-29
  • Contact: Deng Danqi

Abstract: 【Abstract】 Azathioprine, an imidazole derivative of mercaptopurine, has been widely used in the treatment of autoimmune diseases. In order to standardize the application of azathioprine in dermatology, relevant experts in the Committee on Autoimmune Diseases of China Dermatologist Association searched and studied domestic and foreign literature on azathioprine for the treatment of immune-related diseases (mainly including randomized control trials, expert consensus or proposals), and proposed a proposal after repeated discussions for azathioprine in the treatment of immune skin diseases, including immune bullous skin diseases, cutaneous vasculitis, systemic lupus erythematosus, dermatomyositis, scleroderma, etc. Interactions between azathioprine and other drugs, as well as issues needed to be considered in its application were also analyzed in this proposal.

Key words: Azathioprine, Therapy, Autoimmune diseases, Connective tissue diseases, Pemphigus, Lupus erythematosus, systemic, Dermatomyositis