Chinese Journal of Dermatology ›› 2024, e0230274.doi: 10.35541/cjd.20230274
• Reviews • Previous Articles Next Articles
Dai Yeqin1,2, Song Xiuzu2
Received:
2023-05-15
Revised:
2023-07-04
Online:
2024-01-29
Published:
2024-01-29
Contact:
Song Xiuzu
E-mail:songxiuzu@sina.com.cn
Supported by:
Dai Yeqin, Song Xiuzu. Application of hair follicle transplantation and follicular cell suspension transplantation in the treatment of vitiligo[J]. Chinese Journal of Dermatology,2024,e0230274. doi:10.35541/cjd.20230274
[1] | Erdoğan A, Mutlu HS, Solakoğlu S. Autologously transplanted dermis⁃derived cells alleviated monobenzone⁃induced vitiligo in mouse[J]. Exp Dermatol, 2022,31(9):1355⁃1363. doi: 10.1111/exd.14603. |
[2] | Ghasemi M, Bajouri A, Shafiiyan S, et al. Hair follicle as a source of pigment⁃producing cells for treatment of vitiligo: an alternative to epidermis?[J]. Tissue Eng Regen Med, 2020,17(6):815⁃827. doi: 10.1007/s13770⁃020⁃00284⁃2. |
[3] | Kerure AS, Deshmukh N, Agrawal S, et al. Follicular unit extraction [FUE] ⁃ one procedure, many uses[J]. Indian Dermatol Online J, 2021,12(3):381⁃388. doi: 10.4103/idoj.IDOJ_522_20. |
[4] | Dhar S, Sawhney A, Ralli M. Maxillofacial surgery and hair transplantation: ethics with expertise[J]. J Maxillofac Oral Surg, 2023,22(1):67⁃74. doi: 10.1007/s12663⁃020⁃01479⁃9. |
[5] | Tobin DJ. Human hair pigmentation⁃⁃biological aspects[J]. Int J Cosmet Sci, 2008,30(4):233⁃257. doi: 10.1111/j.1468⁃2494. 2008.00456.x. |
[6] | Tobin DJ, Paus R. Graying: gerontobiology of the hair follicle pigmentary unit[J]. Exp Gerontol, 2001,36(1):29⁃54. doi: 10. 1016/s0531⁃5565(00)00210⁃2. |
[7] | Brandy DA. A technique for hair⁃grafting in between existing follicles in patients with early pattern baldness[J]. Dermatol Surg, 2000,26(8):801⁃805. doi: 10.1046/j.1524⁃4725.2000.00 011.x. |
[8] | Falabella R. What′s new in the treatment of vitiligo[J]. J Eur Acad Dermatol Venereol, 2001,15(4):287⁃289. |
[9] | 戴叶芹, 许爱娥. 单株毛囊移植治疗毛发部位白癜风的临床疗效[J]. 中华皮肤科杂志, 2010,43(12):880⁃881. |
[10] | Mokhtar M, El⁃Ashmawy AA, Mostafa WA, et al. Clinical and dermoscopic evaluation of follicular unit transplantation vs. Mini⁃Punch grafting in the repigmentation of resistant and stable vitiligo: a comparative study[J]. J Cosmet Dermatol, 2022,21(11):5837⁃5851. doi: 10.1111/jocd.15127. |
[11] | 中国中西医结合学会皮肤性病专业委员会皮肤外科学组. 白癜风外科治疗共识(2012)[J]. 中华皮肤科杂志, 2012,45(10):691⁃692. doi: 10.3760/cma.j.issn.0412⁃4030.2012.10.001. |
[12] | Menon SM, Sharma YK, Bansal P, et al. Restoration of pigmentation by follicular unit extraction transplant in three cases of focal vitiligo recalcitrant to therapy including with previous nonculture melanocyte⁃keratinocyte transplant[J]. Int J Trichology, 2016,8(2):87⁃88. doi: 10.4103/0974⁃7753.188041. |
[13] | Kumar A, Mohanty S, Sahni K, et al. Extracted hair follicle outer root sheath cell suspension for pigment cell restoration in vitiligo[J]. J Cutan Aesthet Surg, 2013,6(2):121⁃125. doi: 10.4103/0974⁃2077.112679. |
[14] | Ezz⁃Eldawla R, Abu El⁃Hamd M, Saied SM, et al. A comparative study between suction blistering graft, mini punch graft, and hair follicle transplant in treatment of patients with stable vitiligo[J]. J Dermatolog Treat, 2019,30(5):492⁃497. doi: 10.1080/09546 634.2018.1528329. |
[15] | Kim JC, Choi YC. Regrowth of grafted human scalp hair after removal of the bulb[J]. Dermatol Surg, 1995,21(4):312⁃313. doi: 10.1111/j.1524⁃4725.1995.tb00179.x. |
[16] | Arrunátegui A, Arroyo C, Garcia L, et al. Melanocyte reservoir in vitiligo[J]. Int J Dermatol, 1994,33(7):484⁃487. doi: 10.1111/j.1365⁃4362.1994.tb02860.x. |
[17] | 戴叶芹, 许爱娥, 彭建中. 分段毛囊移植治疗毛发部位白癜风[J]. 中华皮肤科杂志, 2020,53(6):462⁃464. doi: 10.35541/cjd. 20190685. |
[18] | Chen Y, Yan J, Chen X, et al. Comparative study between follicular unit transplantation with intact and non⁃intact hair bulb in treatment for stable vitiligo[J]. J Dermatolog Treat, 2022,33(2):818⁃821. doi: 10.1080/09546634.2020.1782320. |
[19] | Goldstein NB, Koster MI, Hoaglin LG, et al. Narrow band ultraviolet B treatment for human vitiligo is associated with proliferation, migration, and differentiation of melanocyte precursors[J]. J Invest Dermatol, 2015,135(8):2068⁃2076. doi: 10.1038/jid.2015.126. |
[20] | Goldstein NB, Steel A, Barbulescu CC, et al. Melanocyte precursors in the hair follicle bulge of repigmented vitiligo skin are controlled by RHO⁃GTPase, KCTD10, and CTNNB1 Signaling[J]. J Invest Dermatol, 2021,141(3):638⁃647.e13. doi: 10.1016/j.jid.2020.07.016. |
[21] | Baweja S, Chand S. A prospective observational comparative study of novel autologous negative pressure epidermal harvesting system (ANPEHS or EHS) and suction blister grafting (SBG) in treatment of stable vitiligo[J]. J Cutan Aesthet Surg, 2020,13(4):283⁃291. doi: 10.4103/JCAS.JCAS_18_20. |
[22] | Pangti R, Challa A, Chauhan S, et al. Comparison of cell suspension transplantation prepared from plucked hair shafts, excised hair follicles, and epidermal shave biopsies in vitiligo patients: a randomized study[J]. Dermatol Surg, 2021,47(5):735⁃738. doi: 10.1097/DSS.0000000000002337. |
[23] | Challa A, Chauhan S, Pangti R, et al. Evaluation of clinical efficacy and laboratory indicators of non⁃cultured epidermal cell suspension and hair follicle cell suspension in surgical management of stable vitiligo: a randomized comparative trial[J]. J Cosmet Dermatol, 2022,21(12):6958⁃6964. doi: 10.1111/jocd.15407. |
[24] | Lamoria A, Agrawal A, Rao P, et al. A comparative study between follicular unit transplantation and autologous non⁃cultured non⁃trypsinized epidermal cells grafting (Jodhpur Technique) in stable vitiligo[J]. J Cutan Aesthet Surg, 2020,13(3):204⁃209. doi: 10.4103/JCAS.JCAS_189_19. |
[25] | Gunaabalaji DR, Pangti R, Challa A, et al. Comparison of efficacy of noncultured hair follicle cell suspension and noncultured epidermal cell suspension in repigmentation of leukotrichia and skin patch in vitiligo: a randomized trial[J]. Int J Dermatol, 2020,59(11):1393⁃1400. doi: 10.1111/ijd.15188. |
[26] | Nilforoushzadeh MA, Nouri M, Alavi S, et al. Combination of epidermal keratinocyte⁃melanocyte cells suspension and microneedling: safe surgical approach in vitiligo[J]. J Cosmet Dermatol, 2022,21(10):4669⁃4676. doi: 10.1111/jocd.14987. |
[27] | Nilforoushzadeh MA, Farshi S, Nouri M, et al. Transplantation of autologous epidermal melanocyte⁃keratinocyte cells suspension for cell therapy of vitiligo: a clinical evaluation and biometric assessment[J]. J Cosmet Dermatol, 2022,21(12):7147⁃7152. doi: 10.1111/jocd.15423. |
[28] | Kawakami T. Surgical procedures and innovative approaches for vitiligo regenerative treatment and melanocytorrhagy[J]. J Dermatol, 2022,49(4):391⁃401. doi: 10.1111/1346⁃8138.16316. |
[29] | Bian Y, Yu H, Jin M, et al. Repigmentation by combined narrow⁃band ultraviolet B/adipose⁃derived stem cell transplantation in the mouse model: role of Nrf2/HO⁃1⁃mediated Ca2+ homeostasis[J]. Mol Med Rep, 2022,25(1):6[pii]. doi: 10.3892/ mmr.2021. 12522. |
[30] | Albalat W, Elsayed M, Salem A, et al. Microneedling and 5⁃flurouracil can enhance the efficacy of non⁃cultured epidermal cell suspension transplantation for resistant acral vitiligo[J]. Dermatol Ther, 2022,35(10):e15768. doi: 10.1111/dth.15768. |
[31] | El⁃Zawahry BM, Elmasry MF, Ragab A. The role of long⁃wavelength ultraviolet A1 (UVA1) in acral vitiligo[J]. J Cosmet Dermatol, 2019,18(4):1155⁃1160. doi: 10.1111/jocd.12808. |
[32] | Dalla A, Parsad D, Vinay K, et al. A prospective study to assess the efficacy of various surgical modalities in treatment of stable vitiligo patches over resistant sites[J]. Int J Dermatol, 2020,59(7):837⁃842. doi: 10.1111/ijd.14924. |
[33] | Rachmin I, Lee JH, Zhang B, et al. Stress⁃associated ectopic differentiation of melanocyte stem cells and ORS amelanotic melanocytes in an ex vivo human hair follicle model[J]. Exp Dermatol, 2021,30(4):578⁃587. doi: 10.1111/exd.14309. |
[34] | Razmi T M, Kumar R, Rani S, et al. Combination of follicular and epidermal cell suspension as a novel surgical approach in difficult⁃to⁃treat vitiligo: a randomized clinical trial[J]. JAMA Dermatol, 2018,154(3):301⁃308. doi: 10.1001/jamadermatol.2017. 5795. |
[35] | Arck PC, Overall R, Spatz K, et al. Towards a "free radical theory of graying": melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage[J]. FASEB J, 2006,20(9):1567⁃1569. doi: 10.1096/fj.05⁃4039 fje. |
[36] | Clark SA, Deppmann CD. How the stress of fight or flight turns hair white[J]. Nature, 2020,577(7792):623⁃624. doi: 10.1038/d41586⁃019⁃03949⁃8. |
[37] | Wu Y, Dai Y, Peng J, et al. Increased expression of β2⁃adrenoceptors is involved in vitiligo⁃associated grey hair[J]. J Eur Acad Dermatol Venereol, 2022,36(11):e949⁃e951. doi: 10. 1111/jdv.18380. |
[38] | Klingbeil KD, Fertig R. Eyebrow and eyelash hair transplantation: a systematic review[J]. J Clin Aesthet Dermatol, 2018,11(6):21⁃30. |
[39] | Wu Y, Dai Y, Wang T, et al. The application of electrolysis of depigmented hair using a trichiasis electrolyzer combined with single hair follicle transplantation for the treatment of vitiligo⁃associated leukotrichia[J]. Dermatol Ther, 2022,35(5):e15400. doi: 10.1111/dth.15400. |
[40] | Paus R, Cotsarelis G. The biology of hair follicles[J]. N Engl J Med, 1999,341(7):491⁃497. doi: 10.1056/NEJM19990812341 0706. |
[41] | Oh JW, Kloepper J, Langan EA, et al. A guide to studying human hair follicle cycling in vivo[J]. J Invest Dermatol, 2016,136(1):34⁃44. doi: 10.1038/JID.2015.354. |
[1] | Bai Lu, Chu Yan, Liu Yuanyuan, Zhu Caiyong. Treatment of chronic hand eczema [J]. Chinese Journal of Dermatology, 2025, 58(5): 477-480. |
[2] | Ding Yuxin, Miao Yujie, Mao Meiqi, Chen Jinyang, Lin Zhiwei, Lyu Zhongfa. Role of umbilical cord mesenchymal stem cell-derived nanovesicles in inducing hair regeneration [J]. Chinese Journal of Dermatology, 2025, 58(5): 431-439. |
[3] | The Consensus Development Expert Group on Diagnosis and Treatment of Port-wine Stain in Chinese Children, Pediatric Dermatologist Committee, China Dermatologist Association. Expert consensus on diagnosis and treatment of port-wine stain in children (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(5): 396-404. |
[4] | Skin Cancer Research Group, Committee on Dermatology, Chinese Association of Integrative Medicine, Melanoma Society of China Anti-Cancer Association, Society of Integrated Rehabilitation of Skin Tumors, China Anti-Cancer Association. Expert consensus on diagnosis and treatment of pigmented nevi (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(5): 387-395. |
[5] | Li Ziyu, Lu Yan. Paying attention to severe skin diseases after COVID-19 [J]. Chinese Journal of Dermatology, 2025, 58(4): 378-383. |
[6] | Xu Qiuyun, Ji Chao. Pyoderma gangrenosum-related systemic complications [J]. Chinese Journal of Dermatology, 2025, 58(4): 369-373. |
[7] | Lyu Mingyue, Man Xiaoyong. Application of cell therapy in systemic lupus erythematosus [J]. Chinese Journal of Dermatology, 2025, 58(4): 374-377. |
[8] | Wan Yongjun, Yang Haijing, Yan Qiao, Chen Mei, Wang Fengyuan, Su Qianya, Dong Zhengbang, Wang Fei. Clinical and prognostic analysis of nine cases of immune checkpoint inhibitor-related Stevens-Johnson syndrome/toxic epidermal necrolysis [J]. Chinese Journal of Dermatology, 2025, 58(4): 347-351. |
[9] | Group on Pediatric Dermatology, China Dermatologist Association, Committee on Psoriasis, Chinese Society of Dermatology. Expert consensus on the diagnosis and treatment of pediatric pustular psoriasis in China (2025 version) [J]. Chinese Journal of Dermatology, 2025, 58(4): 297-306. |
[10] | Chen Qitao, Li Yuqian, Shao Guanghui, Zhu Jing, Zhu Qilin, Li Zhongming, Du Xufeng, Fan Weixin. Erosive pustular dermatosis of the scalp [J]. Chinese Journal of Dermatology, 2025, 58(3): 272-275. |
[11] | Chinese Association of Rehabilitation Dermatology, Chinese Society of Dermatology, Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment. Clinical application of red, blue, and yellow light therapy in dermatology: an expert consensus statement (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(3): 209-215. |
[12] | Dermatology Professional Committee of Chinese Research Hospital Society, China Dermatologist Association. Guideline on phototherapy for vitiligo (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(3): 197-208. |
[13] | Luo Shuaihantian, Long Hai, Lu Qianjin. Research advances in systemic lupus erythematosus in 2024 [J]. Chinese Journal of Dermatology, 2025, 0(3): 20240689-e20240689. |
[14] | Xu Zhuohong, Hu Yu, Gu Heng. Role of mesenchymal stem cell-derived exosomes in skin diseases [J]. Chinese Journal of Dermatology, 2025, 0(3): 20220881-e20220881. |
[15] | Ye Hui, Deng Shilin, Liang Jingyao, Zhang Xibao. Correlations between the control of atopic dermatitis recurrence and tissue-resident memory T cells [J]. Chinese Journal of Dermatology, 2025, 0(3): 20240192-e20240192. |
|