Chinese Journal of Dermatology ›› 2024, Vol. 57 ›› Issue (8): 743-746.doi: 10.35541/cjd.20220278

• Dermatologic Surgery • Previous Articles     Next Articles

Dermabrasion for the treatment of familial benign chronic pemphigus: a clinical observation of 6 cases

Song Yuqing1, Yang Nan2, Liu Linlin1, Feng Ziyi1, Han Shixin1, Zhou Meijuan1   

  1. 1Department of Dermatology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning, China; 2Department of Plastic and Cosmetic Surgery, Army Medical Center, Chongqing 400042, China
    Song Yuqing and Yan Nan contributed equally to this article
  • Received:2022-04-22 Revised:2023-07-25 Online:2024-08-15 Published:2024-08-02
  • Contact: Zhou Meijuan E-mail:15541192290@163.com

Abstract: 【Abstract】 Objective To analyze clinical efficacy and safety of dermabrasion for the treatment of familial benign chronic pemphigus. Methods Clinical data were retrospectively collected from 6 patients with familial benign chronic pemphigus, who underwent dermabrasion in the Department of Dermatology, the First Affiliated Hospital of Dalian Medical University from February 2019 to July 2020. There were 3 males and 3 females, they were aged from 39 to 65 years, and their disease duration ranged from 10 to 40 years. All the patients were postoperatively followed up for 14 - 34 months. Response rates were calculated, and adverse reactions and recurrence were observed. Results Dermabrasion was performed on the 6 patients in 55 body areas. After operation, complete recovery was observed in 36 areas (65.5%), marked improvement was noted in 13 areas (23.6%), and moderate improvement was observed in 6 areas (10.9%); there were no areas with no response, resulting in an overall response rate of 89.1%. Postoperatively, the patients experienced no obvious discomfort, and only slight hypopigmentation and mild scars remained. During the follow-up of 14 to 34 months, no recurrence was observed in the treated areas. Conclusion Dermabrasion was safe and effective for the treatment of familial benign chronic pemphigus.

Key words: Pemphigus, benign familial, Dermabrasion, Surgical procedures, operative, Pathologic processes, Recurrence, Treatment outcome