中华皮肤科杂志 ›› 2026, Vol. 59 ›› Issue (11): 1036-1050.doi: 10.35541/cjd.20250333
中国医师协会皮肤科医师分会痤疮学组 中国中西医结合学会皮肤性病专业委员会痤疮学组 中华医学会皮肤性病学分会痤疮协作组 中国非公立医疗机构协会皮肤科分会
收稿日期:2025-06-16
修回日期:2026-06-03
发布日期:2026-11-03
通讯作者:
鞠强;项蕾红;何黎;郑志忠
E-mail:qiangju@aliyun.com; flora_xiang@vip.163.com; drheli2662@126.com; 5560732@qq.com
基金资助:Acne Study Group, China Dermatologist Association; Acne Study Group, Chinese Dermatovenerology Society of Integrative Medicine; Acne Group, Chinese Society of Dermatology; Dermatology Committee, Chinese Non-government Medical Institutions Association
Received:2025-06-16
Revised:2026-06-03
Published:2026-11-03
Contact:
Ju Qiang; Xiang Leihong; He Li; Zheng Zhizhong
E-mail:qiangju@aliyun.com; flora_xiang@vip.163.com; drheli2662@126.com; 5560732@qq.com
Supported by:摘要: 【摘要】 痤疮后遗症包括痤疮后遗红斑、色素沉着和瘢痕等,是炎症反应或处理不当等因素导致部分痤疮患者在痤疮皮疹消退后遗留下的皮损,临床上发病率高,疾病负担较重,给患者身心健康带来较大影响。目前治疗痤疮后遗症的方法众多,且新方法和新技术不断涌现,但存在疗效不一、治疗选择差异大等问题。为了使痤疮后遗症的诊断、预防和治疗进一步规范化,中国医师协会皮肤科医师分会痤疮学组、中国中西医结合学会皮肤性病专业委员会痤疮学组、中华医学会皮肤性病学分会痤疮协作组、中国非公立医疗机构协会皮肤科分会组织相关专家,通过检索国内外新近发表的文献资料并结合国内现状制订本共识,以期为临床评估和痤疮后遗症防治提供临床参考。
中国医师协会皮肤科医师分会痤疮学组 中国中西医结合学会皮肤性病专业委员会痤疮学组 中华医学会皮肤性病学分会痤疮协作组 中国非公立医疗机构协会皮肤科分会. 痤疮后遗症临床诊疗中国专家共识(2026版)[J]. 中华皮肤科杂志, 2026,59(11):1036-1050. doi:10.35541/cjd.20250333
Acne Study Group, China Dermatologist Association, Acne Study Group, Chinese Dermatovenerology Society of Integrative Medicine, Acne Group, Chinese Society of Dermatology, Dermatology Committee, Chinese Non-government Medical Institutions Association. Chinese expert consensus on clinical diagnosis and treatment of acne sequelae (2026)[J]. Chinese Journal of Dermatology, 2026, 59(11): 1036-1050.doi:10.35541/cjd.20250333
| [1] | Layton A, Alexis A, Baldwin H, et al. Identifying gaps and providing recommendations to address shortcomings in the investigation of acne sequelae by the Personalising Acne: Consensus of Experts panel[J]. JAAD Int, 2021,5:41⁃48. DOI: 10.1016/j.jdin.2021.06.006. |
| [2] | 中国痤疮治疗指南专家组. 中国痤疮治疗指南(2019修订版)[J]. 临床皮肤科杂志, 2019,48(9):583⁃588. DOI: 10. 16761/j.cnki.1000⁃4963.2019.09.020. |
| [3] | Abad⁃Casintahan F, Chow SK, Goh CL, et al. Frequency and characteristics of acne⁃related post⁃inflammatory hyperpigmentation[J]. J Dermatol, 2016,43(7):826⁃828. DOI: 10.1111/1346⁃8138.13263. |
| [4] | Taylor S, Elbuluk N, Grimes P, et al. Treatment recommendations for acne⁃associated hyperpigmentation: results of the Delphi consensus process and a literature review[J]. J Am Acad Dermatol, 2023,89(2):316⁃323. DOI: 10.1016/j.jaad.2023.02.053. |
| [5] | Kalantari Y, Dadkhahfar S, Etesami I. Post⁃acne erythema treatment: a systematic review of the literature[J]. J Cosmet Dermatol, 2022,21(4):1379⁃1392. DOI: 10.1111/jocd.14804. |
| [6] | Jennings T, Duffy R, McLarney M, et al. Acne scarring⁃pathophysiology, diagnosis, prevention and education: PartⅠ[J]. J Am Acad Dermatol, 2024,90(6):1123⁃1134. DOI: 10. 1016/j.jaad.2022.04.021. |
| [7] | 中华医学会医学美学与美容学分会激光美容学组, 中华医学会皮肤性病学分会美容激光学组, 中国医师协会美容与整形医师分会激光学组. 中国痤疮瘢痕治疗专家共识(2021)[J]. 中华皮肤科杂志, 2021,54(9):747⁃756. DOI: 10.35541/cjd. 20210182. |
| [8] | Howick J, Chalmers I, Glasziou P, et al. The 2011 Oxford CEBM levels of evidence (introductory document)[EB/OL]. [2026⁃06⁃17]. https://www.cebm.ox.ac.uk/resources/levels⁃of⁃evidence/ocebm⁃levels⁃of⁃evidence. |
| [9] | Bae⁃Harboe YS, Graber EM. Easy as PIE (postinflammatory erythema)[J]. J Clin Aesthet Dermatol, 2013,6(9):46⁃47. |
| [10] | Maghfour J, Olayinka J, Hamzavi IH, et al. A focused review on the pathophysiology of post⁃inflammatory hyperpigmentation[J]. Pigment Cell Melanoma Res, 2022,35(3):320⁃327. DOI: 10. 1111/pcmr.13038. |
| [11] | Panchaprateep R, Munavalli G. Low⁃fluence 585 nm Q⁃switched Nd:YAG laser: a novel laser treatment for post⁃acne erythema[J]. Lasers Surg Med, 2015,47(2):148⁃155. DOI: 10.1002/lsm. 22321. |
| [12] | Al⁃Quran L, Li G, Liu Z, et al. Comparative efficacy between intense pulsed light narrow spectrum and broad spectrum in the treatment of post⁃acne erythema (PAE)[J]. Clin Cosmet Investig Dermatol, 2023,16:1983⁃1996. DOI: 10.2147/CCID.S419743. |
| [13] | Ohanenye C, Taliaferro S, Callender VD. Diagnosing disorders of facial erythema[J]. Dermatol Clin, 2023,41(3):377⁃392. DOI: 10.1016/j.det.2023.02.004. |
| [14] | Goh CL, Abad⁃Casintahan F, Chow SK, et al. Evaluating acne⁃related post⁃inflammatory hyperpigmentation is a challenge even amongst experts[J]. J Dermatol, 2014,41(12):1106⁃1108. DOI: 10.1111/1346⁃8138.12667. |
| [15] | Elbuluk N, Grimes P, Chien A, et al. The Pathogenesis and management of acne⁃induced post⁃inflammatory hyperpigmentation[J]. Am J Clin Dermatol, 2021,22(6):829⁃836. DOI: 10.1007/s40257⁃021⁃00633⁃4. |
| [16] | Abanmi A, Al⁃Enezi M, Al Hammadi A, et al. Survey of acne⁃related post⁃inflammatory hyperpigmentation in the Middle East[J]. J Dermatolog Treat, 2019,30(6):578⁃581. DOI: 10.1080/09546634.2018.1542807. |
| [17] | Bhargava S, Cunha PR, Lee J, et al. Acne scarring management: systematic review and evaluation of the evidence[J]. Am J Clin Dermatol, 2018,19(4):459⁃477. DOI: 10.1007/s40257⁃018⁃0358⁃5. |
| [18] | Tan J, Kang S, Leyden J. Prevalence and risk factors of acne scarring among patients consulting dermatologists in the USA[J]. J Drugs Dermatol, 2017,16(2):97⁃102. |
| [19] | Liu L, Xue Y, Chen Y, et al. Prevalence and risk factors of acne scars in patients with acne vulgaris[J]. Skin Res Technol, 2023,29(6):e13386. DOI: 10.1111/srt.13386. |
| [20] | Asilian A, Faghihi G, Asemi Esfahani A, et al. Comparison of two methods of subcision Nokor and blunt blade in acne scars treatment[J]. J Cosmet Dermatol, 2019,18(6):1788⁃1793. DOI: 10.1111/jocd.12981. |
| [21] | Rocha M, Barnes F, Calderón J, et al. Acne treatment challenges ⁃ recommendations of Latin American expert consensus[J]. An Bras Dermatol, 2024,99(3):414⁃424. DOI: 10.1016/j.abd.2023. 09.001. |
| [22] | Davis EC, Callender VD. A review of acne in ethnic skin: pathogenesis, clinical manifestations, and management strategies[J]. J Clin Aesthet Dermatol, 2010,3(4):24⁃38. |
| [23] | Amiri R, Khalili M, Mohammadi S, et al. Treatment protocols and efficacy of light and laser treatments in post⁃acne erythema[J]. J Cosmet Dermatol, 2022,21(2):648⁃656. DOI: 10.1111/jocd.14729. |
| [24] | Agamia N, El⁃Nagdy S, El⁃Ariny A. A split face comparative study using a novel triple combination therapy for the treatment of persistent post acne erythema[J]. Dermatol Ther, 2022,35(4):e15327. DOI: 10.1111/dth.15327. |
| [25] | Al⁃Qarqaz F, Bodoor K, Baba A, et al. Post⁃acne hyperpigmentation: evaluation of risk factors and the use of artificial neural network as a predictive classifier[J]. Dermatol Reports, 2021,13(3):8223. DOI: 10.4081/dr.2021.8223. |
| [26] | Say YH, Heng A, Reginald K, et al. Modifiable and non⁃modifiable epidemiological risk factors for acne, acne severity and acne scarring among Malaysian Chinese: a cross⁃sectional study[J]. BMC Public Health, 2021,21(1):601. DOI: 10.1186/s12889⁃021⁃10681⁃4. |
| [27] | National Guideline Alliance (UK). Evidence review for risk factors for scarring due to acne vulgaris: acne vulgaris: management[M/OL]. London:National Institute for Health and Care Excellence (NICE),2021. https://www.ncbi.nlm.nih.gov/books/NBK573051/. |
| [28] | Heng A, Say YH, Sio YY, et al. Epidemiological risk factors associated with acne vulgaris presentation, severity, and scarring in a Singapore Chinese Population: a cross⁃sectional study[J]. Dermatology, 2022,238(2):226⁃235. DOI: 10.1159/000516232. |
| [29] | Moon J, Yoon JY, Yang JH, et al. Atrophic acne scar: a process from altered metabolism of elastic fibres and collagen fibres based on transforming growth factor⁃β1 signalling[J]. Br J Dermatol, 2019,181(6):1226⁃1237. DOI: 10.1111/bjd.17851. |
| [30] | Carlavan I, Bertino B, Rivier M, et al. Atrophic scar formation in patients with acne involves long⁃acting immune responses with plasma cells and alteration of sebaceous glands[J]. Br J Dermatol, 2018,179(4):906⁃917. DOI: 10.1111/bjd.16680. |
| [31] | Berman B, Maderal A, Raphael B. Keloids and hypertrophic scars: pathophysiology, classification, and treatment[J]. Dermatol Surg, 2017,43 Suppl 1:S3⁃S18. DOI: 10.1097/DSS.000000000 0000819. |
| [32] | Fearmonti R, Bond J, Erdmann D, et al. A review of scar scales and scar measuring devices[J]. Eplasty, 2010,10:e43. |
| [33] | Abdlaty R, Hayward J, Farrell T, et al. Skin erythema and pigmentation: a review of optical assessment techniques[J]. Photodiagnosis Photodyn Ther, 2021,33:102127. DOI: 10.1016/j.pdpdt.2020.102127. |
| [34] | Lekwuttikarn R, Tempark T, Chatproedprai S, et al. Randomized, controlled trial split⁃faced study of 595⁃nm pulsed dye laser in the treatment of acne vulgaris and acne erythema in adolescents and early adulthood[J]. Int J Dermatol, 2017,56(8):884⁃888. DOI: 10.1111/ijd.13631. |
| [35] | 王向熙, 李臻臻, 赖彦云, 等. 585 nm Q开关激光治疗痤疮炎症性皮损和炎症后红斑的疗效[J]. 北京大学学报(医学版), 2022,54(2):283⁃288. DOI: 10.19723/j.issn.1671⁃167X.2022.02.014. |
| [36] | Yoon HJ, Lee DH, Kim SO, et al. Acne erythema improvement by long⁃pulsed 595⁃nm pulsed⁃dye laser treatment: a pilot study[J]. J Dermatolog Treat, 2008,19(1):38⁃44. DOI: 10.1080/09546630701646164. |
| [37] | Jia X, Zheng L, Fang L, et al. Evaluation of the safety and efficacy of a fractional picosecond 1064 nm laser for post⁃acne erythema in adult Chinese patients[J]. Skin Res Technol, 2023,29(1):e13274. DOI: 10.1111/srt.13274. |
| [38] | Agamia N, Essawy M, Kassem A. Successful treatment of the face post acne erythema using a topically applied selective alpha 1⁃adrenergic receptor agonist, oxymetazoline 1.5%, a controlled left to right face comparative trial[J]. J Dermatolog Treat, 2022,33(2):904⁃909. DOI: 10.1080/09546634.2020.1789045. |
| [39] | Tan J, Liu H, Leyden JJ, et al. Reliability of clinician erythema assessment grading scale[J]. J Am Acad Dermatol, 2014,71(4):760⁃763. DOI: 10.1016/j.jaad.2014.05.044. |
| [40] | Taylor SC, Arsonnaud S, Czernielewski J, et al. The Taylor Hyperpigmentation Scale: a new visual assessment tool for the evaluation of skin color and pigmentation[J]. Cutis, 2005,76(4):270⁃274. |
| [41] | Savory SA, Agim NG, Mao R, et al. Reliability assessment and validation of the postacne hyperpigmentation index (PAHPI), a new instrument to measure postinflammatory hyperpigmentation from acne vulgaris[J]. J Am Acad Dermatol, 2014,70(1):108⁃114. DOI: 10.1016/j.jaad.2013.09.017. |
| [42] | Khelife A, Diouf A, Diop A, et al. Reliability assessment and validation of the post⁃acne hyperpigmentation index (PAHPI) in a population from Sub⁃Saharan Africa in Senegal[J]. Ann Dermatol Venereol, 2023,150(1):24⁃27. DOI: 10.1016/j.annder. 2022.05.005. |
| [43] | 李贞, 施银银, 侯将莹, 等. 黄金微针结合氨甲环酸透皮给药治疗痤疮炎症后色素沉着的效果[J]. 中华医学美学美容杂志, 2024,30(1):19⁃23. DOI: 10.3760/cma.j.issn.1671⁃0290. 2024.01.004. |
| [44] | Tawfic SO, Abdel Hay R, Salim H, et al. Tranexamic acid versus fractional carbon dioxide laser in post⁃acne hyperpigmentation[J]. Dermatol Ther, 2021,34(6):e15103. DOI: 10.1111/dth. 15103. |
| [45] | Sobhan M, Talebi⁃Ghane E, Poostiyan E. A comparative study of 20% azelaic acid cream versus 5% tranexamic acid solution for the treatment of postinflammatory hyperpigmentation in patients with acne vulgaris: a single⁃blinded randomized clinical trial[J]. J Res Med Sci, 2023,28:18. DOI: 10.4103/jrms.jrms_443_22. |
| [46] | Silpa⁃Archa N, Kohli I, Chaowattanapanit S, et al. Postinflammatory hyperpigmentation: a comprehensive overview: epidemiology, pathogenesis, clinical presentation, and noninvasive assessment technique[J]. J Am Acad Dermatol, 2017,77(4):591⁃605. DOI: 10.1016/j.jaad.2017.01.035. |
| [47] | 中国临床瘢痕防治专家共识制定小组. 中国临床瘢痕防治专家共识[J]. 中华损伤与修复杂志(电子版), 2017,12(6):401⁃408. DOI: 10.3877/cma.j.issn.1673⁃9450.2017.06.001. |
| [48] | Goodman GJ, Baron JA. Postacne scarring: a qualitative global scarring grading system[J]. Dermatol Surg, 2006,32(12):1458⁃1466. DOI: 10.1111/j.1524⁃4725.2006.32354.x. |
| [49] | Goodman GJ, Baron JA. Postacne scarring⁃⁃a quantitative global scarring grading system[J]. J Cosmet Dermatol, 2006,5(1):48⁃52. DOI: 10.1111/j.1473⁃2165.2006.00222.x. |
| [50] | Dreno B, Khammari A, Orain N, et al. ECCA grading scale: an original validated acne scar grading scale for clinical practice in dermatology[J]. Dermatology, 2007,214(1):46⁃51. DOI: 10. 1159/000096912. |
| [51] | Baryza MJ, Baryza GA. The Vancouver Scar Scale: an administration tool and its interrater reliability[J]. J Burn Care Rehabil, 1995,16(5):535⁃538. DOI: 10.1097/00004630⁃19950 9000⁃00013. |
| [52] | Draaijers LJ, Tempelman FR, Botman YA, et al. The patient and observer scar assessment scale: a reliable and feasible tool for scar evaluation[J]. Plast Reconstr Surg, 2004,113(7):1960⁃1965; discussion 1966⁃1967. DOI: 10.1097/01.prs.0000122207. 28773.56. |
| [53] | Choo A, Ong YS, Issa F. Scar assessment tools: how do they compare?[J]. Front Surg, 2021,8:643098. DOI: 10.3389/fsurg. 2021.643098. |
| [54] | Jaspers MEH, Moortgat P. Objective assessment tools: physical parameters in scar assessment[M/OL]//Téot L, Mustoe TA, Middelkoop E, et al. Textbook on scar management: state of the art management and emerging technologies. Cham (CH): Springer, 2020:149⁃158.https://www.ncbi.nlm.nih.gov/books/NBK586073. |
| [55] | Kurokawa I, Watanabe M, Hayashibe K. Effect of a cosmetic use with 2% isostearyl⁃l⁃ascorbic acid gel for postinflammatory hyperpigmentation and postinflammatory erythema in acne vulgaris[J]. J Cosmet Dermatol Sci Appl, 2020,10(1):28⁃32. DOI: 10.4236/jcdsa.2020.101004. |
| [56] | Kurokawa I, Yoshioka M, Ito S. Split⁃face comparative clinical trial using glyceryl⁃octyl⁃ascorbic acid/ascorbyl 2⁃phosphate 6⁃palmitate/DL⁃α⁃tocopherol phosphate complex treatment for postinflammatory hyperpigmentation, postinflammatory erythema and atrophic scar in acne vulgaris[J]. J Dermatol, 2019,46(10):e347⁃e348. DOI: 10.1111/1346⁃8138.14930. |
| [57] | Chalermsuwiwattanakan N, Rojhirunsakool S, Kamanamool N, et al. The comparative study of efficacy between 1064⁃nm long⁃pulsed Nd:YAG laser and 595⁃nm pulsed dye laser for the treatment of acne vulgaris[J]. J Cosmet Dermatol, 2021,20(7):2108⁃2115. DOI: 10.1111/jocd.13832. |
| [58] | Kim JH, Choe SJ, Kim TG. Post⁃acne erythema successfully treated with 595⁃nm picosecond⁃domain neodymium:yttrium⁃aluminum⁃garnet laser[J]. Medical Lasers, 2020, 9(1): 84⁃87. DOI: 10.25289/ML.2020.9.1.84. |
| [59] | Mathew ML, Karthik R, Mallikarjun M, et al. Intense pulsed light therapy for acne⁃induced post⁃inflammatory erythema[J]. Indian Dermatol Online J, 2018,9(3):159⁃164. DOI: 10.4103/idoj.IDOJ_306_17. |
| [60] | 苏虹, 杨智, 谭雅心, 等. 强脉冲光及595nm染料激光治疗面部痤疮后红斑自身对比研究[J]. 中华皮肤科杂志, 2017,50(3):177⁃181. DOI: 10.3760/cma.j.issn.0412⁃4030.2017.03.006. |
| [61] | Wu X, Wang X, Wu X, et al. Intense pulsed light therapy improves acne⁃induced post⁃inflammatory erythema and hyperpigmentation: a retrospective study in Chinese patients[J]. Dermatol Ther (Heidelb), 2022,12(5):1147⁃1156. DOI: 10. 1007/s13555⁃022⁃00719⁃9. |
| [62] | Liang Y, Li L. The combination of red and blue light, radiofrequency and intense pulsed light for the treatment of facial postacne erythema[J]. Clin Cosmet Investig Dermatol, 2022,15:2383⁃2389. DOI: 10.2147/CCID.S389705. |
| [63] | Park KY, Ko EJ, Seo SJ, et al. Comparison of fractional, nonablative, 1550⁃nm laser and 595⁃nm pulsed dye laser for the treatment of facial erythema resulting from acne: a split⁃face, evaluator⁃blinded, randomized pilot study[J]. J Cosmet Laser Ther, 2014,16(3):120⁃123. DOI: 10.3109/14764172.2013.854626. |
| [64] | Wanitphakdeedecha R, Cembrano K, Ungaksornpairote C, et al. The efficacy and safety of a 577⁃nm high⁃power optically pumped semiconductor laser in the treatment of postacne erythema[J]. J Cosmet Dermatol, 2020,19(7):1642⁃1647. DOI: 10.1111/jocd.13474. |
| [65] | Wen X, Li Y, Hamblin MR, et al. A randomized split⁃face, investigator⁃blinded study of a picosecond alexandrite laser for post⁃inflammatory erythema and acne scars[J]. Dermatol Ther, 2020,33(6):e13941. DOI: 10.1111/dth.13941. |
| [66] | Min S, Park SY, Yoon JY, et al. Fractional microneedling radiofrequency treatment for acne⁃related post⁃inflammatory erythema[J]. Acta Derm Venereol, 2016,96(1):87⁃91. DOI: 10.2340/00015555⁃2164. |
| [67] | Dan Y, Chen L, Jin S, et al. The Therapeutic and preventive effects of light⁃emitting diode (LED) for post⁃inflammatory erythema and hyperpigmentation: a pilot study[J]. Photodermatol Photoimmunol Photomed, 2025,41(2):e70003. DOI: 10.1111/phpp.70003. |
| [68] | Genedy R M. Topical brimonidine tartrate as a novel treatment for facial erythema of rosacea and acne erythema[J]. J Egypt Women Dermatol Soc, 2016,13(2):55⁃64. DOI: 10.1097/01.Ewx.0000483162.96767.73. |
| [69] | Jakhar D, Kaur I. Topical 5% tranexamic acid for acne⁃related postinflammatory erythema[J]. J Am Acad Dermatol, 2020,82(6):e187⁃e188. DOI: 10.1016/j.jaad.2019.09.074. |
| [70] | Liu X, Qi X, He Y, et al. Effect of intense pulsed light combined with 3% tranexamic acid for facial erythema associated with acne vulgaris and rosacea[J]. Lasers Surg Med, 2025,57(6):490⁃495. DOI: 10.1002/lsm.70029. |
| [71] | Mhatre M, Sharma A, Agrawal S. Topical tacrolimus for acne⁃related macular erythema to prevent atrophic scarring[J]. J Am Acad Dermatol, 2022,86(6):e253⁃e254. DOI: 10.1016/j.jaad. 2020.06.077. |
| [72] | Afra TP, Razmi T M, De D. Topical timolol for postacne erythema[J]. J Am Acad Dermatol, 2021,84(6):e255⁃e256. DOI: 10. 1016/j.jaad.2020.04.144. |
| [73] | Keyhanianr S, Warnke K, Buerger A, et al. Efficacy of a cosmetic formulation containing licochalcone a, salicylic acid, decanediol and sebum⁃regulating technology with l⁃carnitine in subjects with acne lesions[EB/OL].[2026⁃10⁃22]. https://www.wcd2019milan⁃ dl.org/abstract⁃book/documents/abstracts/01⁃acne⁃rosacea⁃related⁃disorders/efficacy⁃of⁃a⁃cosmetic⁃formulation⁃2286.pdf. |
| [74] | Shucheng H, Zhou X, Du D, et al. Effects of 15% azelaic acid gel in the management of post⁃inflammatory erythema and post⁃inflammatory hyperpigmentation in acne vulgaris[J]. Dermatol Ther (Heidelb), 2024,14(5):1293⁃1314. DOI: 10.1007/s13555⁃024⁃01176⁃2. |
| [75] | 李平平, 梁伟, 张真, 等. 长脉宽1064 nm Nd:YAG 激光治疗中重度痤疮伴痤疮后红斑的疗效[J]. 山东大学学报(医学版), 2015,53(11):85⁃88. DOI: 10.6040/j.issn.1671⁃7554.0. 2015.507. |
| [76] | Faghihi G, Isfahani AK, Hosseini SM, et al. Efficacy of intense pulsed light combined with topical erythromycin solution 2% versus topical erythromycin solution 2% alone in the treatment of persistent facial erythematous acne macules[J]. Adv Biomed Res, 2012,1:70. DOI: 10.4103/2277⁃9175.102974. |
| [77] | Sarac G, Kapicioglu Y, Cenk H. An evaluation of the efficacy of a single⁃session 577 nm pro⁃yellow laser treatment in patients with postacne erythema and scarring[J]. Dermatol Ther, 2021,34(1):e14611. DOI: 10.1111/dth.14611. |
| [78] | Washrawirul C, Puaratana⁃Arunkon T, Chongpison Y, et al. The role of the topical nasal decongestant oxymetazoline as a novel therapeutic option for post⁃acne erythema: a split⁃face, double⁃blind, randomized, placebo⁃controlled trial[J]. J Dermatol, 2023,50(6):739⁃745. DOI: 10.1111/1346⁃8138.16749. |
| [79] | Leyden J, Stein⁃Gold L, Weiss J. Why topical retinoids are mainstay of therapy for acne[J]. Dermatol Ther (Heidelb), 2017,7(3):293⁃304. DOI: 10.1007/s13555⁃017⁃0185⁃2. |
| [80] | Callender VD, Baldwin H, Cook⁃Bolden FE, et al. Effects of topical retinoids on acne and post⁃inflammatory hyperpigmentation in patients with skin of color: a clinical review and implications for practice[J]. Am J Clin Dermatol, 2022,23(1):69⁃81. DOI: 10.1007/s40257⁃021⁃00643⁃2. |
| [81] | Davis EC, Callender VD. Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color[J]. J Clin Aesthet Dermatol, 2010,3(7):20⁃31. |
| [82] | Park S, Huang L, Ao X, et al. Micronized acellular dermal matrix combined with platelet rich plasma in the treatment of atrophic acne scars: a self⁃controlled split face study[J]. J Cosmet Dermatol, 2024,23(7):2386⁃2391. DOI: 10.1111/jocd.16293. |
| [83] | Taylor S, Grimes P, Lim J, et al. Postinflammatory hyperpigmentation[J]. J Cutan Med Surg, 2009,13(4):183⁃191. DOI: 10.2310/7750.2009.08077. |
| [84] | Bhardwaj V, Sharma K, Maksimovic S, et al. Professional⁃grade TCA⁃lactic acid chemical peel: elucidating mode of action to treat photoaging and hyperpigmentation[J]. Front Med (Lausanne), 2021,8:617068. DOI: 10.3389/fmed.2021.617068. |
| [85] | 中华医学会皮肤性病学分会, 中国医师协会皮肤科医师分会, 中国中西医结合学会皮肤性病专业委员会. 中国化学剥脱术临床应用专家共识(2022)[J]. 中华皮肤科杂志, 2022,55(11):949⁃955. DOI: 10.35541/cjd.20220309. |
| [86] | How KN, Lim PY, Wan Ahmad Kammal W, et al. Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double⁃blinded, split⁃face, controlled trial[J]. Int J Dermatol, 2020,59(7):804⁃812. DOI: 10.1111/ijd.14948. |
| [87] | Roggenkamp D, Dlova N, Mann T, et al. Effective reduction of post⁃inflammatory hyperpigmentation with the tyrosinase inhibitor isobutylamido⁃thiazolyl⁃resorcinol (Thiamidol)[J]. Int J Cosmet Sci, 2021,43(3):292⁃301. DOI: 10.1111/ics.12694. |
| [88] | Kolbe L, Immeyer J, Batzer J, et al. Anti⁃inflammatory efficacy of licochalcone A: correlation of clinical potency and in vitro effects[J]. Arch Dermatol Res, 2006,298(1):23⁃30. DOI: 10. 1007/s00403⁃006⁃0654⁃4. |
| [89] | Wanitphakdeedecha R, Tavechodperathum N, Tantrapornpong P, et al. Acne treatment efficacy of intense pulsed light photodynamic therapy with topical licochalcone A, l⁃carnitine, and decanediol: a spilt⁃face, double⁃blind, randomized controlled trial[J]. J Cosmet Dermatol, 2020,19(1):78⁃87. DOI: 10.1111/jocd.13178. |
| [90] | Kircik LH. Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post⁃inflammatory hyperpigmentation and acne: a 16⁃week, baseline⁃controlled study[J]. J Drugs Dermatol, 2011,10(6):586⁃590. |
| [91] | Brito S, Baek JM, Cha B, et al. Nicotinamide mononucleotide reduces melanin production in aged melanocytes by inhibiting cAMP/Wnt signaling[J]. J Dermatol Sci, 2022,106(3):159⁃169. DOI: 10.1016/j.jdermsci.2022.05.002. |
| [92] | Madaan P, Sikka P, Malik DS. Cosmeceutical aptitudes of niacinamide: a review[J]. Recent Adv Antiinfect Drug Discov, 2021,16(3):196⁃208. DOI: 10.2174/277243441666621112910 5629. |
| [93] | 龙淼, 任宏珊, 张世园. 果酸换肤联合强脉冲光对痤疮后色素沉着改善的疗效观察[J]. 中国美容医学, 2023,32(8):81⁃84. |
| [94] | 韩朋, 张洁, 王艳玲, 等. 光子嫩肤联合调Q激光治疗痤疮后色素沉着效果观察[J]. 中国美容整形外科杂志, 2023,34(6):321⁃324,369. DOI: 10.3969/j.issn.1673⁃7040.2023.06.001. |
| [95] | 宋婷, 刘艳, 杨枫, 等. 低能量调Q激光与氨甲环酸注射治疗痤疮后色素沉着的临床疗效[J]. 中国激光医学杂志, 2023,32(2):81⁃86. DOI: 10.13480/j.issn1003⁃9430.2023.0081. |
| [96] | Callender VD, Young CM, Kindred C, et al. Efficacy and safety of clindamycin phosphate 1.2% and tretinoin 0.025% gel for the treatment of acne and acne⁃induced post⁃inflammatory hyperpigmentation in patients with skin of color[J]. J Clin Aesthet Dermatol, 2012,5(7):25⁃32. |
| [97] | Grimes P, Callender V. Tazarotene cream for postinflammatory hyperpigmentation and acne vulgaris in darker skin: a double⁃blind, randomized, vehicle⁃controlled study[J]. Cutis, 2006,77(1):45⁃50. |
| [98] | Bulengo⁃Ransby SM, Griffiths CE, Kimbrough⁃Green CK, et al. Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patients[J]. N Engl J Med, 1993,328(20):1438⁃1443. DOI: 10.1056/NEJM 199305203282002. |
| [99] | Sarkar R, Ghunawat S, Garg VK. Comparative study of 35% glycolic acid, 20% salicylic⁃10% mandelic acid, and phytic acid combination peels in the treatment of active acne and postacne pigmentation[J]. J Cutan Aesthet Surg, 2019,12(3):158⁃163. DOI: 10.4103/JCAS.JCAS_135_18. |
| [100] | O'Brien L, Jones DJ. Silicone gel sheeting for preventing and treating hypertrophic and keloid scars[J]. Cochrane Database Syst Rev, 2013,(9):CD003826. DOI: 10.1002/14651858.CD003826.pub3. |
| [101] | Lin J, Wang X. Effects of botulinum toxin type A in the prevention and treatment of facial hypertrophic scars: a meta⁃analysis[J]. Int Wound J, 2024,21(3):e14796. DOI: 10.1111/iwj.14796. |
| [102] | Kim WI, Kim S, Cho SW, et al. The efficacy of bleomycin for treating keloid and hypertrophic scar: a systematic review and meta⁃analysis[J]. J Cosmet Dermatol, 2020,19(12):3357⁃3366. DOI: 10.1111/jocd.13390. |
| [103] | Mavilakandy AK, Vayalapra S, Minty I, et al. Comparing combination triamcinolone acetonide and 5⁃fluorouracil with monotherapy triamcinolone acetonide or 5⁃fluorouracil in the treatment of hypertrophic scars: a systematic review and meta⁃analysis[J]. Plast Reconstr Surg, 2024,153(6):1318⁃1330. DOI: 10.1097/PRS.0000000000010867. |
| [104] | 洪素庄, 张婧婧, 洪帆. A型肉毒毒素治疗痤疮性瘢痕的远期随访观察[J]. 中华整形外科杂志, 2016,32(6):432⁃437. DOI: 10.3760/cma.j.issn.1009⁃4598.2016.06.009. |
| [105] | Callaghan DJ. Review on the treatment of scars[J]. Plast Aesthet Res, 2020, 7:66. DOI: 10.20517/2347⁃9264.2020.166. |
| [106] | Jfri A, Alajmi A, Alazemi M, et al. Acne scars: an update on management[J]. Skin Therapy Lett, 2022,27(6):6⁃9. |
| [107] | Salameh F, Shumaker PR, Goodman GJ, et al. Energy⁃based devices for the treatment of acne scars: 2022 International consensus recommendations[J]. Lasers Surg Med, 2022,54(1):10⁃26. DOI: 10.1002/lsm.23484. |
| [108] | Mu YZ, Jiang L, Yang H. The efficacy of fractional ablative carbon dioxide laser combined with other therapies in acne scars[J]. Dermatol Ther, 2019,32(6):e13084. DOI: 10.1111/dth. 13084. |
| [109] | Manuskiatti W, Iamphonrat T, Wanitphakdeedecha R, et al. Comparison of fractional erbium⁃doped yttrium aluminum garnet and carbon dioxide lasers in resurfacing of atrophic acne scars in Asians[J]. Dermatol Surg, 2013,39(1 Pt 1):111⁃120. DOI: 10.1111/dsu.12030. |
| [110] | Kwon HH, Park HY, Choi SC, et al. Combined fractional treatment of acne scars involving non⁃ablative 1,550⁃nm erbium⁃glass laser and micro⁃needling radiofrequency: a 16⁃week prospective, randomized split⁃face study[J]. Acta Derm Venereol, 2017,97(8):947⁃951. DOI: 10.2340/00015555⁃2701. |
| [111] | Arsiwala NZ, Inamadar AC, Adya KA. A comparative study to assess the efficacy of fractional carbon dioxide laser and combination of fractional carbon dioxide laser with topical autologous platelet⁃rich plasma in post⁃acne atrophic scars[J]. J Cutan Aesthet Surg, 2020,13(1):11⁃17. DOI: 10.4103/JCAS.JCAS_142_19. |
| [112] | Kim J, Lee SG, Choi S, et al. Combination of fractional microneedling radiofrequency and ablative fractional laser versus ablative fractional laser alone for acne and acne scars[J]. Yonsei Med J, 2023,64(12):721⁃729. DOI: 10.3349/ymj. 2023.0234. |
| [113] | Faghihi G, Nouraei S, Asilian A, et al. Efficacy of punch elevation combined with fractional carbon dioxide laser resurfacing in facial atrophic acne scarring: a randomized split⁃face clinical study[J]. Indian J Dermatol, 2015,60(5):473⁃478. DOI: 10.4103/0019⁃5154.159616. |
| [114] | El⁃Taieb MA, Ibrahim HM, Hegazy EM, et al. Fractional Erbium⁃YAG laser and platelet⁃rich plasma as single or combined treatment for atrophic acne scars: a randomized clinical trial[J]. Dermatol Ther (Heidelb), 2019,9(4):707⁃717. DOI: 10.1007/s13555⁃019⁃00318⁃1. |
| [115] | Liu X, Zou T, Cao Y, et al. Comparison of multiple 1565 nm fractional Er: glass laser and single fractional CO2 laser in the treatment of atrophic acne scars: a prospective, randomized split⁃face study[J]. J Cosmet Laser Ther, 2025,27(1⁃2):17⁃23. DOI: 10.1080/14764172.2025.2459629. |
| [116] | Li MY, Huang YL, Chen JH, et al. Effectiveness and safety of energy⁃based devices for acne scars: a network meta⁃analysis of randomized controlled trials[J]. Facial Plast Surg Aesthet Med, 2023,25(6):521⁃527. DOI: 10.1089/fpsam.2022.0383. |
| [117] | Zhao Z, Wang T, Li W, et al. To evaluate the efficacy and safety of laser interventions for facial acne scars: a systematic review and Bayesian network meta⁃analysis[J]. Ann Transl Med, 2022,10(24):1396. DOI: 10.21037/atm⁃22⁃5997. |
| [118] | Sadick NS, Cardona A. Laser treatment for facial acne scars: a review[J]. J Cosmet Laser Ther, 2018,20(7⁃8):424⁃435. DOI: 10.1080/14764172.2018.1461230. |
| [119] | Lee DH, Choi YS, Min SU, et al. Comparison of a 585⁃nm pulsed dye laser and a 1064⁃nm Nd:YAG laser for the treatment of acne scars: a randomized split⁃face clinical study[J]. J Am Acad Dermatol, 2009,60(5):801⁃807. DOI: 10.1016/j.jaad. 2008.11.883. |
| [120] | Ael⁃S A, Ibrahim SM, Muhammad MM. Pulsed dye laser versus long⁃pulsed Nd:YAG laser in the treatment of hypertrophic scars and keloid: a comparative randomized split⁃scar trial[J]. J Cosmet Laser Ther, 2016,18(4):208⁃212. DOI: 10.3109/14764172.2015.1114648. |
| [121] | Feng H, Wu Y, Jiang M, et al. The efficacy and safety of fractional 1064 nm Nd:YAG picosecond laser combined with intense pulsed light in the treatment of atrophic acne scar: a split⁃face study[J]. Lasers Surg Med, 2021,53(10):1356⁃1363. DOI: 10.1002/lsm.23428. |
| [122] | Li J, Duan F, Kuang J. Meta⁃analysis of fractional radiofrequency treatment for acne and/or acne scars[J]. J Cosmet Dermatol, 2022,21(12):6754⁃6766. DOI: 10.1111/jocd.15348. |
| [123] | Dai R, Xie H, Hua W, et al. The efficacy and safety of the fractional radiofrequency technique for the treatment of atrophic acne scar in Asians: a meta⁃analysis[J]. J Cosmet Laser Ther, 2017,19(6):337⁃344. DOI: 10.1080/14764172.2017.1314507. |
| [124] | Min S, Park SY, Yoon JY, et al. Comparison of fractional microneedling radiofrequency and bipolar radiofrequency on acne and acne scar and investigation of mechanism: comparative randomized controlled clinical trial[J]. Arch Dermatol Res, 2015,307(10):897⁃904. DOI: 10.1007/s00403⁃015⁃1601⁃z. |
| [125] | Tam C, Khong J, Tam K, et al. A comprehensive review of non⁃energy⁃based treatments for atrophic acne scarring[J]. Clin Cosmet Investig Dermatol, 2022,15:455⁃469. DOI: 10.2147/CCID.S350040. |
| [126] | 曾昂, 刘志飞, 朱琳, 等. 机械磨削结合皮肤活性细胞移植技术治疗面部痤疮后瘢痕[J]. 中华整形外科杂志, 2014,(6):417⁃420. DOI: 10.3760/cma.j.issn.1009⁃4598.2014.06.005. |
| [127] | Gupta A, Kaur M, Patra S, et al. Evidence⁃based surgical management of post⁃acne scarring in skin of color[J]. J Cutan Aesthet Surg, 2020,13(2):124⁃141. DOI: 10.4103/JCAS.JCAS_154_19. |
| [128] | Barikbin B, Akbari Z, Yousefi M, et al. Blunt blade subcision: an evolution in the treatment of atrophic acne scars[J]. Dermatol Surg, 2017,43 Suppl 1:S57⁃S63. DOI: 10.1097/DSS.0000000000000650. |
| [129] | Zhu J, Zhang Y, Wang W, et al. Treatment of acne scars using subcision combined with concentrated growth factors versus subcision monotherapy: a retrospective cohort study[J]. Arch Dermatol Res, 2025,317(1):481. DOI: 10.1007/s00403⁃025⁃04027⁃y. |
| [130] | Al⁃Dhalimi MA, Arnoos AA. Subcision for treatment of rolling acne scars in Iraqi patients: a clinical study[J]. J Cosmet Dermatol, 2012,11(2):144⁃150. DOI: 10.1111/j.1473⁃2165. 2012.00616.x. |
| [131] | Ramadan SA, El⁃Komy MH, Bassiouny DA, et al. Subcision versus 100% trichloroacetic acid in the treatment of rolling acne scars[J]. Dermatol Surg, 2011,37(5):626⁃633. DOI: 10.1111/j.1524⁃4725.2011.01954.x. |
| [132] | Gheisari M, Iranmanesh B, Saghi B. Blunt cannula subcision is more effective than Nokor needle subcision for acne scars treatment[J]. J Cosmet Dermatol, 2019,18(1):192⁃196. DOI: 10.1111/jocd.12523. |
| [133] | Boen M, Jacob C. A review and update of treatment options using the acne scar classification system[J]. Dermatol Surg, 2019,45(3):411⁃422. DOI: 10.1097/DSS.0000000000001765. |
| [134] | Grevelink JM, White VR. Concurrent use of laser skin resurfacing and punch excision in the treatment of facial acne scarring[J]. Dermatol Surg, 1998,24(5):527⁃530. DOI: 10. 1111/j.1524⁃4725.1998.tb04201.x. |
| [135] | Zhao T, Li M, Wang J, et al. Comparison of the effects of adipose extracellular matrix/stromal vascular fraction gel injection and CO2 fractional laser on atrophic acne scar in asians through a 24⁃week prospective, randomized, split⁃face study[J]. J Cosmet Dermatol, 2025,24(3):e70131. DOI: 10.1111/jocd.70131. |
| [136] | Munavalli GS, Smith S, Maslowski JM, et al. Successful treatment of depressed, distensible acne scars using autologous fibroblasts: a multi⁃site, prospective, double blind, placebo⁃controlled clinical trial[J]. Dermatol Surg, 2013,39(8):1226⁃1236. DOI: 10.1111/dsu.12204. |
| [137] | Almukhadeb E, Binkhonain F, Alkahtani A, et al. Dermal fillers in the treatment of acne scars: a review[J]. Ann Dermatol, 2023,35(6):400⁃407. DOI: 10.5021/ad.22.230. |
| [138] | Karnik J, Baumann L, Bruce S, et al. A double⁃blind, randomized, multicenter, controlled trial of suspended polymethylmethacrylate microspheres for the correction of atrophic facial acne scars[J]. J Am Acad Dermatol, 2014,71(1):77⁃83. DOI: 10.1016/j.jaad.2014.02.034. |
| [139] | Goldberg DJ, Amin S, Hussain M. Acne scar correction using calcium hydroxylapatite in a carrier⁃based gel[J]. J Cosmet Laser Ther, 2006,8(3):134⁃136. DOI: 10.1080/147641706008 91632. |
| [140] | Sapra S, Stewart JA, Mraud K, et al. A Canadian study of the use of poly⁃L⁃lactic acid dermal implant for the treatment of hill and valley acne scarring[J]. Dermatol Surg, 2015,41(5):587⁃594. DOI: 10.1097/DSS.0000000000000366. |
| [141] | Sun C, Lim D. Chemical peels for atrophic acne scarring: evolution of peel types and methods[J]. Australas J Dermatol, 2023,64(1):18⁃27. DOI: 10.1111/ajd.13959. |
| [142] | Kontochristopoulos G, Platsidaki E. Chemical peels in active acne and acne scars[J]. Clin Dermatol, 2017,35(2):179⁃182. DOI: 10.1016/j.clindermatol.2016.10.011. |
| [143] | Kurokawa I, Oiso N, Kawada A. Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non⁃inflamed atrophic scars in acne vulgaris[J]. J Dermatol, 2017,44(4):401⁃405. DOI: 10.1111/1346⁃8138.13634. |
| [144] | Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylic⁃mandelic acid peels in active acne vulgaris and post⁃acne scarring and hyperpigmentation: a comparative study[J]. Dermatol Surg, 2009,35(1):59⁃65. DOI: 10.1111/j.1524⁃4725.2008.34383.x. |
| [145] | Ali B, ElMahdy N, Elfar NN. Microneedling (Dermapen) and Jessner's solution peeling in treatment of atrophic acne scars: a comparative randomized clinical study[J]. J Cosmet Laser Ther, 2019,21(6):357⁃363. DOI: 10.1080/14764172.2019.166 1490. |
| [146] | Khunger N, Bhardwaj D, Khunger M. Evaluation of CROSS technique with 100% TCA in the management of ice pick acne scars in darker skin types[J]. J Cosmet Dermatol, 2011,10(1):51⁃57. DOI: 10.1111/j.1473⁃2165.2010.00526.x. |
| [147] | Agarwal N, Gupta LK, Khare AK, et al. Therapeutic response of 70% trichloroacetic acid CROSS in atrophic acne scars[J]. Dermatol Surg, 2015,41(5):597⁃604. DOI: 10.1097/DSS.000 0000000000355. |
| [148] | Ebrahimi Z, Alimohamadi Y, Janani M, et al. Platelet⁃rich plasma in the treatment of scars, to suggest or not to suggest? A systematic review and meta⁃analysis[J]. J Tissue Eng Regen Med, 2022,16(10):875⁃899. DOI: 10.1002/term.3338. |
| [149] | Chen J, Wan Y, Lin Y, et al. Fractional carbon dioxide laser or Erbium:yttrium⁃aluminum⁃garnet laser assisted by topical application/intradermal injection of platelet⁃rich plasma for postacne scars[J]. Plast Reconstr Surg, 2021,148(6):915e⁃927e. DOI: 10.1097/PRS.0000000000008513. |
| [150] | Chen Q, Yu N, Liu Z, et al. The clinical efficacy of ReCell® autologous cell regeneration techniques combined with dermabrasion treatment in acne scars[J]. Aesthetic Plast Surg, 2020,44(2):535⁃542. DOI: 10.1007/s00266⁃019⁃01481⁃8. |
| [151] | Ibrahim ZA, Eltatawy RA, Ghaly NR, et al. Autologus bone marrow stem cells in atrophic acne scars: a pilot study[J]. J Dermatolog Treat, 2015,26(3):260⁃265. DOI: 10.3109/09546 634.2014.946379. |
| [152] | Villani A, Carmela Annunziata M, Antonietta Luciano M, et al. Skin needling for the treatment of acne scarring: a comprehensive review[J]. J Cosmet Dermatol, 2020,19(9):2174⁃2181. DOI: 10.1111/jocd.13577. |
| [153] | Mujahid N, Shareef F, Maymone M, et al. Microneedling as a treatment for acne scarring: a systematic review[J]. Dermatol Surg, 2020,46(1):86⁃92. DOI: 10.1097/DSS.000000000000 2020. |
| [154] | Sitohang I, Sirait S, Suryanegara J. Microneedling in the treatment of atrophic scars: a systematic review of randomised controlled trials[J]. Int Wound J, 2021,18(5):577⁃585. DOI: 10.1111/iwj.13559. |
| [155] | Shen YC, Chiu WK, Kang YN, et al. Microneedling monotherapy for acne scar: systematic review and meta⁃analysis of randomized controlled trials[J]. Aesthetic Plast Surg, 2022,46(4):1913⁃1922. DOI: 10.1007/s00266⁃022⁃02845⁃3. |
| [156] | Kim HJ, Kim TG, Kwon YS, et al. Comparison of a 1,550 nm Erbium: glass fractional laser and a chemical reconstruction of skin scars (CROSS) method in the treatment of acne scars: a simultaneous split⁃face trial[J]. Lasers Surg Med, 2009,41(8):545⁃549. DOI: 10.1002/lsm.20796. |
| [157] | Lan T, Tang L, Xia A, et al. Comparison of fractional micro⁃plasma radiofrequency and fractional microneedle radiofrequency for the treatment of atrophic acne scars: a pilot randomized split⁃face clinical study in China[J]. Lasers Surg Med, 2021,53(7):906⁃913. DOI: 10.1002/lsm.23369. |
| [158] | Leheta T, El Tawdy A, Abdel Hay R, et al. Percutaneous collagen induction versus full⁃concentration trichloroacetic acid in the treatment of atrophic acne scars[J]. Dermatol Surg, 2011,37(2):207⁃216. DOI: 10.1111/j.1524⁃4725.2010.01854.x. |
| [159] | Alam M, Han S, Pongprutthipan M, et al. Efficacy of a needling device for the treatment of acne scars: a randomized clinical trial[J]. JAMA Dermatol, 2014,150(8):844⁃849. DOI: 10.1001/jamadermatol.2013.8687. |
| [160] | El⁃Domyati M, Abdel⁃Wahab H, Hossam A. Microneedling combined with platelet⁃rich plasma or trichloroacetic acid peeling for management of acne scarring: a split⁃face clinical and histologic comparison[J]. J Cosmet Dermatol, 2018,17(1):73⁃83. DOI: 10.1111/jocd.12459. |
| [161] | Al⁃Dhalimi MA, Dahham Z. Split⁃face clinical comparative study of fractional Er:YAG (2940nm) laser versus long pulsed Nd:YAG (1064nm) laser in treatment of atrophic acne scar[J]. J Cosmet Laser Ther, 2021,23(1⁃2):35⁃40. DOI: 10.1080/14764172.2021.1967996. |
| [162] | Lu K, Cai S. Efficacy and safety comparison between 1927 nm thulium laser and 2940 nm Er:YAG laser in the treatment of facial atrophic acne scarring: a prospective, simultaneous spilt⁃face clinical trial[J]. Lasers Med Sci, 2022,37(3):2025⁃2031. DOI: 10.1007/s10103⁃021⁃03465⁃0. |
| [163] | Sirithanabadeekul P, Tantrapornpong P, Rattakul B, et al. Comparison of fractional picosecond 1064⁃nm laser and fractional carbon dioxide laser for treating atrophic acne scars: a randomized split⁃face trial[J]. Dermatol Surg, 2021,47(2):e58⁃e65. DOI: 10.1097/DSS.0000000000002572. |
| [1] | 中国医师协会皮肤科医师分会 中华医学会皮肤性病学分会 中国医疗保健国际交流促进会皮肤医学分会 中国罕见病联盟皮肤病学分会 . [开放获取] 斑块状银屑病生物制剂长程治疗管理专家共识(2026版)[J]. 中华皮肤科杂志, 2026, 59(9): 827-843. |
| [2] | 唐祯 刘宇航 杨凌 胡凌雪 贺治杰 曹凯 丁澍. 反射式共聚焦显微镜在皮肤型红斑狼疮诊断与鉴别诊断中的价值及特征分析[J]. 中华皮肤科杂志, 2026, 59(9): 873-880. |
| [3] | 陈星宇 姚煦. 中性粒细胞在炎症性皮肤病中的研究进展[J]. 中华皮肤科杂志, 2026, 59(9): 905-910. |
| [4] | 李燕红 姜琨 吴卓璇 章建兰 方美珍 刘姝婷 王琳琳 胡磊 周小勇 陈柳青 陈金波. 程序性死亡受体1抑制剂相关皮肤不良反应18例临床资料分析[J]. 中华皮肤科杂志, 2026, 59(8): 783-787. |
| [5] | 《西罗莫司治疗卡波西样血管内皮瘤中国专家共识(版)》制订专家组. 西罗莫司治疗卡波西样血管内皮瘤中国专家共识(2026版)[J]. 中华皮肤科杂志, 2026, 59(8): 728-737. |
| [6] | 中华医学会皮肤性病学分会 中国医师协会皮肤科医师分会. 中国皮肤鳞状细胞癌诊疗指南(2026版)[J]. 中华皮肤科杂志, 2026, 59(8): 703-716. |
| [7] | 《脓疱型银屑病诊疗中国专家共识(版)》编写委员会专家组. [开放获取] 脓疱型银屑病诊疗中国专家共识(2026版)[J]. 中华皮肤科杂志, 2026, 59(8): 717-727. |
| [8] | 魏瑾 闫会文 张建中 伦文辉. 司库奇尤单抗治疗合并人类免疫缺陷病毒感染的中重度斑块状银屑病10例临床疗效观察[J]. 中华皮肤科杂志, 2026, 59(7): 671-674. |
| [9] | 王琳琳 曹立娟 陈柳青 李东升 胡燕燕. 海姆泊芬光动力疗法治疗四肢鲜红斑痣疗效观察及安全性回顾分析[J]. 中华皮肤科杂志, 2026, 59(7): 637-644. |
| [10] | 刘怿菲 金炫沃 刘鹏月 张希萌 吴严. 点阵CO2激光联合A型肉毒毒素外用治疗面部毛孔粗大的半脸自身对照临床试验[J]. 中华皮肤科杂志, 2026, 59(7): 645-653. |
| [11] | 张国龙 赵子君. 氨基酮戊酸光动力疗法治疗皮肤鳞状细胞癌的现状、挑战和思考[J]. 中华皮肤科杂志, 2026, 59(7): 626-631. |
| [12] | 中国研究型医院学会皮肤科学专业委员会 中国医师协会皮肤科医师分会. [开放获取] 窄谱中波紫外线光疗皮肤科临床应用指南(2026版)[J]. 中华皮肤科杂志, 2026, 59(7): 595-610. |
| [13] | 中华医学会皮肤性病学分会光动力治疗研究协作组 中国康复医学会皮肤病康复专业委员会及光动力治疗与康复专业委员会 中国医学装备协会皮肤病与皮肤美容分会光医学治疗装备学组. 氨基酮戊酸光动力疗法治疗尖锐湿疣的临床应用指南(2026版)[J]. 中华皮肤科杂志, 2026, 59(7): 611-618. |
| [14] | 李芳 林颖. 头颈部特应性皮炎的诊疗研究进展[J]. 中华皮肤科杂志, 2026, 59(6): 586-590. |
| [15] | 孙松朋 龙俊红 褚洪川 周阳洋 刘甲鑫 刘彦 霍兴霄 陈航 荆涛 高静 王艳逊 王锐 李振宇 张书信. 肤痔清软膏与曲安奈德益康唑乳膏治疗肛周慢性湿疹的临床疗效和安全性:一项多中心、随机、对照、双盲、等效性研究[J]. 中华皮肤科杂志, 2026, 59(6): 564-570. |
|