氨基酮戊酸光动力疗法治疗尖锐湿疣的临床应用指南（2026版）

doi:10.35541/cjd.20250702

中华皮肤科杂志 ›› 2026, Vol. 59 ›› Issue (7): 611-618.doi: 10.35541/cjd.20250702

• 指南与共识·光皮肤病学 • 上一篇下一篇

氨基酮戊酸光动力疗法治疗尖锐湿疣的临床应用指南（2026版）

中华医学会皮肤性病学分会光动力治疗研究协作组中国康复医学会皮肤病康复专业委员会及光动力治疗与康复专业委员会中国医学装备协会皮肤病与皮肤美容分会光医学治疗装备学组

中华医学会皮肤性病学分会光动力治疗研究协作组中国康复医学会皮肤病康复专业委员会及光动力治疗与康复专业委员会中国医学装备协会皮肤病与皮肤美容分会光医学治疗装备学组

收稿日期:2025-12-16 修回日期:2026-05-13 发布日期:2026-07-03
通讯作者: 王秀丽；高兴华；李玉叶 E-mail:wangxiuli_1400023@tongji.edu.cn;gaobarry@hotmail.com; yyeli2000@126.com

Guideline for the clinical application of aminolevulinic acid-based photodynamic therapy in the treatment of condyloma acuminatum （2026 edition）

Photodynamic Therapy Research Cooperative Group, Chinese Society of Dermatology; Chinese Association of Rehabilitation Dermatology & Photodynamic Therapy; Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment

Photodynamic Therapy Research Cooperative Group, Chinese Society of Dermatology; Chinese Association of Rehabilitation Dermatology & Photodynamic Therapy; Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment

Received:2025-12-16 Revised:2026-05-13 Published:2026-07-03
Contact: Wang Xiuli; Gao Xinghua; Li Yuye E-mail:wangxiuli_1400023@tongji.edu.cn;gaobarry@hotmail.com; yyeli2000@126.com

摘要/Abstract

摘要： 【摘要】氨基酮戊酸光动力疗法（ALA-PDT）治疗尖锐湿疣具有治愈率高、复发率低、不良反应少等优点，已成为尖锐湿疣的常规治疗方法。为进一步规范、指导和推动ALA-PDT在尖锐湿疣中的临床应用，本指南从ALA-PDT的作用机制、推荐治疗方案、治疗前后宣教、治疗疗程与随访、不良反应处理、与其他治疗方法的联合应用以及特殊人群的治疗等方面，提出ALA-PDT治疗尖锐湿疣的规范化诊疗建议，尤其纳入了改良无痛PDT方案，供我国皮肤科、妇科、泌尿科及肛肠科从事相关诊疗工作的医师、护士临床实践参考。

关键词: 尖锐湿疣, 治疗, 氨基酮戊酸光动力疗法, 指南, 临床应用

Abstract: 【Abstract】 Aminolevulinic acid-based photodynamic therapy （ALA-PDT） has become a conventional treatment for condyloma acuminatum owing to its high cure rate, low recurrence rate, and mild adverse reactions. To further standardize, guide, and promote the clinical application of ALA-PDT in the management of condyloma acuminatum, this guideline provides standardized diagnostic and therapeutic recommendations from multiple aspects, including the mechanisms of action, treatment protocols, patient education before and after treatment, treatment course and follow-up, management of adverse reactions, combination with other therapeutic modalities, and treatment in special populations. Notably, a modified painless PDT protocol has been incorporated. This guideline is intended to serve as a practical reference for dermatologists, gynecologists, urologists, and proctologists, as well as nurses engaged in related clinical practice in China.

Key words: Condylomata acuminata, Therapy, Aminolevulinic acid-based photodynamic therapy, Guideline, Clinical application

中华医学会皮肤性病学分会光动力治疗研究协作组中国康复医学会皮肤病康复专业委员会及光动力治疗与康复专业委员会中国医学装备协会皮肤病与皮肤美容分会光医学治疗装备学组. 氨基酮戊酸光动力疗法治疗尖锐湿疣的临床应用指南（2026版）[J]. 中华皮肤科杂志, 2026,59(7):611-618. doi:10.35541/cjd.20250702

Photodynamic Therapy Research Cooperative Group, Chinese Society of Dermatology, Chinese Association of Rehabilitation Dermatology & Photodynamic Therapy, Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment. Guideline for the clinical application of aminolevulinic acid-based photodynamic therapy in the treatment of condyloma acuminatum （2026 edition）[J]. Chinese Journal of Dermatology, 2026, 59(7): 611-618.doi:10.35541/cjd.20250702

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氨基酮戊酸光动力疗法治疗尖锐湿疣的临床应用指南（2026版）

Guideline for the clinical application of aminolevulinic acid-based photodynamic therapy in the treatment of condyloma acuminatum （2026 edition）

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