中华皮肤科杂志 ›› 2023, Vol. 56 ›› Issue (2): 177-180.doi: 10.35541/cjd.20200587

• 综述 • 上一篇    下一篇

肠道菌群与黑素瘤免疫检查点抑制剂治疗的研究进展

李婷婷    康晓静   

  1. 新疆维吾尔自治区人民医院皮肤性病科  新疆皮肤病研究重点实验室(XJYS1707),乌鲁木齐  830001
  • 收稿日期:2020-06-12 修回日期:2020-11-15 发布日期:2023-02-01
  • 通讯作者: 康晓静 E-mail:drkangxj666@163.com
  • 基金资助:
    新疆维吾尔自治区创新环境(人才、基地)建设专项“天山创新团队计划”项目(2020D14006)

Gut microbiota and immune checkpoint inhibitor treatment of melanoma

Li Tingting, Kang Xiaojing   

  1. Department of Dermatology, People′s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research(XJYS1707), Urumqi 830001, China
  • Received:2020-06-12 Revised:2020-11-15 Published:2023-02-01
  • Contact: Kang Xiaojing E-mail:drkangxj666@163.com
  • Supported by:
    Autonomous Region Innovation Environment (Talent, Base) Construction Project “Tianshan Innovation Team Plan”(2020D14006)

摘要: 【摘要】 越来越多的研究表明,肠道菌群通过多种机制影响黑素瘤的发展,且在黑素瘤治疗过程中扮演重要的角色。本文就肠道菌群与黑素瘤发展的关系,肠道菌群对黑素瘤免疫检查点抑制剂治疗及相关不良反应的影响作一综述。

关键词: 痣和黑素瘤, 宏基因组, 免疫治疗, 肠道菌群, 免疫检查点抑制剂

Abstract: 【Abstract】 A growing number of studies have shown that gut microbiota affects the development of melanoma through various mechanisms, and plays a vital role in the treatment of melanoma. This review summarizes the relationship between gut microbiota and the development of melanoma, the effect of gut microbiota on the checkpoint blockade immunotherapy of melanoma and related adverse effects.

Key words: Nevi and melanomas, Metagenome, Immunotherapy, Gut microbiota, Immune checkpoint inhibitors

引用本文

李婷婷 康晓静. 肠道菌群与黑素瘤免疫检查点抑制剂治疗的研究进展[J]. 中华皮肤科杂志, 2023,56(2):177-180. doi:10.35541/cjd.20200587

Li Tingting, Kang Xiaojing. Gut microbiota and immune checkpoint inhibitor treatment of melanoma[J]. Chinese Journal of Dermatology, 2023, 56(2): 177-180.doi:10.35541/cjd.20200587