中华皮肤科杂志 ›› 2024, Vol. 57 ›› Issue (7): 665-667.doi: 10.35541/cjd.20210536

• 综述 • 上一篇    下一篇

Merkel细胞癌治疗新进展

杨爱民1    成将伟2    黄嘉诚1    岑瑛3    陈俊杰3   

  1. 1四川大学华西临床医学院,成都  610044;2中国医科大学附属第一医院,沈阳  110001;3四川大学华西医院烧伤整形外科,成都  610044
  • 收稿日期:2021-07-23 修回日期:2022-04-29 发布日期:2024-07-02
  • 通讯作者: 岑瑛;陈俊杰 E-mail:cenyinghx@163.com; cjjemail@163.com
  • 基金资助:
    四川省科技计划重点研发项目(2020YFS0267)

Treatment of Merkel cell carcinoma

Yang Aimin1, Cheng Jiangwei2, Huang Jiacheng1, Cen Ying3, Chen Junjie3   

  1. 1West China School of Medicine, West China Hospital, Sichuan University, Chengdu 610044, China; 2The First Hospital of China Medical University, Shenyang 110001, China; 3Department of Burns and Plastic Surgery, West China Hospital, Sichuan University, Chengdu 610044, China
  • Received:2021-07-23 Revised:2022-04-29 Published:2024-07-02
  • Contact: Cen Ying; Chen Junjie E-mail:cenyinghx@163.com; cjjemail@163.com
  • Supported by:
    Key Research and Development Projects of Sichuan Science and Technology Department(2020YFS0267)

摘要: 【摘要】 手术切除和放疗常规用于早中期Merkel细胞癌的治疗。近年来,针对晚期Merkel细胞癌,基于其免疫原性特征的免疫治疗已被证明有效。本文主要综述Merkel细胞癌的治疗进展,为其合理诊治提供参考。

关键词: 癌, Merkel细胞, 神经内分泌瘤, 梅克尔细胞多瘤病毒, 免疫疗法, 免疫检查点抑制剂

Abstract: 【Abstract】 Surgical resection and radiotherapy have been frequently applied to the treatment of early- and intermediate-stage Merkel cell carcinoma. In recent years, immunotherapy based on immunogenic characteristics of Merkel cell carcinoma has been proved to be effective in the treatment of advanced Merkel cell carcinoma. This review focuses on advances in the treatment of Merkel cell carcinoma, and provides a reference for its clinical diagnosis and treatment.

Key words: Carcinoma, Merkel cell, Neuroendocrine tumor, Merkel cell polyomavirus, Immunotherapy, Immune checkpoint inhibitor

引用本文

杨爱民 成将伟 黄嘉诚 岑瑛 陈俊杰. Merkel细胞癌治疗新进展[J]. 中华皮肤科杂志, 2024,57(7):665-667. doi:10.35541/cjd.20210536

Yang Aimin, Cheng Jiangwei, Huang Jiacheng, Cen Ying, Chen Junjie. Treatment of Merkel cell carcinoma[J]. Chinese Journal of Dermatology, 2024, 57(7): 665-667.doi:10.35541/cjd.20210536