Chinese Journal of Dermatology ›› 2021, Vol. 54 ›› Issue (10): 910-914.doi: 10.35541/cjd.20191072

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Extracellular vesicles in dermatology: updates and prospects

Chen Wei1, Xie Heng2, Li Li3   

  1. 1Department of Medical Cosmetology, Chengdu Second People′s Hospital, Chengdu 610017, China; 2 Department of Medical Cosmetology, Guangdong Provincial Dermatology Hospital, Guangzhou 510095, China; 3Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China

  • Received:2019-11-10 Revised:2020-03-14 Online:2021-10-15 Published:2021-09-28
  • Contact: Li Li E-mail:hxskin2017@qq.com

Abstract: 【Abstract】 Extracellular vesicles are nanoscale vesicles secreted by cells, including exosomes and microvesicles. They can be ingested by recipient cells through a variety of mechanisms, transmitting intercellular information and regulating biological functions of recipient cells. Studies have found that extracellular vesicles are closely related to skin diseases, such as autoimmune diseases, pigmented diseases, tumors and wound healing, and play important biological roles in various physiological and pathological processes. This review summarizes updates on extracellular vesicles in dermatology.

Key words: Exosomes, Extracellular vesicles, Microvesicles, Skin diseases