Chinese Journal of Dermatology ›› 2023, Vol. 56 ›› Issue (6): 567-570.doi: 10.35541/cjd.20220918
• Reviews • Previous Articles
Zhang Liming, Xiao Ting
Received:2022-12-27
Revised:2023-03-23
Online:2023-06-15
Published:2023-06-05
Contact:
Xiao Ting
E-mail:cmuxt@126.com
Supported by:Zhang Liming, Xiao Ting. Update of the autoimmune pathogenesis of chronic spontaneous urticaria[J]. Chinese Journal of Dermatology, 2023, 56(6): 567-570.doi:10.35541/cjd.20220918
| ［1］ | Zuberbier T, Abdul Latiff AH, Abuzakouk M, et al. The international EAACI/GA2LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria［J］. Allergy, 2022,77（3）:734⁃766. doi: 10.1111/all. 15090. |
| ［2］ | Leznoff A, Josse RG, Denburg J, et al. Association of chronic urticaria and angioedema with thyroid autoimmunity［J］. Arch Dermatol, 1983,119（8）:636⁃640. doi: 10.1001/archderm.119. 8.636. |
| ［3］ | Grattan CE, Francis DM, Hide M, et al. Detection of circulating histamine releasing autoantibodies with functional properties of anti⁃IgE in chronic urticaria［J］. Clin Exp Allergy, 1991,21（6）:695⁃704. doi: 10.1111/j.1365⁃2222.1991.tb03198.x. |
| ［4］ | Hide M, Francis DM, Grattan CE, et al. Autoantibodies against the high⁃affinity IgE receptor as a cause of histamine release in chronic urticaria［J］. N Engl J Med, 1993,328（22）:1599⁃1604. doi: 10.1056/NEJM199306033282204. |
| ［5］ | Bar⁃Sela S, Reshef T, Mekori YA. IgE antithyroid microsomal antibodies in a patient with chronic urticaria［J］. J Allergy Clin Immunol, 1999,103（6）:1216⁃1217. doi: 10.1016/s0091⁃6749（99）70204⁃6. |
| ［6］ | Konstantinou GN, Asero R, Ferrer M, et al. EAACI taskforce position paper: evidence for autoimmune urticaria and proposal for defining diagnostic criteria［J］. Allergy, 2013,68（1）:27⁃36. doi: 10.1111/all.12056. |
| ［7］ | Schoepke N, Asero R, Ellrich A, et al. Biomarkers and clinical characteristics of autoimmune chronic spontaneous urticaria: Results of the PURIST Study［J］. Allergy, 2019,74（12）:2427⁃2436. doi: 10.1111/all.13949. |
| ［8］ | Kolkhir P, Altrichter S, Asero R, et al. Autoimmune diseases are linked to type IIb autoimmune chronic spontaneous urticaria［J］. Allergy Asthma Immunol Res, 2021,13（4）:545⁃559. doi: 10. 4168/aair.2021.13.4.545. |
| ［9］ | Maronese CA, Ferrucci SM, Moltrasio C, et al. IgG and IgE autoantibodies to IgE receptors in chronic spontaneous urticaria and their role in the response to mmalizumab［J］. J Clin Med, 2023,12（1）:378. doi: 10.3390/jcm12010378. |
| ［10］ | Panaszek B, Pawłowicz R, Grzegrzółka J, et al. Autoreactive IgE in chronic spontaneous/idiopathic urticaria and basophil/mastocyte priming phenomenon, as a feature of autoimmune nature of the syndrome［J］. Arch Immunol Ther Exp （Warsz）, 2017,65（2）:137⁃143. doi: 10.1007/s00005⁃016⁃0417⁃7. |
| ［11］ | de Montjoye L, Darrigade AS, Giménez⁃Arnau A, et al. Correlations between disease activity, autoimmunity and biological parameters in patients with chronic spontaneous urticaria［J］. Eur Ann Allergy Clin Immunol, 2021,53（2）:55⁃66. doi: 10.23822/EurAnnACI.1764⁃1489.132. |
| ［12］ | Oda Y, Fukunaga A, Washio K, et al. Improved FcεRI⁃mediated CD203c basophil responsiveness reflects rapid responses to omalizumab in chronic spontaneous urticaria［J］. J Allergy Clin Immunol Pract, 2021,9（3）:1166⁃1176.e8. doi: 10.1016/j.jaip. 2020.08.048. |
| ［13］ | Huang AH, Chichester KL, Saini SS. Association of basophil parameters with disease severity and duration in chronic spontaneous urticaria （CSU）［J］. J Allergy Clin Immunol Pract, 2020,8（2）:793⁃795.e6. doi: 10.1016/j.jaip.2019.08.004. |
| ［14］ | Oda Y, Fukunaga A, Washio K, et al. Low responsiveness of basophils via FcεRI reflects disease activity in chronic spontaneous urticaria［J］. J Allergy Clin Immunol Pract, 2019,7（8）:2835⁃2844.e7. doi: 10.1016/j.jaip.2019.05.020. |
| ［15］ | Hashimoto T, Yokozeki H, Karasuyama H, et al. IL⁃31⁃generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin［J］. J Allergy Clin Immunol, 2023,151（3）:737⁃746.e6. doi: 10.1016/j.jaci.2022.11.009. |
| ［16］ | Kaplan AP, Giménez⁃Arnau AM, Saini SS. Mechanisms of action that contribute to efficacy of omalizumab in chronic spontaneous urticaria［J］. Allergy, 2017,72（4）:519⁃533. doi: 10.1111/all. 13083. |
| ［17］ | Kay AB, Ying S, Ardelean E, et al. Calcitonin gene⁃related peptide and vascular endothelial growth factor are expressed in lesional but not uninvolved skin in chronic spontaneous urticaria［J］. Clin Exp Allergy, 2014,44（8）:1053⁃1060. doi: 10.1111/cea. 12348. |
| ［18］ | Yanase Y, Takahagi S, Hide M. Chronic spontaneous urticaria and the extrinsic coagulation system［J］. Allergol Int, 2018,67（2）:191⁃194. doi: 10.1016/j.alit.2017.09.003. |
| ［19］ | Rauber MM, Pickert J, Holiangu L, et al. Omalizumab response correlates with reduced IFN⁃γ⁃, IL⁃10⁃ and IL⁃31⁃secreting cells in chronic spontaneous urticaria［J］. J Eur Acad Dermatol Venereol, 2020,34（9）:2078⁃2085. doi: 10.1111/jdv.16216. |
| ［20］ | Grieco T, Porzia A, Paolino G, et al. IFN⁃γ/IL⁃6 and related cytokines in chronic spontaneous urticaria: evaluation of their pathogenetic role and changes during omalizumab therapy［J］. Int J Dermatol, 2020,59（5）:590⁃594. doi: 10.1111/ijd.14812. |
| ［21］ | de Montjoye L, Choteau M, Herman A, et al. IL⁃6 and IL⁃1β expression is increased in autologous serum skin test of patients with chronic spontaneous urticaria［J］. Allergy, 2019,74（12）:2522⁃2524. doi: 10.1111/all.13928. |
| ［22］ | Toubi E, Vadasz Z. The emerging role of IL⁃17 in the immune⁃pathogenesis of chronic spontaneous urticaria［J］. Immunotargets Ther, 2020,9:217⁃223. doi: 10.2147/ITT.S266410. |
| ［23］ | Sabag DA, Matanes L, Bejar J, et al. Interleukin⁃17 is a potential player and treatment target in severe chronic spontaneous urticaria［J］. Clin Exp Allergy, 2020,50（7）:799⁃804. doi: 10. 1111/cea.13616. |
| ［24］ | Auyeung P, Mittag D, Hodgkin PD, et al. Autoreactive T cells in chronic spontaneous urticaria target the IgE Fc receptor Iα subunit［J］. J Allergy Clin Immunol, 2016,138（3）:761⁃768.e4. doi: 10.1016/j.jaci.2016.04.036. |
| ［25］ | Bracken SJ, Abraham S, MacLeod AS. Autoimmune theories of chronic spontaneous urticaria［J］. Front Immunol, 2019,10:627. doi: 10.3389/fimmu.2019.00627. |
| ［26］ | Kolkhir P, Church MK, Weller K, et al. Autoimmune chronic spontaneous urticaria: what we know and what we do not know［J］. J Allergy Clin Immunol, 2017,139（6）:1772⁃1781.e1. doi: 10.1016/j.jaci.2016.08.050. |
| ［27］ | Altrichter S, Peter HJ, Pisarevskaja D, et al. IgE mediated autoallergy against thyroid peroxidase⁃a novel pathomechanism of chronic spontaneous urticaria?［J/OL］. PLoS One, 2011,6（4）:e14794. doi: 10.1371/journal.pone.0014794. |
| ［28］ | Atta AM, Rodrigues MZ, Sousa CP, et al. Autoantibody production in chronic idiopathic urticaria is not associated with helicobacter pylori infection［J］. Braz J Med Biol Res, 2004,37（1）:13⁃17. doi: 10.1590/s0100⁃879x2004000100002. |
| ［29］ | Concha LB, Chang CC, Szema AM, et al. IgE antithyroid antibodies in patients with Hashimoto′s disease and chronic urticaria［J］. Allergy Asthma Proc, 2004,25（5）:293⁃296. |
| ［30］ | Zhang L, Qiu L, Wu J, et al. IgE and IgG anti⁃thyroid autoantibodies in Chinese patients with chronic spontaneous urticaria and a literature review［J］. Allergy Asthma Immunol Res, 2022,14（1）:131⁃142. doi: 10.4168/aair.2022.14.1.131. |
| ［31］ | Sánchez J, Sánchez A, Cardona R. Causal relationship between anti⁃TPO IgE and chronic urticaria by in vitro and in vivo tests［J］. Allergy Asthma Immunol Res, 2019,11（1）:29⁃42. doi: 10. 4168/aair.2019.11.1.29. |
| ［32］ | Sánchez J, Sánchez A, Cardona R. Clinical characterization of patients with chronic spontaneous urticaria according to anti⁃TPO IgE levels［J］. J Immunol Res, 2019,2019:4202145. doi: 10.1155/2019/4202145. |
| ［33］ | Schmetzer O, Lakin E, Topal FA, et al. IL⁃24 is a common and specific autoantigen of IgE in patients with chronic spontaneous urticaria［J］. J Allergy Clin Immunol, 2018,142（3）:876⁃882. doi: 10.1016/j.jaci.2017.10.035. |
| ［34］ | Altrichter S, Zampeli V, Ellrich A, et al. IgM and IgA in addition to IgG autoantibodies against FcɛRIα are frequent and associated with disease markers of chronic spontaneous urticaria［J］. Allergy, 2020,75（12）:3208⁃3215. doi: 10.1111/all.14412. |
| ［35］ | Kolkhir P, Kovalkova E, Chernov A, et al. Autoimmune chronic spontaneous urticaria detection with IgG anti⁃TPO and total IgE［J］. J Allergy Clin Immunol Pract, 2021,9（11）:4138⁃4146.e8. doi: 10.1016/j.jaip.2021.07.043. |
| ［36］ | Johal KJ, Chichester KL, Oliver ET, et al. The efficacy of omalizumab treatment in chronic spontaneous urticaria is associated with basophil phenotypes［J］. J Allergy Clin Immunol, 2021,147（6）:2271⁃2280.e8. doi: 10.1016/j.jaci.2021.02.038. |
| ［37］ | O′Donnell BF, O′Neill CM, Francis DM, et al. Human leucocyte antigen classⅡ associations in chronic idiopathic urticaria［J］. Br J Dermatol, 1999,140（5）:853⁃858. doi: 10.1046/j.1365⁃2133.1999.02815.x. |
| ［38］ | Brzoza Z, Grzeszczak W, Rogala B, et al. PTPN22 polymorphism presumably plays a role in the genetic background of chronic spontaneous autoreactive urticaria［J］. Dermatology, 2012,224（4）:340⁃345. doi: 10.1159/000339332. |
| ［39］ | Sadr M, Khalili N, Mohebbi B, et al. Association of PTPN22 single nucleotide polymorphisms with chronic spontaneous urticaria［J］. Allergol Immunopathol （Madr）, 2021,49（2）:40⁃45. doi: 10.15586/aei.v49i2.53. |
| ［40］ | Zhang L, Qiu L, Wu J, et al. GWAS of Chronic spontaneous urticaria reveals genetic overlap with autoimmune diseases, not atopic diseases［J］. J Invest Dermatol, 2023,143（1）:67⁃77.e15. doi: 10.1016/j.jid.2022.07.012. |
| ［41］ | Qu S, Yang L, Liu Z. MicroRNA⁃194 reduces inflammatory response and human dermal microvascular endothelial cells permeability through suppression of TGF⁃β/SMAD pathway by inhibiting THBS1 in chronic idiopathic urticaria［J］. J Cell Biochem, 2020,121（1）:111⁃124. doi: 10.1002/jcb.28941. |
| ［42］ | Zhang L, Qi R, Yang Y, et al. Serum miR⁃125a⁃5p and CCL17 upregulated in chronic spontaneous urticaria and correlated with treatment response［J］. Acta Derm Venereol, 2019,99（6）:571⁃578. doi: 10.2340/00015555⁃3149. |
| ［43］ | Qi Y, Zhang L, Yang X, et al. Genome⁃wide DNA methylation profile in whole blood of patients with chronic spontaneous urticaria［J］. Front Immunol, 2021,12:681714. doi: 10.3389/fimmu.2021.681714. |
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