Chinese Journal of Dermatology ›› 2020, Vol. 53 ›› Issue (5): 394-397.doi: 10.35541/cjd.20190115

• Reviews • Previous Articles     Next Articles

Propionibacterium acnes: renaming and its correlation with acne vulgaris

Lang Dexiu, Liao Yong, Yang Rongya   

  1. Department of Dermatology, The Seventh Medical Center of PLA General Hospital, Beijing 100700, China
  • Received:2018-12-13 Revised:2019-09-27 Online:2020-05-15 Published:2020-04-30
  • Contact: Yang Rongya
  • Supported by:
    National Natural Science Foundation of China (81571972); Beijing New-star Plan of Science and Technology(Z161100004916139)

Abstract: 【Abstract】 Recently, biochemical and genomic studies have specified new classification methods and renamed Propionibacterium acnes as Cutibacterium acnes (C. acnes) to better study its phylotypes and distinguish it from other Propionibacterium species. C. acnes, an important commensal bacterium in human skin, is involved in maintaining skin health, and can also turn into an opportunistic pathogen causing acne vulgaris. Latest studies have showed that the balance between different phylotypes of C. acnes and its interaction with other microorganisms play a key role in the occurrence and development of acne vulgaris. This review summarizes correlations between C. acnes phylotypes and acne vulgaris, as well as antimicrobial susceptibility and interaction with other microorganism of C. acnes.

Key words: Acne vulgaris, Propionibacterium acnes, Bacterial typing techniques, Drug resistance, bacterial, Microbial interactions, Staphylococcus epidermidis, Bacteriophages, Cutibacterium acnes