关键词: 类天疱疮, 大疱性； 药物毒性； 疫苗； 二肽基肽酶Ⅳ抑制剂； 肿瘤坏死因子α； PD-1/PD-L1抑制剂

Abstract: 【Abstract】 Drug-induced bullous pemphigoid （BP） is a special type of BP, and is commonly induced by systemic or topical administration of drugs. For all the patients with newly emerging or rapidly aggravated BP, attention should be paid to the possibility of drug induction, especially vaccines and some novel drugs such as dipeptidyl-peptidase-4 inhibitors, tumor necrosis factor-α antagonist, and programmed death receptor-1/programmed death ligand-1 inhibitor, which have been frequently reported in recent years. This review summarizes research advances in drug-induced BP in recent years.

Key words: Pemphigoid, bullous, Drug toxicity, Vaccines, Dipeptidyl-peptidase IV inhibitors, Tumor necrosis factor-alpha, PD-1/PD-L1 inhibitor