| [1] | Ben Mordehai Y, Faibish H, Astman N, et al. Characteristics of patients with bullous pemphigoid: comparison of classic bullous pemphigoid to non⁃bullous pemphigoid[J]. J Eur Acad Dermatol Venereol, 2020,34(1):161⁃165. doi: 10.1111/jdv.15883. | 
																													
																						| [2] | Briand C, Gourier G, Poizeau F, et al. Characteristics of pruritus in bullous pemphigoid and impact on quality of life: a prospective cohort study[J]. Acta Derm Venereol, 2020,100(18):adv00320. doi: 10.2340/00015555⁃3683. | 
																													
																						| [3] | Hashimoto T, Kursewicz CD, Fayne RA, et al. Pathophysiologic mechanisms of itch in bullous pemphigoid[J]. J Am Acad Dermatol, 2020,83(1):53⁃62. doi: 10.1016/j.jaad.2019.07.060. | 
																													
																						| [4] | Ständer S, Hammers CM, Vorobyev A, et al. The impact of lesional inflammatory cellular infiltrate on the phenotype of bullous pemphigoid[J]. J Eur Acad Dermatol Venereol, 2021,35(8):1702⁃1711. doi: 10.1111/jdv.17303. | 
																													
																						| [5] | de Graauw E, Sitaru C, Horn M, et al. Evidence for a role of eosinophils in blister formation in bullous pemphigoid[J]. Allergy, 2017,72(7):1105⁃1113. doi: 10.1111/all.13131. | 
																													
																						| [6] | Simon D, Yousefi S, Cazzaniga S, et al. Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo⁃controlled, double⁃blind phase 2 pilot study[J]. Allergy, 2020,75(3):669⁃672. doi: 10.1111/all.13950. | 
																													
																						| [7] | Astra Zeneca. A study to investigate the use of benralizumab in patients with bullous pemphigoid[EB/OL].[2021⁃06⁃11]. https://clinicaltrials.gov/ct2/show/NCT04612790. | 
																													
																						| [8] | Barrios DM, Phillips GS, Geisler AN, et al. IgE blockade with omalizumab reduces pruritus related to immune checkpoint inhibitors and anti⁃HER2 therapies[J]. Ann Oncol, 2021,32(6):736⁃745. doi: 10.1016/j.annonc.2021.02.016. | 
																													
																						| [9] | Seyed Jafari SM, Gadaldi K, Feldmeyer L, et al. Effects of omalizumab on FcεRI and IgE expression in lesional skin of bullous pemphigoid[J]. Front Immunol, 2019,10:1919. doi: 10.3389/fimmu.2019.01919. | 
																													
																						| [10] | Seyed Jafari SM, Feldmeyer L, Bossart S, et al. Case report: combination of omalizumab and dupilumab for recalcitrant bullous pemphigoid[J]. Front Immunol, 2020,11:611549. doi: 10.3389/fimmu.2020.611549. | 
																													
																						| [11] | Wang F, Trier AM, Li F, et al. A basophil⁃neuronal axis promotes itch[J]. Cell, 2021,184(2):422⁃440.e17. doi: 10.1016/j.cell.2020.12.033. | 
																													
																						| [12] | Rüdrich U, Gehring M, Papakonstantinou E, et al. Eosinophils are a major source of interleukin⁃31 in bullous pemphigoid[J]. Acta Derm Venereol, 2018,98(8):766⁃771. doi: 10.2340/00015 555⁃2951. | 
																													
																						| [13] | Raap U, Gehring M, Kleiner S, et al. Human basophils are a source of ⁃ and are differentially activated by ⁃ IL⁃31[J]. Clin Exp Allergy, 2017,47(4):499⁃508. doi: 10.1111/cea.12875. | 
																													
																						| [14] | Maglie R, Ugolini F, De Logu F, et al. Overexpression of helper T cell type 2⁃related molecules in the skin of patients with eosinophilic dermatosis of hematologic malignancy[J]. J Am Acad Dermatol, 2021,doi: 10.1016/j.jaad.2021.07.007. | 
																													
																						| [15] | Egeberg A, Thyssen JP, Wu JJ. Anti⁃interleukin⁃31 receptor a antibody for atopic dermatitis[J]. N Engl J Med, 2017,376(21):2092⁃2093. doi: 10.1056/NEJMc1704013. | 
																													
																						| [16] | Kabashima K, Matsumura T, Komazaki H, et al. Trial of nemolizumab and topical agents for atopic dermatitis with pruritus[J]. N Engl J Med, 2020,383(2):141⁃150. doi: 10.1056/NEJMoa1917006. | 
																													
																						| [17] | Ständer S, Yosipovitch G, Legat FJ, et al. Trial of nemolizumab in moderate⁃to⁃severe prurigo nodularis[J]. N Engl J Med, 2020,382(8):706⁃716. doi: 10.1056/NEJMoa1908316. | 
																													
																						| [18] | Campion M, Smith L, Gatault S, et al. Interleukin⁃4 and interleukin⁃13 evoke scratching behaviour in mice[J]. Exp Dermatol, 2019,28(12):1501⁃1504. doi: 10.1111/exd.14034. | 
																													
																						| [19] | Abdat R, Waldman RA, de Bedout V, et al. Dupilumab as a novel therapy for bullous pemphigoid: a multicenter case series[J]. J Am Acad Dermatol, 2020,83(1):46⁃52. doi: 10.1016/j.jaad. 2020.01.089. | 
																													
																						| [20] | 杨璐, 曾跃平, 晋红中. 度普利尤单抗联合糖皮质激素治疗大疱性类天疱疮:国内首报并文献复习[J]. 中华临床免疫和变态反应杂志, 2021,15(1):47⁃52. doi: 10.3969/j.issn.1673⁃8705. 2021.01.009. | 
																													
																						| [21] | Kaye A, Gordon SC, Deverapalli SC, et al. Dupilumab for the treatment of recalcitrant bullous pemphigoid[J]. JAMA Dermatol, 2018,154(10):1225⁃1226. doi: 10.1001/jamadermatol.2018.2526. | 
																													
																						| [22] | Regeneron Pharmaceuticals. A study to evaluate the efficacy and safety of dupilumab in adult patients with bullous pemphigoid (LIBERTY⁃BP) [EB/OL].[2021⁃06⁃11]. https://www.ncbi.nlm.nih.gov/search/all/?term=NCT04206553. | 
																													
																						| [23] | Li SZ, Jin XX, Ge XL, et al. Thymic stromal lymphopoietin is implicated in the pathogenesis of bullous pemphigoid by dendritic cells[J]. J Immunol Res, 2020,2020:4594630. doi: 10.1155/2020/4594630. | 
																													
																						| [24] | Mishra SK, Wheeler JJ, Pitake S, et al. Periostin activation of integrin receptors on sensory neurons induces allergic itch[J]. Cell Rep, 2020,31(1):107472. doi: 10.1016/j.celrep.2020.03.036. | 
																													
																						| [25] | Mitamura Y, Nunomura S, Nanri Y, et al. The IL⁃13/periostin/IL⁃24 pathway causes epidermal barrier dysfunction in allergic skin inflammation[J]. Allergy, 2018,73(9):1881⁃1891. doi: 10.1111/all.13437. | 
																													
																						| [26] | Yosipovitch G, Ständer S, Kerby MB, et al. Serlopitant for the treatment of chronic pruritus: results of a randomized, multicenter, placebo⁃controlled phase 2 clinical trial[J]. J Am Acad Dermatol, 2018,78(5):882⁃891.e10. doi: 10.1016/j.jaad. 2018.02.030. | 
																													
																						| [27] | Ständer S, Kwon P, Hirman J, et al. Serlopitant reduced pruritus in patients with prurigo nodularis in a phase 2, randomized, placebo⁃controlled trial[J]. J Am Acad Dermatol, 2019,80(5):1395⁃1402. doi: 10.1016/j.jaad.2019.01.052. | 
																													
																						| [28] | Pariser DM, Bagel J, Lebwohl M, et al. Serlopitant for psoriatic pruritus: a phase 2 randomized, double⁃blind, placebo⁃controlled clinical trial[J]. J Am Acad Dermatol, 2020,82(6):1314⁃1320. doi: 10.1016/j.jaad.2020.01.056. |