中华皮肤科杂志 ›› 2019, Vol. 52 ›› Issue (5): 357-360.doi: 10.3760/cma.j.issn.0412-4030.2019.05.018

• 综述 • 上一篇    下一篇

肠道菌群与银屑病关系的研究进展

王丽玮    罗玲玲    崔盘根    李岷   

  1. 中国医学科学院  北京协和医学院  皮肤病医院皮肤科,南京  210042
  • 收稿日期:2018-05-15 修回日期:2019-02-27 出版日期:2019-05-15 发布日期:2019-04-30
  • 通讯作者: 崔盘根;李岷 E-mail:cuipangen@126.com; drlimin@sina.cn
  • 基金资助:
    中国医学科学院医学与健康科技创新工程项目(2017-I2M-1-017)

Relationship between intestinal flora and psoriasis

Wang Liwei, Luo Lingling, Cui Pan′gen, Li Min   

  1. Department of Dermatology, Hospital for Skin Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2018-05-15 Revised:2019-02-27 Online:2019-05-15 Published:2019-04-30
  • Contact: Cui Pan′gen; Li Min E-mail:cuipangen@126.com; drlimin@sina.cn
  • Supported by:
    CAMS Innovation Fund for Medical Sciences (2017-I2M-1-017)

摘要: 【摘要】 银屑病是一种慢性炎症性复发性皮肤病,发病机制至今尚未完全清楚,目前认为免疫、遗传及环境因素在其发病中起重要作用。越来越多研究证明,肠道菌群失调与免疫疾病有关,尤其与炎症性肠病关系密切。而银屑病与炎症性肠病发病机制及临床表现上有众多相似之处,肠道微生物群变化也被证实与银屑病有关。本文就银屑病与肠道菌群失调之间的可能关联展开讨论。

关键词: 银屑病, 肠道菌群失调

Abstract: 【Abstract】 Psoriasis is a chronic recurrent inflammatory skin disease, and its pathogenesis is still unclear. At present, it is believed that immune, genetic and environmental factors play important roles in the occurrence of psoriasis. More and more studies have indicated that the imbalance of intestinal flora is associated with immune diseases, especially inflammatory bowel disease. The pathogenesis and clinical manifestations of psoriasis are similar to those of inflammatory bowel disease, and psoriasis is proved to be associated with changes in intestinal microbial flora. This review discusses the association between the imbalance of intestinal flora and psoriasis.

Key words: Psoriasis, Imbalance of intestinal flora