雄激素性秃发与代谢综合征的关联：从发病机制到治疗策略

doi:10.35541/cjd.20240545

中华皮肤科杂志 ›› 2025, Vol. 58 ›› Issue (7): 591-594.doi: 10.35541/cjd.20240545

雄激素性秃发与代谢综合征的关联：从发病机制到治疗策略

林尽染,梁晓进,刘庆梅,吴文育

复旦大学附属华山医院皮肤科上海市皮肤病研究所，上海 200040

收稿日期:2024-10-12 修回日期:2025-05-12 发布日期:2025-07-03
通讯作者: 吴文育 E-mail:wenyu_wu@fudan.edu.cn
基金资助:
上海市自然科学基金（24ZR1408300）；上海市卫生健康领军人才项目（2022LJ017）；上海申康医院发展中心项目（SHDC22022302）；上海毛发医学工程技术研究中心项目（19DZ2250500）；上海市重中之重研究中心建设项目（2023ZZ02018）；上海市临床重点专科（shslczdzk01002）

Androgenetic alopecia and metabolic syndrome: from mechanisms to treatment strategies

Lin Jinran, Leong Hiochon, Liu Qingmei, Wu Wenyu

Lin Jinran, Leong Hiochon, Liu Qingmei, Wu Wenyu

Received:2024-10-12 Revised:2025-05-12 Published:2025-07-03
Contact: Wu Wenyu E-mail:wenyu_wu@fudan.edu.cn
Supported by:
Shanghai Natural Science Foundation（24ZR1408300）; Leading Talent Project of Shanghai Health Commission （2022LJ017）; Clinical Research Plan of Shanghai Hospital Development Center Foundation （SHDC22022302）; Shanghai Engineering Research Center of Hair Medicine （19DZ2250500）; Key Specialty Research Centre of Shanghai Health Commission （2023ZZ02018）; Shanghai Municipal Key Clinical Specialty （shslczdzk01002）

摘要/Abstract

摘要： 【摘要】雄激素性秃发是人类最常见的脱发类型，其主要特征为头皮毛囊的模式性微小化和毛发生长期的缩短。近年研究表明，雄激素性秃发与代谢综合征存在显著关联。代谢综合征的主要特征包括腹型肥胖、血糖异常、高血压和血脂异常。本文评估了雄激素性秃发与代谢综合征的流行病学关联，探讨其潜在并发机制，并分析现有和潜在的治疗策略。

关键词: 秃发, 雄激素性秃发, 代谢综合征, 胰岛素抵抗, 发生机制, 治疗

Abstract: 【Abstract】 Androgenetic alopecia （AGA） is the most common type of hair loss in humans, characterized by the patterned miniaturization of scalp hair follicles and shortened anagen phases. Recent studies have revealed a significant association between AGA and metabolic syndrome （MetS）. The hallmarks of MetS include abdominal obesity, impaired glucose metabolism, hypertension, and dyslipidemia. This commentary evaluates the epidemiological association between AGA and MetS, explores the underlying concurrent mechanisms, and discusses current and potential therapeutic strategies.

Key words: Alopecia, Androgenetic alopecia, Metabolic syndrome, Insulin resistance, Pathogenesis, Therapy

林尽染梁晓进刘庆梅吴文育. 雄激素性秃发与代谢综合征的关联：从发病机制到治疗策略[J]. 中华皮肤科杂志, 2025,58(7):591-594. doi:10.35541/cjd.20240545

Lin Jinran, Leong Hiochon, Liu Qingmei, Wu Wenyu. Androgenetic alopecia and metabolic syndrome: from mechanisms to treatment strategies[J]. Chinese Journal of Dermatology, 2025, 58(7): 591-594.doi:10.35541/cjd.20240545

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雄激素性秃发与代谢综合征的关联：从发病机制到治疗策略

Androgenetic alopecia and metabolic syndrome: from mechanisms to treatment strategies

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