痤疮发病相关的重要皮肤微生物群研究进展

doi:10.3760/cma.j.issn.0412-4030.2019.05.015

摘要/Abstract

摘要： 【摘要】皮肤微生物群在人出生后不久就开始形成，种类繁多、数量巨大，与皮肤健康密切相关。痤疮是一种微生物感染相关的常见皮肤病。痤疮丙酸杆菌、葡萄球菌属及马拉色菌属等是目前发现与痤疮发病最密切相关的3种微生物。本文综述上述3种微生物与痤疮发病的关系，主要包括不同型别细菌或真菌致病能力、与痤疮发病机制的关系及刺激机体产生免疫应答反应的差异等，以期为制定痤疮治疗的新策略提供依据。

关键词: 寻常痤疮, 微生物群落, 痤疮丙酸杆菌, 葡萄球菌属, 马拉色霉菌属

Abstract: 【Abstract】 Skin microbiota begin to form shortly after birth, with a wide variety and huge quantity, and are closely related to skin health. Acne is a common skin disorder associated with microbial infections. Propionibacterium acnes, Staphylococcus, Malassezia, etc., are three species of microorganisms currently known to be most closely associated with the occurrence of acne. This review summarizes the relationship between the above three species of microorganisms and the occurrence of acne, and mainly includes the pathogenicity of bacteria or fungi of different types, the relationship between these bacteria or fungi and the pathogenesis of acne, the difference in host immune responses induced by these bacteria or fungi, so as to provide evidence for developing new strategies for the treatment of acne.

Key words: Acne vulgaris, Microbial consortia, Propionibacterium acnes, Staphylococcus, Malassezia

刘宇甄曾荣徐浩翔李岷. 痤疮发病相关的重要皮肤微生物群研究进展[J]. 中华皮肤科杂志, 2019, 52(5): 346-349.

Liu Yuzhen, Zeng Rong, Xu Haoxiang, Li Min. Important skin microbiota associated with the occurrence of acne[J]. Chinese Journal of Dermatology, 2019, 52(5): 346-349.

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