中华皮肤科杂志 ›› 2019, Vol. 52 ›› Issue (3): 200-203.doi: 10.3760/cma.j.issn.0412-4030.2019.03.012
李晓雪 高星雅 蒋献
收稿日期:2018-03-06
修回日期:2018-11-21
发布日期:2019-03-04
通讯作者:
蒋献
E-mail:jennyxianj@163.com
Li Xiaoxue, Gao Xingya, Jiang Xian
Received:2018-03-06
Revised:2018-11-21
Published:2019-03-04
Contact:
Jiang Xian
E-mail:jennyxianj@163.com
摘要： 【摘要】 化学剥脱术是常用的三大皮肤重建术之一。α羟基酸、水杨酸、三氯醋酸和Jessner溶液是常用的化学剥脱剂，作用层次可从角质层达真皮网状层。化学剥脱术在皮肤科应用广泛，本文主要综述常用化学剥脱剂及化学剥脱术在痤疮、黄褐斑等损容性皮肤病及面部年轻化中的应用。
李晓雪 高星雅 蒋献. 化学剥脱术在损容性皮肤病及面部年轻化中的应用[J]. 中华皮肤科杂志, 2019,52(3):200-203. doi:10.3760/cma.j.issn.0412-4030.2019.03.012
Li Xiaoxue, Gao Xingya, Jiang Xian. Application of chemical peeling in discosmetic dermatoses and facial rejuvenation[J]. Chinese Journal of Dermatology, 2019, 52(3): 200-203.doi:10.3760/cma.j.issn.0412-4030.2019.03.012
| ［1］ | Weissler JM, Carney MJ, Carreras TJA, et al. The evolution of chemical peeling and modern⁃day applications［J］. Plast Reconstr Surg, 2017,140（5）:920⁃929. doi: 10.1097/PRS.000000000000 3787. |
| ［2］ | Vemula S, MBC M, Secemsky EA, et al. Assessing the safety of superficial chemical peels in darker skin: a retrospective study［J］. J Am Acad Dermatol, 2018,79（3）:508⁃513.e2. doi: 10.1016/ j.jaad.2018.02.064. |
| ［3］ | Bari AU, Iqbal Z, Rahman SB. Tolerance and safety of superficial chemical peeling with salicylic acid in various facial dermatoses［J］. Indian J Dermatol Venereol Leprol, 2005,71（2）:87⁃90. |
| ［4］ | Salam A, Dadzie OE, Galadari H. Chemical peeling in ethnic skin: an update［J］. Br J Dermatol, 2013,169 Suppl 3:82⁃90. doi: 10.1111/bjd.12535. |
| ［5］ | Hetter GP. An examination of the phenol⁃croton oil peel: Part I. Dissecting the formula［J］. Plast Reconstr Surg, 2000,105（1）:227⁃239; discussion 249⁃251. |
| ［6］ | Hetter GP. An examination of the phenol⁃croton oil peel: part IV. Face peel results with different concentrations of phenol and croton oil［J］. Plast Reconstr Surg, 2000,105（3）:1061⁃1083; discussion 1084⁃1087. |
| ［7］ | Zaenglein AL, Pathy AL, Schlosser BJ, et al. Guidelines of care for the management of acne vulgaris［J］. J Am Acad Dermatol, 2016,74（5）:945⁃973.e33. doi: 10.1016/j.jaad.2015.12.037. |
| ［8］ | Kessler E, Flanagan K, Chia C, et al. Comparison of alpha⁃ and beta⁃hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris［J］. Dermatol Surg, 2008,34（1）:45⁃50; discussion 51. doi: 10.1111/j.1524⁃4725.2007.34 007.x. |
| ［9］ | In JJ, Dong JH, Dong HK, et al. Comparative study of buffered 50 glycolic acid （pH 3.0） + 0.5 salicylic acid solution vs Jessner′s solution in patients with acne vulgaris［J］. J Cosmet Dermatol, 2018,17（5）:797⁃801. doi: 10.1111/jocd.12445. |
| ［10］ | Abdel MAM, Elaziz AADA, Omar H. Trichloroacetic acid versus salicylic acid in the treatment of acne vulgaris in dark⁃skinned patients［J］. Dermatol Surg, 2015,41（12）:1398⁃1404. doi: 10.1097/ DSS.0000000000000522. |
| ［11］ | Abdel HR, Hegazy R, Abdel HM, et al. Clinical and dermoscopic evaluation of combined （salicylic acid 20 and azelaic acid 20） versus trichloroacetic acid 25 chemical peel in acne: a RCT［J］. J Dermatolog Treat, 2018:1⁃22. doi: 10.1080/09546634. 2018.1484876. |
| ［12］ | Dayal S, Amrani A, Sahu P, et al. Jessner′s solution vs. 30 salicylic acid peels: a comparative study of the efficacy and safety in mild⁃to⁃moderate acne vulgaris［J］. J Cosmet Dermatol, 2017,16（1）:43⁃51. doi: 10.1111/jocd.12266. |
| ［13］ | Nofal E, Nofal A, Gharib K, et al. Combination chemical peels are more effective than single chemical peel in treatment of mild⁃to⁃moderate acne vulgaris: a split face comparative clinical trial［J］. J Cosmet Dermatol, 2018,17（5）:802⁃810. doi: 10.1111/jocd. 12763. |
| ［14］ | Bulbul BE, Tilki GI, Saricaoglu H. Efficacy of peeling during different periods of the menstrual cycle on acne［J］. J Cosmet Laser Ther, 2017,19（6）:373⁃375. doi: 10.1080/14764172.2017. 1334926. |
| ［15］ | Lee JB, Chung WG, Kwahck H, et al. Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method［J］. Dermatol Surg, 2002,28（11）:1017⁃1021; discussion 1021. |
| ［16］ | Nofal E, Helmy A, Nofal A, et al. Platelet⁃rich plasma versus CROSS technique with 100 trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study［J］. Dermatol Surg, 2014,40（8）:864⁃873. doi: 10.1111/dsu.0000000000000091. |
| ［17］ | El⁃Domyati M, Abdel⁃Wahab H, Hossam A. Microneedling combined with platelet⁃rich plasma or trichloroacetic acid peeling for management of acne scarring: a split⁃face clinical and histologic comparison［J］. J Cosmet Dermatol, 2018,17（1）:73⁃83. doi: 10.1111/jocd.12459. |
| ［18］ | Rana S, Mendiratta V, Chander R. Efficacy of microneedling with 70 glycolic acid peel vs microneedling alone in treatment of atrophic acne scars⁃A randomized controlled trial［J］. J Cosmet Dermatol, 2017,16（4）:454⁃459. doi: 10.1111/jocd.12377. |
| ［19］ | Taylor MB, Zaleski⁃Larsen L, McGraw TA. Single session treatment of rolling acne scars using tumescent anesthesia, 20 trichloracetic acid extensive subcision, and fractional CO2 laser［J］. Dermatol Surg, 2017,43 Suppl 1:S70⁃S74. doi: 10.1097/DSS.0000000000000895. |
| ［20］ | Kurokawa I, Oiso N, Kawada A. Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non⁃inflamed atrophic scars in acne vulgaris［J］. J Dermatol, 2017,44（4）:401⁃405. doi: 10.1111/1346⁃8138.13634. |
| ［21］ | Sarkar R, Arsiwala S, Dubey N, et al. Chemical peels in melasma: a review with consensus recommendations by Indian Pigmentary Expert Group［J］. Indian J Dermatol, 2017,62（6）:578⁃584. doi: 10.4103/ijd.IJD_490_17. |
| ［22］ | Sarkar R, Garg V, Bansal S, et al. Comparative evaluation of efficacy and tolerability of glycolic acid, salicylic mandelic acid, and phytic acid combination peels in melasma［J］. Dermatol Surg, 2016,42（3）:384⁃391. doi: 10.1097/DSS.0000000000000642. |
| ［23］ | Abdel⁃Meguid AM, Taha EA, Ismail SA. Combined Jessner solution and trichloroacetic acid versus trichloroacetic acid alone in the treatment of melasma in dark⁃skinned patients［J］. Dermatol Surg, 2017,43（5）:651⁃656. doi: 10.1097/DSS.000000 0000001036. |
| ［24］ | Saleh F, Moftah NH, Abdel⁃Azim E, et al. Q⁃switched Nd: YAG laser alone or with modified Jessner chemical peeling for treatment of mixed melasma in dark skin types: a comparative clinical, histopathological, and immunohistochemical study［J］. J Cosmet Dermatol, 2018,17（3）:319⁃327. doi: 10.1111/jocd. 12444. |
| ［25］ | Murtaza F, Bangash AR, Khushdil A, et al. Efficacy of trichloro⁃acetic acid peel alone versus combined topical magnesium ascorbyl phosphate for epidermal melasma［J］. J Coll Physicians Surg Pak, 2016,26（7）:557⁃561. doi: 2369. |
| ［26］ | Dayal S, Sahu P, Dua R. Combination of glycolic acid peel and topical 20 azelaic acid cream in melasma patients: efficacy and improvement in quality of life［J］. J Cosmet Dermatol, 2017,16（1）:35⁃42. doi: 10.1111/jocd.12260. |
| ［27］ | Balevi A, Ustuner P, Özdemir M. Salicylic acid peeling combined with vitamin C mesotherapy versus salicylic acid peeling alone in the treatment of mixed type melasma: a comparative study［J］. J Cosmet Laser Ther, 2017,19（5）:294⁃299. doi: 10.1080/14764172.2017.1314501. |
| ［28］ | Cohen PR. Melasma treatment with combined chemical peels and a novel topical agent containing an antiestrogen and a vascular endothelial growth factor inhibitor［J］. Dermatol Surg, 2018,44（4）:592⁃593. doi: 10.1097/DSS.0000000000001273. |
| ［29］ | Zaki NS, Hilal RF, Essam RM. Comparative study using fractional carbon dioxide laser versus glycolic acid peel in treatment of pseudo⁃acanthosis nigricans［J］. Lasers Med Sci, 2018,33（7）:1485⁃1491. doi: 10.1007/s10103⁃018⁃2505⁃x. |
| ［30］ | Sacchidanand S, Shetty AB, Leelavathy B. Efficacy of 15 trichloroacetic acid and 50 glycolic acid peel in the treatment of frictional melanosis: a comparative study［J］. J Cutan Aesthet Surg, 2015,8（1）:37⁃41. doi: 10.4103/0974⁃2077.155078. |
| ［31］ | Vavouli C, Katsambas A, Gregoriou S, et al. Chemical peeling with trichloroacetic acid and lactic acid for infraorbital dark circles［J］. J Cosmet Dermatol, 2013,12（3）:204⁃209. doi: 10. 1111/jocd.12044. |
| ［32］ | Ahmed NA, Mohammed SS, Fatani MI. Treatment of periorbital dark circles: comparative study of carboxy therapy vs chemical peeling vs mesotherapy［J］. J Cosmet Dermatol, 2019,18（1）:169⁃175. doi: 10.1111/jocd.12536. |
| ［33］ | Kontochristopoulos G, Kouris A, Platsidaki E, et al. Combination of microneedling and 10 trichloroacetic acid peels in the management of infraorbital dark circles［J］. J Cosmet Laser Ther, 2016,18（5）:289⁃292. doi: 10.3109/14764172.2016.1157363. |
| ［34］ | Butler PE, Gonzalez S, Randolph MA, et al. Quantitative and qualitative effects of chemical peeling on photo⁃aged skin: an experimental study［J］. Plast Reconstr Surg, 2001,107（1）:222⁃228. |
| ［35］ | Han SH, Kim HJ, Kim SY, et al. Skin rejuvenating effects of chemical peeling: a study in photoaged hairless mice［J］. Int J Dermatol, 2011,50（9）:1075⁃1082. doi: 10.1111/j.1365⁃4632. 2010.04712.x. |
| ［36］ | Wakade DV, Nayak CS, Bhatt KD. A study comparing the efficacy of monopolar radiofrequency and glycolic acid peels in facial rejuvenation of aging skin using histopathology and ultrabio⁃ microscopic sonography （UBM）⁃an evidence based study［J］. Acta Medica （Hradec Kralove）, 2016,59（1）:14⁃17. doi: 10.14712/ 18059694.2016.49. |
| ［37］ | Orra S, Waltzman JT, Mlynek K, et al. Periorbital phenol⁃croton oil chemical peel in conjunction with blepharoplasty: an evolving technique for periorbital facial rejuvenation ［J］. Plast Reconstr Surg, 2015,136（4S）:99⁃100. doi: 10.1097/01.prs.0000472401. 26529.67. |
| ［38］ | Tung R, Mahoney AM, Novice K, et al. Treatment of lateral canthal rhytides with a medium depth chemical peel with or without pretreatment with onabotulinum toxin type A: a randomized control trial［J］. Int J Womens Dermatol, 2016,2（1）:31⁃34. doi: 10.1016/j.ijwd.2015.12.006. |
| ［39］ | Sundaram H, Cegielska A, Wojciechowska A, et al. Prospective, randomized, investigator⁃blinded, split⁃face evaluation of a topical crosslinked hyaluronic acid serum for post⁃procedural improvement of skin quality and biomechanical attributes［J］. J Drugs Dermatol, 2018,17（4）:442⁃450. |
| ［40］ | O′Connor AA, Lowe PM, Shumack S, et al. Chemical peels: a review of current practice［J］. Australas J Dermatol, 2018,59（3）:171⁃181. doi: 10.1111/ajd.12715. |
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