中华皮肤科杂志 ›› 2024, e20220567.doi: 10.35541/cjd.20220567

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人工合成仿生纳米聚多巴胺黑色素在皮肤科的应用与展望

姜兆婷,坚哲   

  1. 空军军医大学西京皮肤医院,西安  710032
  • 收稿日期:2022-08-12 修回日期:2023-02-08 发布日期:2024-05-22
  • 通讯作者: 坚哲 E-mail:xjjianzhe@fmmu.edu.cn
  • 基金资助:
    国家自然科学基金(82373473、82173414);陕西省自然科学基金(2023-JC-ZD-44);空军军医大学人才扶持“凌云工程”项目(Axjhjz-102)

Application and prospect of artificial synthesized biomimetic polydopamine melanin nanoparticles in dermatology

Jiang Zhaoting, Jian Zhe   

  1. Department of Dermatology, Xijing Hospital, Air Force Medical University, Xi′an 710032, China
  • Received:2022-08-12 Revised:2023-02-08 Published:2024-05-22
  • Contact: Jian Zhe E-mail:xjjianzhe@fmmu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (81872521, 82173414); Key Projects of Shaanxi Natural Science Basic Research Program (2023-JC-ZD-44); Aoxiang Program in Lingyun Project of Air Force Military Medical University (Axjhjz-102)

摘要: 【摘要】 聚多巴胺是一种仿生纳米黑色素材料,由多巴胺自发聚合形成,黏附性和生物相容性较好。本文综述聚多巴胺的生物学特性及在伤口愈合、皮肤感染、防晒和辐射保护、皮肤肿瘤、色素减少性皮肤病中的应用,为未来利用聚多巴胺治疗皮肤病提供参考。

关键词: 黑素类, 多巴胺, 聚合物, 纳米结构, 仿生材料, 皮肤疾病

Abstract: 【Abstract】 Polydopamine is a biomimetic melanin-like nanomaterial, formed through the self-polymerization of dopamine in an alkaline environment. It possesses excellent adhesion properties and biocompatibility. This review summarizes the biological properties of polydopamine and its application in wound healing, skin infections, sun protection and radiation protection, skin tumors, and hypopigmented skin diseases, in order to provide a reference for the application of polydopamine in the treatment of skin diseases.

Key words: Melanins, Dopamine, Polymers, Nanostructures, Biomimetic materials, Skin diseases

引用本文

姜兆婷 坚哲. 人工合成仿生纳米聚多巴胺黑色素在皮肤科的应用与展望[J]. 中华皮肤科杂志, 2024,e20220567. doi:10.35541/cjd.20220567

Jiang Zhaoting, Jian Zhe. Application and prospect of artificial synthesized biomimetic polydopamine melanin nanoparticles in dermatology [J]. Chinese Journal of Dermatology,2024,e20220567. doi:10.35541/cjd.20220567