Chinese Journal of Dermatology ›› 2026, Vol. 59 ›› Issue (7): 611-618.doi: 10.35541/cjd.20250702

• Guidelines and Consensus • Previous Articles     Next Articles

Guideline for the clinical application of aminolevulinic acid-based photodynamic therapy in the treatment of condyloma acuminatum (2026 edition)

Photodynamic Therapy Research Cooperative Group, Chinese Society of Dermatology; Chinese Association of Rehabilitation Dermatology & Photodynamic Therapy; Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment   

  1. Photodynamic Therapy Research Cooperative Group, Chinese Society of Dermatology; Chinese Association of Rehabilitation Dermatology & Photodynamic Therapy; Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment
  • Received:2025-12-16 Revised:2026-05-13 Online:2026-07-15 Published:2026-07-03
  • Contact: Wang Xiuli; Gao Xinghua; Li Yuye E-mail:wangxiuli_1400023@tongji.edu.cn;gaobarry@hotmail.com; yyeli2000@126.com

Abstract: 【Abstract】 Aminolevulinic acid-based photodynamic therapy (ALA-PDT) has become a conventional treatment for condyloma acuminatum owing to its high cure rate, low recurrence rate, and mild adverse reactions. To further standardize, guide, and promote the clinical application of ALA-PDT in the management of condyloma acuminatum, this guideline provides standardized diagnostic and therapeutic recommendations from multiple aspects, including the mechanisms of action, treatment protocols, patient education before and after treatment, treatment course and follow-up, management of adverse reactions, combination with other therapeutic modalities, and treatment in special populations. Notably, a modified painless PDT protocol has been incorporated. This guideline is intended to serve as a practical reference for dermatologists, gynecologists, urologists, and proctologists, as well as nurses engaged in related clinical practice in China.

Key words: Condylomata acuminata, Therapy, Aminolevulinic acid-based photodynamic therapy, Guideline, Clinical application