Chinese Journal of Dermatology ›› 2024, e20230109.doi: 10.35541/cjd.20230109
• Reviews • Previous Articles Next Articles
Yan Kexin, Xu Xiulian
Received:2023-02-28
Revised:2023-12-09
Online:2024-01-29
Published:2024-03-11
Contact:
Xu Xiulian
E-mail:xxlqjl@sina.com
Supported by:Yan Kexin, Xu Xiulian. Nanomedicine: a new strategy for the diagnosis and treatment of melanoma[J]. Chinese Journal of Dermatology,2024,e20230109. doi:10.35541/cjd.20230109
| [1] | Yang K, Oak A, Slominski RM, et al. Current molecular markers of melanoma and treatment targets[J]. Int J Mol Sci, 2020,21(10):3535. doi: 10.3390/ijms21103535. |
| [2] | Al⁃Zoubi MS, Al⁃Zoubi RM. Nanomedicine tactics in cancer treatment: challenge and hope[J]. Crit Rev Oncol Hematol, 2022,174:103677. doi: 10.1016/j.critrevonc.2022.103677. |
| [3] | Peng S, Xiao F, Chen M, et al. Tumor⁃microenvironment⁃responsive nanomedicine for enhanced cancer immunotherapy[J]. Adv Sci (Weinh), 2022,9(1):e2103836. doi: 10.1002/advs. 202103836. |
| [4] | Farjadian F, Ghasemi A, Gohari O, et al. Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities[J]. Nanomedicine (Lond), 2019,14(1):93⁃126. doi: 10.2217/nnm⁃2018⁃0120. |
| [5] | Wang P, Yang W, Shen S, et al. Differential diagnosis and precision therapy of two typical malignant cutaneous tumors leveraging their tumor microenvironment: a photomedicine strategy[J]. ACS Nano, 2019,13(10):11168⁃11180. doi: 10.1021/ acsnano.9b04070. |
| [6] | Portilho FL, Helal⁃Neto E, Cabezas SS, et al. Magnetic core mesoporous silica nanoparticles doped with dacarbazine and labelled with 99mTc for early and differential detection of metastatic melanoma by single photon emission computed tomography[J]. Artif Cells Nanomed Biotechnol, 2018,46(sup1):1080⁃1087. doi: 10.1080/21691401.2018.1443941. |
| [7] | Zou Y, Wei Y, Sun Y, et al. Cyclic RGD⁃functionalized and disulfide⁃crosslinked iodine⁃rich polymersomes as a robust and smart theranostic agent for targeted CT imaging and chemotherapy of tumor[J]. Theranostics, 2019,9(26):8061⁃8072. doi: 10.7150/thno.37184. |
| [8] | Qiu X, Wu X, Fang X, et al. Raman spectroscopy combined with deep learning for rapid detection of melanoma at the single cell level[J]. Spectrochim Acta A Mol Biomol Spectrosc, 2023,286:122029. doi: 10.1016/j.saa.2022.122029. |
| [9] | Zhang Y, Takahashi Y, Hong SP, et al. High⁃resolution label⁃free 3D mapping of extracellular pH of single living cells[J]. Nat Commun, 2019,10(1):5610. doi: 10.1038/s41467⁃019⁃13535⁃1. |
| [10] | Ou YC, Wen X, Johnson CA, et al. Multimodal multiplexed immunoimaging with nanostars to detect multiple immuno⁃markers and monitor response to immunotherapies[J]. ACS Nano, 2020,14(1):651⁃663. doi: 10.1021/acsnano.9b07326. |
| [11] | Jenkins RW, Fisher DE. Treatment of advanced melanoma in 2020 and beyond[J]. J Invest Dermatol, 2021,141(1):23⁃31. doi: 10.1016/j.jid.2020.03.943. |
| [12] | Carlino MS, Larkin J, Long GV. Immune checkpoint inhibitors in melanoma[J]. Lancet, 2021,398(10304):1002⁃1014. doi: 10. 1016/S0140⁃6736(21)01206⁃X. |
| [13] | Yang X, Fan J, Wu Y, et al. Synthetic multiepitope neoantigen DNA vaccine for personalized cancer immunotherapy[J]. Nanomedicine, 2021,37:102443. doi: 10.1016/j.nano.2021.102443. |
| [14] | Hu M, Zhang J, Kong L, et al. Immunogenic hybrid nanovesicles of liposomes and tumor⁃derived nanovesicles for cancer immunochemotherapy[J]. ACS Nano, 2021,15(2):3123⁃3138. doi: 10.1021/acsnano.0c09681. |
| [15] | Salotto KE, Olson WC Jr, Pollack KE, et al. A nano⁃enhanced vaccine for metastatic melanoma immunotherapy[J]. Cancer Drug Resist, 2022,5(3):829⁃845. doi: 10.20517/cdr.2021.132. |
| [16] | Sun Y, Lu D, Yin Y, et al. PTENα functions as an immune suppressor and promotes immune resistance in PTEN⁃mutant cancer[J]. Nat Commun, 2021,12(1):5147. doi: 10.1038/s41467⁃021⁃25417⁃6. |
| [17] | Lin YX, Wang Y, Ding J, et al. Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models[J]. Sci Transl Med, 2021,13(599):eaba9772. doi: 10.1126/scitranslmed.aba9772. |
| [18] | Christofides A, Strauss L, Yeo A, et al. The complex role of tumor⁃infiltrating macrophages[J]. Nat Immunol, 2022,23(8):1148⁃1156. doi: 10.1038/s41590⁃022⁃01267⁃2. |
| [19] | Rao L, Zhao SK, Wen C, et al. Activating macrophage⁃mediated cancer immunotherapy by genetically edited nanoparticles[J]. Adv Mater, 2020,32(47):e2004853. doi: 10.1002/adma.202004853. |
| [20] | Guo W, Wang H, Li C. Signal pathways of melanoma and targeted therapy[J]. Signal Transduct Target Ther, 2021,6(1):424. doi: 10.1038/s41392⁃021⁃00827⁃6. |
| [21] | Epshtein Y, Blau R, Pisarevsky E, et al. Polyglutamate⁃based nanoconjugates for image⁃guided surgery and post⁃operative melanoma metastases prevention[J]. Theranostics, 2022,12(14):6339⁃6362. doi: 10.7150/thno.72941. |
| [22] | Zhang MJ, Liang MY, Yang SC, et al. Bioengineering of BRAF and COX2 inhibitor nanogels to boost the immunotherapy of melanoma via pyroptosis[J]. Chem Commun (Camb), 2023,59(7):932⁃935. doi: 10.1039/d2cc05498a. |
| [23] | Pisarevsky E, Blau R, Epshtein Y, et al. Rational design of polyglutamic acid delivering an optimized combination of drugs targeting mutated BRAF and MEK in melanoma[J]. Adv Ther (Weinh), 2020,3(8):2000028 [pii]. doi: 10.1002/adtp.202000028. |
| [24] | Shinkuma S. Advances in gene therapy and their application to skin diseases: a review[J]. J Dermatol Sci, 2021,103(1):2⁃9. doi: 10.1016/j.jdermsci.2021.05.004. |
| [25] | Liu J, Yang L, Yuan X, et al. Targeted nanotherapeutics using LACTB gene therapy against melanoma[J]. Int J Nanomedicine, 2021,16:7697⁃7709. doi: 10.2147/IJN.S331519. |
| [26] | Ma Y, Lin H, Wang P, et al. A miRNA⁃based gene therapy nanodrug synergistically enhances pro⁃inflammatory antitumor immunity against melanoma[J]. Acta Biomater, 2023,155:538⁃553. doi: 10.1016/j.actbio.2022.11.016. |
| [27] | Zhang X, Cai A, Gao Y, et al. Treatment of melanoma by nano⁃conjugate⁃delivered wee1 siRNA[J]. Mol Pharm, 2021,18(9):3387⁃3400. doi: 10.1021/acs.molpharmaceut.1c00316. |
| [28] | Zhang Z, Xu D, Wang J, et al. Rolling circle amplification⁃based dna nano⁃assembly for targeted drug delivery and gene therapy[J]. Biomacromolecules, 2023,24(1):439⁃448. doi: 10.1021/acs. biomac.2c01271. |
| [29] | Zahraie N, Perota G, Dehdari Vais R, et al. Simultaneous chemotherapy/sonodynamic therapy of the melanoma cancer cells using a gold⁃paclitaxel nanostructure[J]. Photodiagnosis Photodyn Ther, 2022,39:102991. doi: 10.1016/j.pdpdt.2022. 102991. |
| [30] | Bhattarai RS, Bariwal J, Kumar V, et al. pH⁃sensitive nanomedicine of novel tubulin polymerization inhibitor for lung metastatic melanoma[J]. J Control Release, 2022,350:569⁃583. doi: 10.1016/j.jconrel.2022.08.023. |
| [31] | Li A, Zhao J, Fu J, et al. Recent advances of biomimetic nano⁃systems in the diagnosis and treatment of tumor[J]. Asian J Pharm Sci, 2021,16(2):161⁃174. doi: 10.1016/j.ajps.2019.08. 001. |
| [32] | Molinaro R, Martinez JO, Zinger A, et al. Leukocyte⁃mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma[J]. Biomater Sci, 2020,8(1):333⁃341. doi: 10.1039/c9bm01766f. |
| [33] | Wu M, Mei T, Lin C, et al. Melanoma cell membrane biomimetic versatile cus nanoprobes for homologous targeting photoacoustic imaging and photothermal chemotherapy[J]. ACS Appl Mater Interfaces, 2020,12(14):16031⁃16039. doi: 10.1021/acsami. 9b23177. |
| [34] | Naidoo C, Kruger CA, Abrahamse H. Photodynamic therapy for metastatic melanoma treatment: a review[J]. Technol Cancer Res Treat, 2018,17:15330338 18791795. doi: 10.1177/1533033 818791795. |
| [35] | Huang X, Mu N, Ding Y, et al. Targeted delivery and enhanced uptake of chemo⁃photodynamic nanomedicine for melanoma treatment[J]. Acta Biomater, 2022,147:356⁃365. doi: 10.1016/j.actbio.2022.05.015. |
| [36] | Bian Q, Huang L, Xu Y, et al. A facile low⁃dose photosensitizer⁃incorporated dissolving microneedles⁃based composite system for eliciting antitumor immunity and the abscopal effect[J]. ACS Nano, 2021,15(12):19468⁃19479. doi: 10.1021/acsnano. 1c06225. |
| [37] | Wang Y, Zhao Z, Liu C, et al. B16 membrane⁃coated vesicles for combined photodynamic therapy and immunotherapy shift immune microenvironment of melanoma[J]. Int J Nanomedicine, 2022,17:855⁃868. doi: 10.2147/IJN.S338488. |
| [38] | Hou X, Tao Y, Li X, et al. CD44⁃targeting oxygen self⁃sufficient nanoparticles for enhanced photodynamic therapy against malignant melanoma[J]. Int J Nanomedicine, 2020,15:10401⁃10416. doi: 10.2147/IJN.S283515. |
| [39] | Zhao L, Zhang X, Wang X, et al. Recent advances in selective photothermal therapy of tumor[J]. J Nanobiotechnology, 2021,19(1):335. doi: 10.1186/s12951⁃021⁃01080⁃3. |
| [40] | S M, E S, R DV, et al. Phototherapy and sonotherapy of melanoma cancer cells using nanoparticles of selenium⁃polyethylene glycol⁃curcumin as a dual⁃mode sensitizer[J]. J Biomed Phys Eng, 2020,10(5):597⁃606. doi: 10.31661/jbpe.v0i0.1912⁃1039. |
| [41] | Soratijahromi E, Mohammadi S, Dehdari Vais R, et al. Photothermal/sonodynamic therapy of melanoma tumor by a gold/manganese dioxide nanocomposite: in vitro and in vivo studies[J]. Photodiagnosis Photodyn Ther, 2020,31:101846. doi: 10. 1016/j.pdpdt.2020.101846. |
| [42] | Wang S, Ma Z, Shi Z, et al. Chidamide stacked in magnetic polypyrrole nano⁃composites counter thermotolerance and metastasis for visualized cancer photothermal therapy[J]. Drug Deliv, 2022,29(1):1312⁃1325. doi: 10.1080/10717544.2022. 2068697. |
| [43] | Heshmati Aghda N, Torres Hurtado S, Abdulsahib SM, et al. Dual photothermal/chemotherapy of melanoma cells with albumin nanoparticles carrying indocyanine green and doxorubicin leads to immunogenic cell death[J]. Macromol Biosci, 2022,22(2):e2100353. doi: 10.1002/mabi.202100353. |
| [44] | Baskar R, Lee KA, Yeo R, et al. Cancer and radiation therapy: current advances and future directions[J]. Int J Med Sci, 2012,9(3):193⁃199. doi: 10.7150/ijms.3635. |
| [45] | Chen MH, Lee CH, Liang HK, et al. Integrating the microneedles with carboplatin to facilitate the therapeutic effect of radiotherapy for skin cancers[J]. Biomater Adv, 2022,141:213113. doi: 10.1016/j.bioadv.2022.213113. |
| [46] | Chan L, Gao P, Zhou W, et al. Sequentially triggered delivery system of black phosphorus quantum dots with surface charge⁃switching ability for precise tumor radiosensitization[J]. ACS Nano, 2018,12(12):12401⁃12415. doi: 10.1021/acsnano.8b06483. |
| [1] | Liu Houguang, Shen Yi, Wei Qiongling, Li Zheng, Huo Shanshan, Xie Guangcheng, Liu Yingwen. Effect of overexpression or inhibition of cyclin-dependent kinase 2 on the metabolome of A375 cells [J]. Chinese Journal of Dermatology, 2026, 59(1): 51-58. |
| [2] | Jiang Jiayi, Wang Daguang. Prevention and management of thrombus during the perioperative period in dermatologic surgery [J]. Chinese Journal of Dermatology, 2026, 59(1): 85-88. |
| [3] | Chen Yanyan, Zhang Hanlin, Liu Liping, Li Yumei. Correlations between circadian rhythm and melanoma [J]. Chinese Journal of Dermatology, 2026, 59(1): 82-85. |
| [4] | Writing committee of “Chinese expert consensus on the diagnosis and treatment of scabies ( edition)”. Chinese expert consensus on the diagnosis and treatment of scabies (2026 edition) [J]. Chinese Journal of Dermatology, 2026, 59(1): 1-8. |
| [5] | Xiang Leihong, Xu Zhongyi . Diagnosis and treatment of acquired dermal macular hyperpigmentation: challenges and strategies [J]. Chinese Journal of Dermatology, 2026, 59(1): 74-76. |
| [6] | Chinese Society of Dermatology, China Dermatologist Association, Combination of Traditional and Western Medicine Dermatology, Chinese Non-Government Dermatologist Institutions Association. Expert consensus on educational guidance for rosacea patients(2025) [J]. Chinese Journal of Dermatology, 2026, 0(1): 20240725-e20240725. |
| [7] | Dai Yeqin, Song Xiuzu. Application of hair follicle transplantation and follicular cell suspension transplantation in the treatment of vitiligo [J]. Chinese Journal of Dermatology, 2025, 58(9): 882-885. |
| [8] | Zhou Miaoni, Sheng Anqi, Fu Lifang, Jin Rong, Xu Wen, Wei Xiaodong, Xu Ai′e . Efficacy and safety of an antioxidant gel containing tea polyphenols combined with narrow-band ultraviolet B in the treatment of vitiligo: a single-center randomized controlled trial [J]. Chinese Journal of Dermatology, 2025, 58(9): 834-838. |
| [9] | Xu Zhongyi, Xing Xiaoxue, Dong Yaqi, Zhang Chengfeng, Xiang Leihong. Retrospective analysis of clinical manifestations and treatment outcomes in 254 patients with melasma in a tertiary grade-A hospital in Shanghai [J]. Chinese Journal of Dermatology, 2025, 58(9): 808-815. |
| [10] | Jiang Ziqi, Zhong Judan, Chen Tingqiao, Chen Jin. Pathogenesis and treatment of melasma [J]. Chinese Journal of Dermatology, 2025, 58(9): 868-872. |
| [11] | Zhong Jiemin, Li Wei, Zhang Shujuan, Yang Yan, Xue Rujun, Li Xinyi, Ke Yanan, Chen Xiaoyin, Chen Quan. Comparison of the efficacy and safety of nanomicroneedle- versus ultrasound-mediated delivery of tranexamic acid for the treatment of melasma: a randomized controlled study [J]. Chinese Journal of Dermatology, 2025, 58(9): 829-833. |
| [12] | Guliziba·Tuersun, Zhao Yanan, Wang Hongjuan, Kang Xiaojing, Qu Yuanyuan. Efficacy of autologous melanocyte transplantation combined with 308-nm light-emitting diode phototherapy at escalating doses in the treatment of refractory stable vitiligo: a clinical observation [J]. Chinese Journal of Dermatology, 2025, 58(9): 852-856. |
| [13] | Jiang Qian, Hu Bin, Chen Yao, Chen Liuqing. Acquired facial hyperpigmented macules in children: a retrospective analysis of clinical and skin imaging features in 131 cases [J]. Chinese Journal of Dermatology, 2025, 58(9): 843-847. |
| [14] | Luo Shuaihantian, Long Hai, Lu Qianjin. Research advances in systemic lupus erythematosus in 2024 [J]. Chinese Journal of Dermatology, 2025, 58(8): 777-780. |
| [15] | Bai Qi, Zhu Mingfang, Wu Qingting, Ji Xiaotian, Yang Huiyi, Ma Liping, Zhou Jiaxin. Effect of sinomenine on skin lesions in 2,4-dinitrochlorobenzene-induced atopic dermatitis-like mouse models [J]. Chinese Journal of Dermatology, 2025, 58(8): 759-766. |
|