Abstract: 【Abstract】 Actinic keratosis is a chronic and progressive precancerous disease, which may develop into cutaneous squamous cell carcinoma. With the gradual increase in the number of patients with actinic keratosis in China, there is an urgent need to establish appropriate diagnostic and treatment standards. Therefore, Chinese Association of Rehabilitation Dermatology, Chinese Society of Dermatology and Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment organized relevant experts on actinic keratosis to formulate a consensus on clinical diagnosis and treatment of actinic keratosis in China based on Chinese and international literature, international guidelines on actinic keratosis, clinical experience, as well as current status of diagnosis and treatment of actinic keratosis in China. This consensus elaborates on epidemiology, pathogenic factors and clinical outcomes, clinical manifestations and classification, diagnosis and differential diagnosis, and treatment strategies of actinic keratosis, as well as patient education. Besides histopathology, newly developed dermoscopy and reflectance confocal microscopy are also included in the diagnostic methods. Treatment strategies include common topical treatments (including photodynamic therapy, topical drugs, physical therapy, and surgical resection)and systemic treatments, and recommendations are formulated according to the level of evidence. It is hoped that this consensus can provide a reference for dermatologists in the management of actinic keratosis.

Key words: Keratosis, actinic, Diagnosis, Therapeutics, Expert consensus