Chinese Journal of Dermatology ›› 2024, Vol. 57 ›› Issue (5): 409-417.doi: 10.35541/cjd.20230570
• Guidelines and Consensus • Previous Articles Next Articles
China Dermatologist Association; Combination of Traditional and Western Medicine Dermatology
Received:
2023-10-07
Revised:
2024-03-22
Online:
2024-05-15
Published:
2024-04-30
Contact:
Shi Yuling;Wang Gang; Gu Jun
E-mail:shiyuling1973@tongji.edu.cn;xjwgang@ fmmu.edu.cn;gujun79@163.com
Supported by:
China Dermatologist Association, Combination of Traditional and Western Medicine Dermatology. Diagnosis and treatment of erythrodermic psoriasis: a Chinese expert consensus statement (2024)[J]. Chinese Journal of Dermatology, 2024, 57(5): 409-417.doi:10.35541/cjd.20230570
[1] | Lo Y, Tsai TF. Updates on the treatment of erythrodermic psoriasis[J]. Psoriasis (Auckl), 2021,11:59⁃73. doi: 10.2147/PTT.S288345. |
[2] | 全国银屑病流行调查组. 全国1984年银屑病流行调查报告[J]. 中华皮肤科杂志, 1986,19(5):253⁃261. |
[3] | Ding X, Wang T, Shen Y, et al. Prevalence of psoriasis in China: a population⁃based study in six cities[J]. Eur J Dermatol, 2012,22(5):663⁃667. doi: 10.1684/ejd.2012.1802. |
[4] | Rosenbach M, Hsu S, Korman NJ, et al. Treatment of erythrodermic psoriasis: from the medical board of the National Psoriasis Foundation[J]. J Am Acad Dermatol, 2010,62(4):655⁃662. doi: 10.1016/j.jaad.2009.05.048. |
[5] | Sigurdsson V, Steegmans PH, van Vloten WA. The incidence of erythroderma: a survey among all dermatologists in The Netherlands[J]. J Am Acad Dermatol, 2001,45(5):675⁃678. doi: 10.1067/mjd.2001.116224. |
[6] | Yan D, Afifi L, Jeon C, et al. A cross⁃sectional study of the distribution of psoriasis subtypes in different ethno⁃racial groups[J]. Dermatol Online J, 2018,24(7):13030/qt5z21q4k2 [pii]. |
[7] | Hawilo A, Zaraa I, Benmously R, et al. Erythrodermic psoriasis: epidemiological clinical and therapeutic features about 60 cases[J]. Tunis Med, 2011,89(11):841⁃847. |
[8] | Chang SE, Choi JH, Koh JK. Congenital erythrodermic psoriasis[J]. Br J Dermatol, 1999,140(3):538⁃539. doi: 10.1046/j.1365⁃2133.1999.02725.x. |
[9] | Goeckerman WH, O′Leary PA. Erythroderma psoriaticum: a review of twenty⁃two cases[J]. JAMA,1932,99 (25): 2102⁃2105. doi: 10.1001/jama.1932.02740770032007. |
[10] | Boyd AS, Menter A. Erythrodermic psoriasis. Precipitating factors, course, and prognosis in 50 patients[J]. J Am Acad Dermatol, 1989,21(5 Pt 1):985⁃991. |
[11] | Heinecke G, Lebwohl M. Erythroderma.In: Buka B, Uliasz A, Krishnamurthy K. Buka′s Emergencies in Dermatology[M]. New York: Springer, 2013:133⁃145. doi: 10.1007/978⁃1⁃4614⁃5031⁃3_7. |
[12] | Carrasquillo OY, Pabón⁃Cartagena G, Falto⁃Aizpurua LA, et al. Treatment of erythrodermic psoriasis with biologics: a systematic review[J]. J Am Acad Dermatol, 2020,83(1):151⁃158. doi: 10.1016/j.jaad.2020.03.073. |
[13] | Ogawa K, Okada Y. The current landscape of psoriasis genetics in 2020[J]. J Dermatol Sci, 2020,99(1):2⁃8. doi: 10.1016/j.jdermsci.2020.05.008. |
[14] | Chen L, Tsai TF. HLA⁃Cw6 and psoriasis[J]. Br J Dermatol, 2018,178(4):854⁃862. doi: 10.1111/bjd.16083. |
[15] | Ikäheimo I, Tiilikainen A, Karvonen J, et al. HLA risk haplotype Cw6,DR7,DQA1*0201 and HLA⁃Cw6 with reference to the clinical picture of psoriasis vulgaris[J]. Arch Dermatol Res, 1996,288(7):363⁃365. doi: 10.1007/BF02507104. |
[16] | Li X, Chen M, Fu X, et al. Mutation analysis of the IL36RN gene in Chinese patients with generalized pustular psoriasis with/without psoriasis vulgaris[J]. J Dermatol Sci, 2014,76(2):132⁃138. doi: 10.1016/j.jdermsci.2014.08.007. |
[17] | Fu F, Sun Y, Zhao Q, et al. Rare CARD14 missense variants associated with palmoplantar pustulosis (PPP) in the Chinese Han population[J]. Eur J Dermatol, 2019,29(1):99⁃100. doi: 10.1684/ejd.2018.3457. |
[18] | Lo Y, Chiu HY, Tsai TF. Clinical features and genetic polymorphism in Chinese patients with erythrodermic psoriasis in a single dermatologic clinic[J]. Mol Diagn Ther, 2020,24(1):85⁃93. doi: 10.1007/s40291⁃019⁃00441⁃x. |
[19] | Signa S, Campione E, Rusmini M, et al. Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumab[J]. Pediatr Rheumatol Online J, 2019,17(1):38. doi: 10.1186/s12969⁃019⁃0336⁃3. |
[20] | Piccirillo F, Stinco G, Patrone P. Erythrodermic psoriasis successfully treated with efalizumab[J]. Eur J Dermatol, 2008,18(3):357⁃358. doi: 10.1684/ejd.2008.0417. |
[21] | Kano Y, Teraki Y, Shiohara T. Dramatic improvement of psoriatic erythroderma after acute hepatitis: analysis of cytokine synthesis capability in peripheral blood T cells[J]. Br J Dermatol, 2006,155(2):455⁃459. doi: 10.1111/j.1365⁃2133. 2006.07270.x. |
[22] | Wang H, Wang S, Li L, et al. Involvement of the cytokine TWEAK in the pathogenesis of psoriasis vulgaris, pustular psoriasis, and erythrodermic psoriasis[J]. Cytokine, 2021,138:155391. doi: 10.1016/j.cyto.2020.155391. |
[23] | Ma AR, Liu F, Wang R, et al. Prevalence of metabolic syndrome in Chinese patients with erythrodermic psoriasis: a case⁃control study[J]. Front Endocrinol (Lausanne), 2021,12:677912. doi: 10.3389/fendo.2021.677912. |
[24] | Zheng J, Gao Y, Liu N, et al. Higher prevalence of thyroid dysfunction in patients with erythrodermic psoriasis[J]. J Dermatol, 2020,47(9):1007⁃1012. doi: 10.1111/1346⁃8138. 15427. |
[25] | Zhang L, Xue S, Yu J, et al. IgA nephropathy associated with erythrodermic psoriasis: a case report[J]. Medicine (Baltimore), 2019,98(19):e15433. doi: 10.1097/MD.0000000000015433. |
[26] | Ye F, Gui X, Wu C, et al. Severity evaluation and prognostic factors in erythrodermic psoriasis[J]. Eur J Dermatol, 2018,28(6):851⁃853. doi: 10.1684/ejd.2018.3437. |
[27] | Tso S, Satchwell F, Moiz H, et al. Erythroderma (exfoliative dermatitis). Part 1: underlying causes, clinical presentation and pathogenesis[J]. Clin Exp Dermatol, 2021,46(6):1001⁃1010. doi: 10.1111/ced.14625. |
[28] | 中华医学会皮肤性病学分会. 阿维A治疗银屑病专家共识(2017版)[J]. 中华皮肤科杂志, 2017,50(6):397⁃399. doi: 10.3760/cma.j.issn.0412⁃4030.2017.06.002. |
[29] | Ling MR. Acitretin: optimal dosing strategies[J]. J Am Acad Dermatol, 1999,41(3 Pt 2):S13⁃17. doi: 10.1016/s0190⁃9622(99)70360⁃9. |
[30] | 中华医学会皮肤性病学分会银屑病专业委员会. 中国银屑病诊疗指南(2023版)[J]. 中华皮肤科杂志, 2023,56(7):573⁃625. doi: 10.35541/cjd.20220839. |
[31] | Soleymani T, Vassantachart JM, Wu JJ. Comparison of guidelines for the use of cyclosporine for psoriasis: a critical appraisal and comprehensive review[J]. J Drugs Dermatol, 2016,15(3):293⁃301. |
[32] | Bruzzese V, Pepe J. Efficacy of cyclosporine in the treatment of a case of infliximab⁃induced erythrodermic psoriasis[J]. Int J Immunopathol Pharmacol, 2009,22(1):235⁃238. doi: 10.1177/039463200902200126. |
[33] | Esposito M, Mazzotta A, de Felice C, et al. Treatment of erythrodermic psoriasis with etanercept[J]. Br J Dermatol, 2006,155(1):156⁃159. doi: 10.1111/j.1365⁃2133.2006.07217.x. |
[34] | Viguier M, Pagès C, Aubin F, et al. Efficacy and safety of biologics in erythrodermic psoriasis: a multicentre, retrospective study[J]. Br J Dermatol, 2012,167(2):417⁃423. doi: 10.1111/j.1365⁃2133.2012.10940.x. |
[35] | Damiani G, Pacifico A, Russo F, et al. Use of secukinumab in a cohort of erythrodermic psoriatic patients: a pilot study[J]. J Clin Med, 2019,8(6):770. doi: 10.3390/jcm8060770. |
[36] | Saeki H, Nakagawa H, Ishii T, et al. Efficacy and safety of open⁃label ixekizumab treatment in Japanese patients with moderate⁃to⁃severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis[J]. J Eur Acad Dermatol Venereol, 2015,29(6):1148⁃1155. doi: 10.1111/jdv.12773. |
[37] | Okubo Y, Mabuchi T, Iwatsuki K, et al. Long⁃term efficacy and safety of ixekizumab in Japanese patients with erythrodermic or generalized pustular psoriasis: subgroup analyses of an open⁃label, phase 3 study (UNCOVER⁃J)[J]. J Eur Acad Dermatol Venereol, 2019,33(2):325⁃332. doi: 10.1111/jdv.15287. |
[38] | Yamasaki K, Nakagawa H, Kubo Y, et al. Efficacy and safety of brodalumab in patients with generalized pustular psoriasis and psoriatic erythroderma: results from a 52⁃week, open⁃label study[J]. Br J Dermatol, 2017,176(3):741⁃751. doi: 10.1111/bjd. 14702. |
[39] | Pescitelli L, Dini V, Gisondi P, et al. Erythrodermic psoriasis treated with ustekinumab: an Italian multicenter retrospective analysis[J]. J Dermatol Sci, 2015,78(2):149⁃151. doi: 10.1016/j.jdermsci.2015.01.005. |
[40] | Buggiani G, D′Erme AM, Krysenka A, et al. Efficacy of ustekinumab in sub⁃erythrodermic psoriasis: when TNF⁃blockers fail[J]. Dermatol Ther, 2012,25(3):283⁃285. doi: 10.1111/j.1529⁃8019.2012.01465.x. |
[41] | Signa S, Campione E, Rusmini M, et al. Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumab[J]. Pediatr Rheumatol Online J, 2019,17(1):38. doi: 10.1186/s12969⁃019⁃0336⁃3. |
[42] | Sano S, Kubo H, Morishima H, et al. Guselkumab, a human interleukin⁃23 monoclonal antibody in Japanese patients with generalized pustular psoriasis and erythrodermic psoriasis: efficacy and safety analyses of a 52⁃week, phase 3, multicenter, open⁃label study[J]. J Dermatol, 2018,45(5):529⁃539. doi: 10.1111/1346⁃8138.14294. |
[43] | Trevisan G, Germi L, Naldi L. Erythrodermic psoriasis improved by Tildrakizumab[J]. Dermatol Reports, 2022,14(4):9448. doi: 10.4081/dr.2022.9448. |
[44] | Yamanaka K, Okubo Y, Yasuda I, et al. Efficacy and safety of risankizumab in Japanese patients with generalized pustular psoriasis or erythrodermic psoriasis: Primary analysis and 180⁃week follow⁃up results from the phase 3, multicenter IMMspire study[J]. J Dermatol, 2023,50(2):195⁃202. doi: 10.1111/1346⁃8138.16667. |
[45] | Gioe OA, Savoie C, Grieshaber EB, et al. Treatment of erythrodermic psoriasis with apremilast[J]. JAAD Case Rep, 2021,11:36⁃37. doi: 10.1016/j.jdcr.2021.03.011. |
[46] | Megna M, Ocampo⁃Garza SS, Fabbrocini G, et al. A case of erythrodermic psoriasis successfully treated with apremilast[J]. Dermatol Ther, 2022,35(1):e15204. doi: 10.1111/dth.15204. |
[47] | Imafuku S, Okubo Y, Tada Y, et al. Deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in Japanese patients with moderate to severe plaque, erythrodermic, or generalized pustular psoriasis: efficacy and safety results from the open⁃label, phase 3 POETYK PSO⁃4 trial[C]//European Academy of Dermatology and Venereology (EADV) 31st Congress, Milan, 2022. |
[48] | Hoy SM. Deucravacitinib: first approval[J]. Drugs, 2022,82(17):1671⁃1679. doi: 10.1007/s40265⁃022⁃01796⁃y. |
[49] | Sator P. Safety and tolerability of adalimumab for the treatment of psoriasis: a review summarizing 15 years of real⁃life experience[J]. Ther Adv Chronic Dis, 2018,9(8):147⁃158. doi: 10.1177/2040622318772705. |
[50] | Kurizky PS, Ferreira Cde C, Nogueira LS, et al. Treatment of psoriasis and psoriatic arthritis during pregnancy and breastfeeding[J]. An Bras Dermatol, 2015,90(3):367⁃375. doi: 10.1590/abd1806⁃4841.20153113. |
[51] | Förger F, Zbinden A, Villiger PM. Certolizumab treatment during late pregnancy in patients with rheumatic diseases: low drug levels in cord blood but possible risk for maternal infections. A case series of 13 patients[J]. Joint Bone Spine, 2016,83(3):341⁃343. doi: 10.1016/j.jbspin.2015.07.004. |
[52] | Eworuke E, Panucci G, Goulding M, et al. Use of tumor necrosis factor⁃alpha inhibitors during pregnancy among women who delivered live born infants[J]. Pharmacoepidemiol Drug Saf, 2019,28(3):296⁃304. doi: 10.1002/pds.4695. |
[53] | Owczarek W, Walecka I, Lesiak A, et al. The use of biological drugs in psoriasis patients prior to pregnancy, during pregnancy and lactation: a review of current clinical guidelines[J]. Postepy Dermatol Alergol, 2020,37(6):821⁃830. doi: 10.5114/ada.2020. 102089. |
[54] | Fujita H, Terui T, Hayama K, et al. Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of GPP[J]. J Dermatol, 2018,45(11):1235⁃1270. doi: 10.1111/1346⁃8138.14523. |
[55] | Shao S, Wang G, Maverakis E, et al. Targeted treatment for erythrodermic psoriasis: rationale and recent advances[J]. Drugs, 2020,80(6):525⁃534. doi: 10.1007/s40265⁃020⁃01283⁃2. |
[1] | Qi-Quan CHEN Song Zhi-Qiang WANG Gang. Guidelines for the diagnosis and treatment of refractory chronic spontaneous urticaria in China (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(6): 485-496. |
[2] | Yu Jinlei, Wu Qiaofang, Sun Yuexin, Bao Jun, Zhou Ying. Clinical experience with spesolimab therapy in six cases of generalized pustular psoriasis [J]. Chinese Journal of Dermatology, 2025, 0(5): 20240440-e20240440. |
[3] | Huang Hejin, Li Xinya, He Ziqing, Xi Wenwen, Tang Yujun, Zhang Jianfei, Xiao Xia, Jiang Bin, Yang Feng. Postoperative complications in 3 000 patients with axillary osmidrosis after minimally invasive rotary cutting surgery: a retrospective study [J]. Chinese Journal of Dermatology, 2025, 0(5): 20230291-e0230291. |
[4] | Committee on Psoriasis, Chinese Society of Dermatology. Expert proposal on apremilast for the treatment of psoriasis (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(5): 416-424. |
[5] | The Consensus Development Expert Group on Diagnosis and Treatment of Port-wine Stain in Chinese Children, Pediatric Dermatologist Committee, China Dermatologist Association. Expert consensus on diagnosis and treatment of port-wine stain in children (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(5): 396-404. |
[6] | China Dermatologist Association, Treatment Group, Chinese Society of Dermatology, Dermatology Branch of China International Exchange and Promotive Association for Medical and Health Care, National Clinical Research Center for Dermatologic and Immunologic Diseases, Rare Skin Diseases Committee, China Alliance for Rare Diseases. Diagnosis and treatment of bullous pemphigoid: an expert consensus statement (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(5): 405-415. |
[7] | Skin Cancer Research Group, Committee on Dermatology, Chinese Association of Integrative Medicine, Melanoma Society of China Anti-Cancer Association, Society of Integrated Rehabilitation of Skin Tumors, China Anti-Cancer Association. Expert consensus on diagnosis and treatment of pigmented nevi (2025 edition) [J]. Chinese Journal of Dermatology, 2025, 58(5): 387-395. |
[8] | Group on Children, Chinese Society of Dermatology, Dermatology and Venereology Group, Chinese Pediatric Society, Chinese Medical Association, Chinese Association of Rehabilitation Dermatology, Pediatric Dermatology Group, China Dermatologist Association. Expert consensus on the construction of specialized outpatient clinics and standardized case management of children with atopic dermatitis in China (2025 version) [J]. Chinese Journal of Dermatology, 2025, 0(4): 20240338-e20240338. |
[9] | Li Ziyu, Lu Yan. Paying attention to severe skin diseases after COVID-19 [J]. Chinese Journal of Dermatology, 2025, 58(4): 378-383. |
[10] | Bao Shijie, Han Mei, Zhou Xiaoyong. Analysis of factors influencing the efficacy of etanercept in the treatment of toxic epidermal necrolysis based on literature review [J]. Chinese Journal of Dermatology, 2025, 58(4): 352-355. |
[11] | Group on Pediatric Dermatology, China Dermatologist Association, Committee on Psoriasis, Chinese Society of Dermatology. Expert consensus on the diagnosis and treatment of pediatric pustular psoriasis in China (2025 version) [J]. Chinese Journal of Dermatology, 2025, 58(4): 297-306. |
[12] | He Chunxia, Jin Hongzhong . Principles, current status, challenges and perspectives in the diagnosis and treatment of critical dermatological emergencies [J]. Chinese Journal of Dermatology, 2025, 58(4): 307-314. |
[13] | Mu Kui, Guo Hui, Wen Haiquan, Long Hai, Liu Yu, Luo Shuaihantian, Huang Xin, Zhou Xingyu, Xiao Rong, Li Yaping. Efficacy and safety analysis of combined telitacicept in 25 patients with systemic lupus erythematosus based on standard therapy [J]. Chinese Journal of Dermatology, 2025, 58(4): 322-327. |
[14] | Chinese Society of Dermatology, China Dermatologist Association, Dermatology Branch of China International Exchange and Promotive Association for Medical and Health Care, Rare Skin Diseases Committee, China Alliance for Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases. Expert consensus on the diagnosis and treatment of paraneoplastic pemphigus in China (2025 version) [J]. Chinese Journal of Dermatology, 2025, 58(4): 289-296. |
[15] | Acne Study Group of China Dermatologist Association, Dermatology Professional Committee of Chinese Research Hospital Association, Acne Study Group of Dermatology and Venereology Professional Committee of Chinese Association of Integrative Medicine. Chinese expert consensus on clinical severity grading and therapeutic evaluation of acne vulgaris [J]. Chinese Journal of Dermatology, 2025, 0(4): 20250034-e20250034. |
|