Chinese Journal of Dermatology ›› 2020, Vol. 53 ›› Issue (2): 147-151.doi: 10.35541/cjd.20190093

• Reviews • Previous Articles     Next Articles

Psoriasis comorbidities

Chen Wenjuan1, Peng Chen1, Ding Yangfeng1, Shi Yuling2   

  1. 1Institute of Psoriasis, Tongji University School of Medicine, Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai 200443, China; 2Institute of Psoriasis, Tongji University School of medicine, Department of Dermatology and Venereology, Tenth People′s Hospital of Tongji University, Shanghai 200072, China
  • Received:2018-12-07 Revised:2019-06-16 Online:2020-02-15 Published:2020-02-01
  • Contact: Shi Yuling E-mail:shiyuling1973@tongji.edu.cn
  • Supported by:
    National Natural Science Foundation of China (81872522, 81673050); Shanghai Science and Technology Commission "Science and Technology Innovation Action Plan" (18140901800); Scientific Research Innovation Project of Shanghai Municipal Education Commission (2019-01-07-00-07-E00046); Excellent Talents Training Project in Shanghai Health System (2018BR30); Clinical Science and Technology Innovation Project of Shanghai Shen-kang Hospital Development Center (SHDC12018X06)

Abstract: 【Abstract】 Psoriasis is an immune-mediated chronic inflammatory disease, whose occurrence is closely associated with genes, immunity, environment and other factors. Classic comorbidities associated with psoriasis mainly include cardiovascular diseases, obesity and inflammatory bowel diseases. Emerging data have shown some other diseases closely associated with psoriasis, including metabolic syndrome, chronic renal diseases, tumors, infections, and so on. This review summarizes psoriasis-associated comorbidities that have been reported in studies, and analyzes the possible co-pathogenesis of these diseases and psoriasis.

Key words: Psoriasis, Comorbidity, Cardiovascular diseases, Diabetes mellitus, Obesity, Metabolic diseases, Autoimmune diseases