Chinese Journal of Dermatology ›› 2026, e20230524.doi: 10.35541/cjd.20230524

• Reviews • Previous Articles     Next Articles

Advances in the diagnosis and treatment of hypereosinophilic syndrome

Li Xiaorong, Wang Wenjuan, Li Chengxin   

  1. Department of Dermatology, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
  • Received:2023-09-11 Revised:2024-11-04 Online:2026-02-09 Published:2026-06-22
  • Contact: Li Chengxin E-mail:chengxinderm@163.com

Abstract: 【Abstract】 Hypereosinophilic syndrome (HES) represents a heterogeneous group of disorders. In 2012, the International Cooperative Working Group on Eosinophil Disorders, composed of multidisciplinary experts, updated the diagnostic criteria for HES, which have since been widely accepted. Over the past decade, based on new discoveries about disease pathogenesis, biomarkers, and therapeutic targets, further updates to the diagnosis and classification of HES have been proposed. This review summarizes the latest advances in the diagnostic criteria, classification, and treatment of HES, with the aim of standardizing the diagnosis, treatment, and management of HES and assisting clinicians in selecting effective therapeutic strategies in an accurate and timely manner.

Key words: Eosinophils, Hypereosinophilic syndrome, Diagnosis, Therapy, Classification