Chinese Journal of Dermatology ›› 2025, Vol. 58 ›› Issue (12): 1121-1129.doi: 10.35541/cjd.20250045

• Guidelines and Consensus • Previous Articles     Next Articles

Expert consensus on diagnosis and treatment of pyoderma gangrenosum (2025 edition)

Chinese Society of Dermatology; China Dermatologist Association   

  1. Chinese Society of Dermatology; China Dermatologist Association
  • Received:2025-01-24 Revised:2025-06-17 Online:2025-12-15 Published:2025-12-04
  • Contact: Geng Songmei; Wang Gang E-mail:gengsongmei73@163.com; xjwgang@ fmmu.edu.cn

Abstract: 【Abstract】 Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis. Its most common clinical manifestation is the occult development of ulcers in normal or traumatized skin. PG is often associated with other systemic diseases. Early diagnosis and standardized treatment are crucial for managing PG and its associated comorbidities. Currently, there are no relevant diagnostic and therapeutic guidelines or consensus in China. Based on the latest Chinese and international research progress and international guidelines, the Chinese Society of Dermatology and the China Dermatologist Association organized experts in the relevant fields to develop this consensus using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach and the Delphi method. This consensus focuses on the diagnostic criteria, severity assessment, and treatment strategies for PG, with the aim of providing guidance on the diagnosis, treatment, and long-term management of PG in China.

Key words: Pyoderma gangrenosum, Diagnosis, Therapy, Disease management, Expert consensus