Chinese Journal of Dermatology ›› 2025, e0250045.doi: 10.35541/cjd.20250045

• Guidelines and Consensus • Previous Articles    

Expert consensus on diagnosis and treatment of pyoderma gangrenosum (2025 edition)

Chinese Society of Dermatology; Chinese Dermatologist Association   

  1. Chinese Society of Dermatology; Chinese Dermatologist Association
  • Received:2025-01-24 Revised:2025-06-17 Online:2025-03-12 Published:2025-09-24
  • Contact: Geng Songmei; Wang Gang E-mail:gengsongmei73@163.com; xjwgang@fmmu.edu.cn

Abstract: 【Abstract】 Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis. Its most common clinical manifestation is the occult development of ulcers in normal or traumatized skin. PG is often associated with other systemic diseases. Early diagnosis and standardized treatment are crucial for managing PG and associated comorbidities. Currently, there are no specific diagnostic and therapeutic guidelines or consensus in China. The Chinese Society of Dermatology and the Chinese Dermatologist Association organized experts in the relevant fields to reach a consensus on the diagnostic criteria, severity assessment, and treatment strategies for PG. This consensus, developed through the Delphi method and based on the latest domestic and international research progress and international guidelines, applies the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to guide the diagnosis, treatment, and long?term management of PG in China.

Key words: Pyoderma gangrenosum, Diagnosis, Therapy, Disease management, Expert consensus