Chinese Journal of Dermatology ›› 2022, Vol. 55 ›› Issue (6): 465-470.doi: 10.35541/cjd.20210885

• Guidelines and Consensus • Previous Articles     Next Articles

Treatment of atopic dermatitis with dupilumab: an expert consensus

Working Group for Atopic Dermatitis, Chinese Society of Dermatology; Working Group for Children′s Diseases, Chinese Society of Dermatology   

  1. Working Group for Atopic Dermatitis, Chinese Society of Dermatology; Working Group for Children′s Diseases, Chinese Society of Dermatology
  • Received:2021-12-06 Revised:2022-05-10 Online:2022-06-15 Published:2022-06-02
  • Contact: Zhang Jianzhong; Ma Lin E-mail:rmzjz@126.com; bch_maleen@aliyun.com

Abstract: 【Abstract】 Atopic dermatitis is a chronic inflammatory skin disease, characterized by eczematous dermatitis and severe pruritus, and has severe impact on patients′ quality of life. Patients with moderate to severe atopic dermatitis often require systemic treatments, but traditional systemic treatments are ineffective or intolerable in some patients. In recent years, several biological agents have been applied to the treatment of atopic dermatitis in clinical practice, among which the interleukin-4 receptor antagonist dupilumab has been marketed in China. Some experts in related fields from Working Group for Atopic Dermatitis, Chinese Society of Dermatology and Working Group for Children′s Diseases, Chinese Society of Dermatology discussed the application of dupilumab in the treatment of moderate to severe atopic dermatitis, and developed a consensus, in the hope of providing a reference for the clinical application of dupilumab in the treatment of atopic dermatitis.

Key words: Dermatitis, atopic, Therapy, Biological agents, Receptors, interleukin-4, Type 2 inflammation, Dupilumab