Chinese Journal of Dermatology ›› 2019, Vol. 52 ›› Issue (3): 208-210.doi: 10.3760/cma.j.issn.0412-4030.2019.03.014

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Pathogenesis of androgenetic alopecia

Tang Shunli, Fang Hong   

  1. Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
  • Received:2018-03-12 Revised:2018-12-31 Online:2019-03-15 Published:2019-03-04
  • Contact: Fang Hong E-mail:fanghongzy@sina.com
  • Supported by:
    National Natural Science Foundation of China (81673045)

Abstract: 【Abstract】 Androgenetic alopecia (AGA) is the most common type of non-cicatricial alopecia. Many researches have indicated that the pathogenesis of AGA involves genetic background, abnormal metabolism of sex hormones and follicle miniaturization, hair follicle microinflammation and environmental factors. Among them, genetic susceptibility is the most important factor for the individual difference of AGA, and follicle miniaturization induced by abnormal sex hormone metabolism and/or hair follicle microinflammation is the last step in the occurrence of AGA.

Key words: Alopecia, Skin diseases, genetic, Androgens, Androgenetic alopecia, Microinflammation

CLC Number: 

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