Chinese Journal of Dermatology ›› 2023, e20210949.doi: 10.35541/cjd.20210949

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Ultraviolet and androgenetic alopecia

Shen Yuqing, Song Xiuzu   

  1. Department of Dermatology, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou Third People′s Hospital, Hangzhou 310009, China
  • Received:2021-12-30 Revised:2022-05-11 Online:2023-01-05 Published:2023-03-20
  • Contact: Song Xiuzu
  • Supported by:
    National Natural Science Foundation of China(81872517)

Abstract: Ultraviolet exposure may promote the development of androgenetic alopecia. On the one hand, ultraviolet irradiation can cause perifollicular inflammation through oxidative stress and microecological changes, and can also induce keratinocytes, melanocytes and mast cells to participate in the development of follicular microinflammation; on the other hand, ultraviolet irradiation can cause the aging of hair follicle stem cells, dermal papilla cells and dermal fibroblasts, as well as the increase of elastic fibers. This review summarizes relevant literature in recent years, in order to provide a theoretical basis for advocating protection of the hair and scalp against sunlight to prevent androgenetic alopecia.

Key words: Ultraviolet rays, Alopecia, Inflammation, Cell aging, Androgenetic alopecia