Chinese Journal of Dermatology ›› 2022, Vol. 55 ›› Issue (7): 641-644.doi: 10.35541/cjd.20210253

• Reviews • Previous Articles    

Cell mechanics in dermatology

Feng Hua1, Gao Yingshu1, Li Qing1, Sun Lianwen2#br#


  1. 1Department of Dermatology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China; 2Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China

  • Received:2021-03-26 Revised:2021-10-14 Online:2022-07-15 Published:2022-07-05
  • Contact: Sun Lianwen

Abstract: 【Abstract】 Cell mechanics is a new interdiscipline, which focuses on the relationship between cell mechanical properties and cell behaviors, as well as physiological processes in tissues, organs and the body. Through the perception of and response to mechanical signals, cells participate in physiological activities of skin, bones, eyes and other organs, and the occurrence and development of diseases, including the regeneration, reconstruction and adaptive changes of skin tissues and the pathogenesis of various skin diseases. Cell mechanics has become a hot spot in the research of skin diseases in recent years. This review summarizes recent progress in cell mechanics-associated basic research, as well as in its research and application in scars, bedsores, vitiligo, skin tumors, hair diseases, etc., aiming to provide possible methods and strategies for the treatment of skin diseases.

Key words: Dermatology, Cicatrix, Skin neoplasms, Alopecia, Cell mechanics