Chinese Journal of Dermatology ›› 2022, Vol. 55 ›› Issue (12): 1118-1121.doi: 10.35541/cjd.20200563

• Reviews • Previous Articles     Next Articles

Small-molecule targeted drugs and biological agents for alopecia areata

Ding Yuwei, Qiao Jianjun, Fang Hong   

  1. Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
  • Received:2020-06-08 Revised:2020-10-26 Online:2022-12-15 Published:2022-12-05
  • Contact: Fang Hong
  • Supported by:
    National Natural Science Foundation of China(81972931)

Abstract: 【Abstract】 Traditional therapies for alopecia areata, especially moderate to severe alopecia areata and special types of alopecia areata, remain unsatisfactory. Compared with traditional therapies, small-molecule targeted drugs and biological agents have advantages of more rapid and marked efficacy, however, some patients may experience adverse reactions such as infections during treatment or relapses after drug withdrawal. Thus, their efficacy and safety still need to be further evaluated. This review summarizes research progress in small-molecule targeted drugs and biological agents in the treatment of alopecia areata.

Key words: Alopecia areata, Molecular targeted therapy, Biological therapy