Abstract: 【Abstract】 Livedoid vasculopathy is a rare chronic ischemic necrotic skin disease caused by microvascular thrombosis in superficial vascular plexuses. Effective treatments are lacking. Efficacy of anticoagulants has been clinically proven in the treatment of this disease, but the administration route and adverse reactions limit their extensive application. The new oral factor Xa inhibitor rivaroxaban, which has many advantages, such as no need for coagulation monitoring, few adverse reactions and convenient oral administration, can be used in the prevention and treatment of thrombosis and post-thrombotic ulcers, and it . In this article, 3 patients with livedoid vasculopathy were treated with rivaroxaban alone or in combination, and satisfactory efficacy was obtained.

Key words: Skin diseases, vascular, Anticoagulants, Treatment outcome, Livedoid vasculopathy, Rivaroxaban