中华皮肤科杂志 ›› 2026, Vol. 59 ›› Issue (5): 396-406.doi: 10.35541/cjd.20250597
中国妇幼保健协会儿童变态反应专业委员会儿童皮肤病学组
收稿日期:2025-10-28
修回日期:2026-03-11
发布日期:2026-04-30
通讯作者:
李钦峰;高莹;徐子刚
E-mail:lyz20061217@sina.com
Pediatric Dermatology Group, Professional Committee of Pediatric Allergy, China Maternal and Child Health Association
Received:2025-10-28
Revised:2026-03-11
Published:2026-04-30
Contact:
Li Qinfeng; Gao Ying; Xu Zigang
E-mail:lyz20061217@sina.com
摘要: 【摘要】 儿童肛门生殖器硬化性苔藓是一种发生于生殖器肛门部位的慢性炎症性疾病,病情严重者可造成解剖结构改变,出现排尿及排便困难,严重影响患儿身心健康及生活质量。中国妇幼保健协会儿童变态反应专业委员会儿童皮肤病学组组织我国儿童皮肤科及泌尿外科专家,在综合国内外临床研究的基础上,依据循证医学证据及专家意见,从临床表现、诊断及鉴别诊断、疾病评估、治疗方案选择及随访等方面进行了全面梳理,形成了专家共识,为临床医师诊疗提供指导。
中国妇幼保健协会儿童变态反应专业委员会儿童皮肤病学组. 儿童肛门生殖器硬化性苔藓诊疗管理中国专家共识(2026版)[J]. 中华皮肤科杂志, 2026,59(5):396-406. doi:10.35541/cjd.20250597
Pediatric Dermatology Group, Professional Committee of Pediatric Allergy, China Maternal and Child Health Association. Chinese expert consensus on the diagnosis and management of pediatric anogenital lichen sclerosus (2026 edition)[J]. Chinese Journal of Dermatology, 2026, 59(5): 396-406.doi:10.35541/cjd.20250597
| [1] | Simms⁃Cendan J, Hoover K, Marathe K, et al. NASPAG clinical opinion: diagnosis and management of lichen sclerosis in pediatric and adolescent patients[J]. J Pediatr Adolesc Gynecol, 2022,35(2):112⁃120. DOI: 10.1016/j.jpag.2021.09.008. |
| [2] | Lewis FM, Tatnall FM, Velangi SS, et al. British Association of Dermatologists guidelines for the management of lichen sclerosus, 2018[J]. Br J Dermatol, 2018,178(4):839⁃853. DOI: 10.1111/bjd.16241. |
| [3] | Morrel B, van Eersel R, Burger CW, et al. The long⁃term clinical consequences of juvenile vulvar lichen sclerosus: a systematic review[J]. J Am Acad Dermatol, 2020,82(2):469⁃477. DOI: 10.1016/j.jaad.2019.08.030. |
| [4] | Nerantzoulis I, Grigoriadis T, Michala L. Genital lichen sclerosus in childhood and adolescence⁃a retrospective case series of 15 patients: early diagnosis is crucial to avoid long⁃term sequelae[J]. Eur J Pediatr, 2017,176(10):1429⁃1432. DOI: 10. 1007/s00431⁃017⁃3004⁃y. |
| [5] | Crofts VL, Moussaoui D, Shynkarova V, et al. Paediatric and adolescent vulvar lichen sclerosus: delay in diagnosis[J]. Eur J Pediatr, 2025,184(3):232. DOI: 10.1007/s00431⁃025⁃06063⁃2. |
| [6] | Kirtschig G, Kinberger M, Kreuter A, et al. EuroGuiderm guideline on lichen sclerosus⁃introduction into lichen sclerosus[J]. J Eur Acad Dermatol Venereol, 2024,38(10):1850⁃1873. DOI: 10.1111/jdv.20082. |
| [7] | OCEBM Levels of Evidence Working Group. The Oxford 2011 Levels of Evidence. Oxford Centre for Evidence⁃Based Medicine [EB/OL]. [2025⁃06⁃29]. https://www.cebm.ox.ac.uk/resources/levels⁃of⁃evidence/ocebm⁃levels⁃of⁃evidence. |
| [8] | Hohmann E, Brand JC, Rossi MJ, et al. Expert opinion is necessary: Delphi panel methodology facilitates a scientific approach to consensus[J]. Arthroscopy, 2018,34(2):349⁃351. DOI: 10.1016/j.arthro.2017.11.022. |
| [9] | Kumar KS, Morrel B, van Hees C, et al. Comparison of lichen sclerosus in boys and girls: a systematic literature review of epidemiology, symptoms, genetic background, risk factors, treatment, and prognosis[J]. Pediatr Dermatol, 2022,39(3):400⁃408. DOI: 10.1111/pde.14967. |
| [10] | Orszulak D, Dulska A, Niziński K, et al. Pediatric vulvar lichen sclerosus⁃a review of the literature[J]. Int J Environ Res Public Health, 2021,18(13):7153. DOI: 10.3390/ijerph18137153. |
| [11] | Promm M, Rösch WH, Kirtschig G. Lichen sclerosus in children[J]. Urologe A, 2020,59(3):271⁃277. DOI: 10.1007/s00120⁃020⁃01140⁃w. |
| [12] | Balakirski G, Grothaus J, Altengarten J, et al. Paediatric lichen sclerosus: a systematic review of 4516 cases[J]. Br J Dermatol, 2020,182(1):231⁃233. DOI: 10.1111/bjd.18267. |
| [13] | Gargollo PC, Kozakewich HP, Bauer SB, et al. Balanitis xerotica obliterans in boys[J]. J Urol, 2005,174(4 Pt 1):1409⁃1412. DOI: 10.1097/01.ju.0000173126.63094.b3. |
| [14] | Pradhan A, Patel R, Said AJ, et al. 10 years' experience in balanitis xerotica obliterans: a single⁃institution study[J]. Eur J Pediatr Surg, 2019,29(3):302⁃306. DOI: 10.1055/s⁃0038⁃1668562. |
| [15] | Nguyen A, Holland A. Balanitis xerotica obliterans: an update for clinicians[J]. Eur J Pediatr, 2020,179(1):9⁃16. DOI: 10. 1007/s00431⁃019⁃03516⁃3. |
| [16] | Powell J, Wojnarowska F. Childhood vulvar lichen sclerosus: an increasingly common problem[J]. J Am Acad Dermatol, 2001,44(5):803⁃806. DOI: 10.1067/mjd.2001.113474. |
| [17] | Dinh H, Purcell SM, Chung C, et al. Pediatric lichen sclerosus: a review of the literature and management recommendations[J]. J Clin Aesthet Dermatol, 2016,9(9):49⁃54. |
| [18] | Torres A, Zaborek⁃Łyczba M, Łyczba J, et al. The importance of immunological disorders in the pathogenesis of lichen sclerosus in pediatric patients: a systematic review[J]. Int J Mol Sci, 2022,23(22):14212. DOI: 10.3390/ijms232214212. |
| [19] | Terlou A, Santegoets LA, van der Meijden WI, et al. An autoimmune phenotype in vulvar lichen sclerosus and lichen planus: a Th1 response and high levels of microRNA⁃155[J]. J Invest Dermatol, 2012,132(3 Pt 1):658⁃666. DOI: 10.1038/jid. 2011.369. |
| [20] | Powell J, Wojnarowska F, Winsey S, et al. Lichen sclerosus premenarche: autoimmunity and immunogenetics[J]. Br J Dermatol, 2000,142(3):481⁃484. DOI: 10.1046/j.1365⁃2133. 2000.03360.x. |
| [21] | Aslanian FM, Marques MT, Matos HJ, et al. HLA markers in familial lichen sclerosus[J]. J Dtsch Dermatol Ges, 2006,4(10):842⁃847. DOI: 10.1111/j.1610⁃0387.2006.06087.x. |
| [22] | Sherman V, McPherson T, Baldo M, et al. The high rate of familial lichen sclerosus suggests a genetic contribution: an observational cohort study[J]. J Eur Acad Dermatol Venereol, 2010,24(9):1031⁃1034. DOI: 10.1111/j.1468⁃3083.2010.03572.x. |
| [23] | Higgins CA, Cruickshank ME. A population⁃based case⁃control study of aetiological factors associated with vulval lichen sclerosus[J]. J Obstet Gynaecol, 2012,32(3):271⁃275. DOI: 10.3109/01443615.2011.649320. |
| [24] | Virgili A, Borghi A, Cazzaniga S, et al. New insights into potential risk factors and associations in genital lichen sclerosus: data from a multicentre Italian study on 729 consecutive cases[J]. J Eur Acad Dermatol Venereol, 2017,31(4):699⁃704. DOI: 10.1111/jdv.13867. |
| [25] | Sander CS, Ali I, Dean D, et al. Oxidative stress is implicated in the pathogenesis of lichen sclerosus[J]. Br J Dermatol, 2004,151(3):627⁃635. DOI: 10.1111/j.1365⁃2133.2004.06142.x. |
| [26] | Owen CM, Yell JA. Genital lichen sclerosus associated with incontinence[J]. J Obstet Gynaecol, 2002,22(2):209⁃210. DOI: 10.1080/01443610120113454. |
| [27] | Edmonds EV, Bunker CB. Nuclear magnetic resonance spectroscopy of urine in male genital lichen sclerosus[J]. Br J Dermatol, 2010,163(6):1355⁃1356. DOI: 10.1111/j.1365⁃2133. 2010.09980.x. |
| [28] | Edwards SK, Bunker CB, van der Snoek EM, et al. 2022 European guideline for the management of balanoposthitis[J]. J Eur Acad Dermatol Venereol, 2023,37(6):1104⁃1117. DOI: 10. 1111/jdv.18954. |
| [29] | Kravvas G, Muneer A, Watchorn RE, et al. Male genital lichen sclerosus, microincontinence and occlusion: mapping the disease across the prepuce[J]. Clin Exp Dermatol, 2022,47(6):1124⁃1130. DOI: 10.1111/ced.15127. |
| [30] | Panou E, Panagou E, Foley C, et al. Male genital lichen sclerosus associated with urological interventions and microincontinence: a case series of 21 patients[J]. Clin Exp Dermatol, 2022,47(1):107⁃109. DOI: 10.1111/ced.14869. |
| [31] | Villa M, Dragonetti E, Grande M, et al. Skin phototype and local trauma in the onset of balanitis xerotica obliterans (BXO) in circumcised patients[J]. In Vivo, 2012,26(1):143⁃146. |
| [32] | Bjekić M, Šipetić S, Marinković J. Risk factors for genital lichen sclerosus in men[J]. Br J Dermatol, 2011,164(2):325⁃329. DOI: 10.1111/j.1365⁃2133.2010.10091.x. |
| [33] | Winfrey OK, Fei YF, Dendrinos ML, et al. Lichen sclerosus throughout childhood and adolescence: not only a premenarchal disease[J]. J Pediatr Adolesc Gynecol, 2022,35(6):624⁃628. DOI: 10.1016/j.jpag.2022.08.011. |
| [34] | 李艳, 张莉, 谢玉燕, 等. 儿童外阴硬化性苔藓79例皮肤镜特征分析[J]. 中华皮肤科杂志, 2022,55(10):885⁃888. DOI: 10. 35541/cjd.20210447. |
| [35] | Liu J, Hao J, Liu Y, et al. Dermoscopic features of lichen sclerosus in Asian patients: a prospective study[J]. J Eur Acad Dermatol Venereol, 2020,34(11):e720⁃e721. DOI: 10.1111/jdv. 16540. |
| [36] | Han Y, Liu R, Li Y. Dermatoscopic features of vulvar lichen sclerosus in children: a retrospective study[J]. Pediatr Dermatol, 2024,41(6):1091⁃1095. DOI: 10.1111/pde.15743. |
| [37] | Chen L, Wang Y, Qin B, et al. Reflectance confocal microscopy features of vulvar lichen sclerosus in Chinese juvenile girls[J]. J Dermatol, 2023,50(11):1497⁃1500. DOI: 10.1111/1346⁃8138. 16884. |
| [38] | Chen L, Wang Y, Gao X, et al. In vivo evaluation of vulvar lichen sclerosus with reflectance confocal microscopy and therapeutic monitoring in children[J]. Skin Res Technol, 2023,29(1):e13234. DOI: 10.1111/srt.13234. |
| [39] | Chen L, Wang Y, Wang J, et al. Male genital lichen sclerosus in a pediatric case: a focus on the reflectance confocal microscopy presentation[J]. Skin Res Technol, 2023,29(3):e13304. DOI: 10.1111/srt.13304. |
| [40] | Wang Y, Chen L, Qin B, et al. Reflectance confocal microscopy as a complementary diagnostic tool for vulvar lichen sclerosus and vulvar vitiligo in juvenile Chinese girls[J]. Exp Dermatol, 2024,33(3):e15033. DOI: 10.1111/exd.15033. |
| [41] | 万立, 陈金波, 姜倩, 等. 反射式共聚焦显微镜在界面皮炎中的应用研究进展[J]. 中华皮肤科杂志, 2023,56(10):982⁃985. DOI: 10.35541/cjd.20210269. |
| [42] | 张莉, 浦芸静, 江弘婧, 等. 女童会阴部硬化性苔藓21例皮肤影像学特征及临床与病理分析[J]. 临床皮肤科杂志, 2023,52(5):270⁃275. DOI: 10.16761/j.cnki.1000⁃4963.2023.05.005. |
| [43] | Yalici⁃Armagan B, Bostan E, Akdogan N, et al. Paediatric lichen sclerosus et atrophicus: a retrospective analysis of 38 paediatric patients[J]. Int J Clin Pract, 2021,75(10):e14661. DOI: 10. 1111/ijcp.14661. |
| [44] | Becker K, Meissner V, Farwick W, et al. Lichen sclerosus and atopy in boys: coincidence or correlation?[J]. Br J Dermatol, 2013,168(2):362⁃366. DOI: 10.1111/j.1365⁃2133.2012.11201.x. |
| [45] | Erni B, Navarini AA, Huang D, et al. Proposition of a severity scale for lichen sclerosus: the "Clinical Lichen Sclerosus Score"[J]. Dermatol Ther, 2021,34(2):e14773. DOI: 10.1111/dth. 14773. |
| [46] | 赵兴, 邓常开, 彭强, 等. 最大尿流率变化在男童生殖器硬化性苔藓样变治疗中的临床意义[J]. 临床小儿外科杂志, 2025,24(1):39⁃44. DOI: 10.3760/cma.j.cn101785⁃202207032⁃008. |
| [47] | Meuli M, Briner J, Hanimann B, et al. Lichen sclerosus et atrophicus causing phimosis in boys: a prospective study with 5⁃year followup after complete circumcision[J]. J Urol, 1994,152(3):987⁃989. DOI: 10.1016/s0022⁃5347(17)32638⁃1. |
| [48] | Kirtschig G, Kinberger M, Kreuter A, et al. EuroGuiderm guideline on lichen sclerosus⁃treatment of lichen sclerosus[J]. J Eur Acad Dermatol Venereol, 2024,38(10):1874⁃1909. DOI: 10.1111/jdv.20083. |
| [49] | Almadori A, Zenner N, Boyle D, et al. Development and validation of a clinical grading scale to assess the vulvar region: the vulvar architecture severity scale[J]. Aesthet Surg J, 2020,40(12):1319⁃1326. DOI: 10.1093/asj/sjz342. |
| [50] | Virgili A, Minghetti S, Borghi A, et al. Long⁃term maintenance therapy for vulvar lichen sclerosus: the results of a randomized study comparing topical vitamin E with an emollient[J]. Eur J Dermatol, 2013,23(2):189⁃194. DOI: 10.1684/ejd.2013.1987. |
| [51] | 高建宏, 杨雅琴, 高金荣, 等. 血管内皮生长因子和碱性成纤维细胞生长因子在外阴白色病变组织中的表达[J]. 中国妇产科临床杂志, 2011,12(1):42⁃44. DOI: 10.3969/j.issn.1672⁃1861.2011.01.013. |
| [52] | 赖慧敏, 邓新粮, 薛敏, 等. bFGF、FGFR⁃1在外阴鳞状上皮增生组织中表达及意义[J]. 实用预防医学, 2011,18(1):22⁃25. DOI: 10.3969/j.issn.1006⁃3110.2011.01.009. |
| [53] | 曲微, 何岩, 袁晓峰, 等. 重组牛碱性成纤维细胞生长因子联合红光治疗女性外阴硬化性苔藓疗效观察[J]. 人民军医, 2021,64(1):73⁃75. DOI: 10.3969/j.issn.1000⁃9736.2021.01. 022. |
| [54] | Virgili A, Corazza M, Minghetti S, et al. Growing evidence for topical mometasone fuoroate in the treatment of vulvar lichen sclerosus[J]. Maturitas, 2015,80(1):113⁃115. DOI: 10.1016/j.maturitas.2014.09.005. |
| [55] | Corazza M, Maietti E, Toni G, et al. Combining topical tretinoin with mometasone furoate in the treatment of vulvar lichen sclerosus: results of dermoscopic assessment[J]. Dermatol Ther, 2018,31(6):e12735. DOI: 10.1111/dth.12735. |
| [56] | Cattaneo A, De Magnis A, Botti E, et al. Topical mometasone furoate for vulvar lichen sclerosus[J]. J Reprod Med, 2003,48(6):444⁃448. |
| [57] | Liu L, He Y, Hu Q, et al. Vulvar lichen sclerosus in girls and adult females: a single⁃center retrospective study of 744 patients in China[J]. J Dermatol, 2024,51(11):1470⁃1475. DOI: 10. 1111/1346⁃8138.17352. |
| [58] | Akel R, Fuller C. Updates in lichen sclerosis: British Association of Dermatologists guidelines for the management of lichen sclerosus 2018[J]. Br J Dermatol, 2018,178(4):823⁃824. DOI: 10.1111/bjd.16445. |
| [59] | Virgili A, Borghi A, Toni G, et al. First randomized trial on clobetasol propionate and mometasone furoate in the treatment of vulvar lichen sclerosus: results of efficacy and tolerability[J]. Br J Dermatol, 2014,171(2):388⁃396. DOI: 10.1111/bjd.12910. |
| [60] | Mashayekhi S, Flohr C, Lewis FM. The treatment of vulval lichen sclerosus in prepubertal girls: a critically appraised topic[J]. Br J Dermatol, 2017,176(2):307⁃316. DOI: 10.1111/bjd. 15202. |
| [61] | Kirtschig G, Becker K, Günthert A, et al. Evidence⁃based (S3) guideline on (anogenital) lichen sclerosus[J]. J Eur Acad Dermatol Venereol, 2015,29(10):e1⁃e43. DOI: 10.1111/jdv. 13136. |
| [62] | Casey GA, Cooper SM, Powell JJ. Treatment of vulvar lichen sclerosus with topical corticosteroids in children: a study of 72 children[J]. Clin Exp Dermatol, 2015,40(3):289⁃292. DOI: 10. 1111/ced.12519. |
| [63] | Luesley DM, Downey GP. Topical tacrolimus in the management of lichen sclerosus[J]. BJOG, 2006, 113(7):832⁃834. DOI: 10. 1111/j.1471⁃0528.2006.00977.x. |
| [64] | Fistarol SK, Itin PH. Diagnosis and treatment of lichen sclerosus: an update[J]. Am J Clin Dermatol, 2013,14(1):27⁃47. DOI: 10.1007/s40257⁃012⁃0006⁃4. |
| [65] | Li Y, Xiao Y, Wang H, et al. Low⁃concentration topical tacrolimus for the treatment of anogenital lichen sclerosus in childhood: maintenance treatment to reduce recurrence[J]. J Pediatr Adolesc Gynecol, 2013,26(4):239⁃242. DOI: 10.1016/j.jpag.2012.11.010. |
| [66] | Hengge UR, Krause W, Hofmann H, et al. Multicentre, phaseⅡ trial on the safety and efficacy of topical tacrolimus ointment for the treatment of lichen sclerosus[J]. Br J Dermatol, 2006,155(5):1021⁃1028. DOI: 10.1111/j.1365⁃2133.2006.07446.x. |
| [67] | Zundell MP, Al⁃Dehneem R, Song T, et al. Novel clinical applications of topical ruxolitinib: a case series[J]. J Drugs Dermatol, 2024,23(3):188⁃190. DOI: 10.36849/jdd.7696. |
| [68] | Sharma S, Bandhade A, Singh MK, et al. The role of JAK inhibitors in pediatric lichen sclerosus et atrophicus: a case report[J]. Cureus, 2025,17(6):e85922. DOI: 10.7759/cureus. 85922. |
| [69] | Feng H, Zhu C, Jin H. The efficacy and safety of 5⁃aminolevulinic acid photodynamic therapy (ALA⁃PDT) as an adjunct therapy for symptoms in patients with dissecting cellulitis of the scalp: a retrospective study[J]. Photodiagnosis Photodyn Ther, 2021,34:102322. DOI: 10.1016/j.pdpdt.2021. 102322. |
| [70] | Zhang S, Wang Y, Wang J, et al. The efficacy of 5⁃aminolevulinic acid photodynamic therapy for pediatric vulvar lichen sclerosus[J]. Photodiagnosis Photodyn Ther, 2024,45:103986. DOI: 10.1016/j.pdpdt.2024.103986. |
| [71] | Bighetti S, Mancon S, Suardi N, et al. Evaluating lichen sclerosus in phimosis: insights from a multidisciplinary retrospective study[J]. Australas J Dermatol, 2025,66(2):e39⁃e42. DOI: 10.1111/ajd.14417. |
| [72] | Esperto F, Verla W, Ploumidis A, et al. What is the role of single⁃stage oral mucosa graft urethroplasty in the surgical management of lichen sclerosus⁃related stricture disease in men? A systematic review[J]. World J Urol, 2022,40(2):393⁃408. DOI: 10.1007/s00345⁃021⁃03803⁃5. |
| [73] | Doiron PR, Bunker CB. Obesity⁃related male genital lichen sclerosus[J]. J Eur Acad Dermatol Venereol, 2017,31(5):876⁃879. DOI: 10.1111/jdv.14035. |
| [74] | Homer L, Buchanan KJ, Nasr B, et al. Meatal stenosis in boys following circumcision for lichen sclerosus (balanitis xerotica obliterans)[J]. J Urol, 2014,192(6):1784⁃1788. DOI: 10.1016/j.juro.2014.06.077. |
| [75] | Faily S, Chhabra S, Corbett HJ. Meatal surgery at the time of circumcision for lichen sclerosus (LS/BXO) does not reduce the need for later meatal intervention: a retrospective cohort study[J]. J Pediatr Surg, 2024,59(9):1846⁃1850. DOI: 10.1016/j.jpedsurg.2024.05.010. |
| [76] | 孙彬, 马珂, 郎根强, 等. 口腔黏膜移植物尿道成形术治疗硬化性萎缩性苔藓样变相关尿道狭窄的远期疗效[J]. 海军医学杂志, 2025,46(8):857⁃858. DOI: 10.3969/j.issn.1009⁃0754. 2025.08.022. |
| [77] | Dendrinos ML, Quint EH. Lichen sclerosus in children and adolescents[J]. Curr Opin Obstet Gynecol, 2013,25(5):370⁃374. DOI: 10.1097/GCO.0b013e328363a53c. |
| [78] | Boero V, Cavalli R, Caia C, et al. Pediatric vulvar lichen sclerosus: does it resolve or does it persist after menarche?[J]. Pediatr Dermatol, 2023,40(3):472⁃475. DOI: 10.1111/pde. 15308. |
| [79] | Singh N, Mishra N, Ghatage P. Treatment options in vulvar lichen sclerosus: a scoping review[J]. Cureus, 2021,13(2):e13527. DOI: 10.7759/cureus.13527. |
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| [5] | 孙松朋 龙俊红 曹波 徐月 张相安 曹晖 谢钧 桂平 孙小君 张波 许志杰 李进安 王志刚 吴伟 杨会举 韦平 刘丛丛 沈庆波 俞凡 褚洪川 周阳洋 刘甲鑫 刘彦 霍兴霄 陈航 荆涛 高静 王艳逊 王锐 李振宇 张书信. 肤痔清软膏与曲安奈德益康唑乳膏治疗肛周慢性湿疹的临床疗效和安全性:一项多中心、随机、对照、双盲、等效性研究[J]. 中华皮肤科杂志, 2026, 0(5): 20250421-e20250421. |
| [6] | 中国“一带一路”皮肤病学专科联盟水疱病专病联盟 中华医学会皮肤性病学分会天疱疮/大疱性类天疱疮研究协作组. 抗p200类天疱疮诊断与治疗专家共识(2026版)[J]. 中华皮肤科杂志, 2026, 59(5): 387-395. |
| [7] | 崔若然, 宁小荔 杨俊刚 李承旭 常建民 陈玉迪. 反射式共聚焦显微镜联合皮肤镜对基底细胞癌的诊断价值评估[J]. 中华皮肤科杂志, 2026, 59(5): 436-442. |
| [8] | 中国医学装备协会皮肤病与皮肤美容分会 中国临床肿瘤学会患者教育专家委员会. [开放获取] 肿瘤治疗相关皮肤不良反应多学科管理中国专家共识(2026版)[J]. 中华皮肤科杂志, 2026, 59(4): 304-319. |
| [9] | 陈雪 张建中. [开放获取] 慢性手部湿疹:流行病学、疾病负担、发病机制及管理[J]. 中华皮肤科杂志, 2026, 59(4): 327-332. |
| [10] | 薛舒月 李婷婷 康晓静. 脂质代谢在皮肤恶性肿瘤发生发展及诊疗中的研究进展 [J]. 中华皮肤科杂志, 2026, 59(4): 379-382. |
| [11] | 王碧伟 李赛 乐文静 赵诗轩 陈雅丽 赵园园 甘璐 朱小凤 苏晓红. 磁微粒化学发光法检测梅毒特异性抗体的复检范围探讨研究[J]. 中华皮肤科杂志, 2026, 59(4): 370-373. |
| [12] | 黄祺甯 马银超 王子元 鲁锡霖 齐映婷 刘孜妍 门月华 初明 张春雷. 黄连素软膏对特应性皮炎样小鼠皮肤炎症及菌群的影响作用[J]. 中华皮肤科杂志, 2026, 59(4): 353-360. |
| [13] | 中国整形美容协会皮肤美容分会 中国非公立医疗机构协会皮肤专业委员会. [开放获取] 医用重组人源化胶原蛋白在面部年轻化中的应用专家建议(2026版)[J]. 中华皮肤科杂志, 2026, 59(4): 320-326. |
| [14] | 中华医学会皮肤性病学分会儿童学组 中国康复医学会皮肤病康复专业委员会儿童皮肤病学组 中国医师协会皮肤科医师分会儿童皮肤病学组 中国中药协会儿童健康与药物研究专业委员会外治疗法学组 中国医师协会儿科分会皮肤病学组 . 中国儿童斑秃诊断和治疗专家共识(2026版)[J]. 中华皮肤科杂志, 2026, 59(4): 291-303. |
| [15] | 曾莞欣 文翔. 增生性瘢痕的光电治疗进展[J]. 中华皮肤科杂志, 2026, 59(3): 269-273. |
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