中华皮肤科杂志 ›› 2022, Vol. 55 ›› Issue (6): 545-548.doi: 10.35541/cjd.20200248

• 综述 • 上一篇    下一篇

天疱疮合并单纯疱疹病毒感染的研究进展

张寒梅    冯素英   

  1. 中国医学科学院、北京协和医学院皮肤病医院皮肤科，南京  210042
  • 收稿日期:2020-03-12 修回日期:2020-06-15 发布日期:2022-06-02
  • 通讯作者: 冯素英 E-mail:fengsuying2015@163.com
  • 基金资助:
    中国医学科学院医学与健康科技创新工程项目（CIFMS-2017-I2M-1-017）

Pemphigus complicated by herpes simplex virus infection

Zhang Hanmei, Feng Suying   

  1. Department of Dermatology, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2020-03-12 Revised:2020-06-15 Published:2022-06-02
  • Contact: Feng Suying E-mail:fengsuying2015@163.com
  • Supported by:
    CAMS Innovation Fund for Medical Sciences（CIFMS-2017-I2M-1-017）

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摘要： 【摘要】 病毒感染是天疱疮常见的并发症之一，近年来天疱疮合并病毒感染的相关研究主要集中于单纯疱疹病毒（HSV）。有研究显示，HSV感染会对天疱疮患者的病程、治疗效果甚至皮损形态等产生影响。但由于现有研究在样本量、检验方式等方面存在较多差异，故HSV在天疱疮患者中的发生率及对天疱疮临床特征的总结在各研究结果中差异较大。本文就天疱疮合并HSV感染的发生率及临床特征做一综述，以提高临床医生对该病的认识并为诊治提供依据。

关键词: 天疱疮, 疱疹病毒1型, 人, 疱疹病毒2型, 人, 疾病特征

Abstract: 【Abstract】 Virus infection is one of the common complications of pemphigus. In recent years, related studies on pemphigus complicated by virus infection have mainly focused on the herpes simplex virus （HSV）. Studies have shown that HSV infection can affect the course of disease, therapeutic effect, and even the morphology of skin lesions in patients with pemphigus. However, due to large differences in sample sizes and test methods, the incidence and clinical characteristics of HSV infection in patients with pemphigus markedly differ among different studies. This review summarizes the incidence and clinical characteristics of pemphigus complicated by HSV infection, aiming to improve clinicians′ understanding of the disease and provide a basis for its diagnosis and treatment.

Key words: Pemphigus, Herpesvirus 1, human, Herpesvirus 2, human, Disease attributes