中华皮肤科杂志 ›› 2010, Vol. 43 ›› Issue (4): 287-288.

• 病例报告 • 上一篇    下一篇

银屑病并发砷角化症、Bowen病及多发性鳞状细胞癌一例

魏瑾1,杨振海2,李久宏3,李波4,张丽5,管秀好5,高兴华5   

  1. 1. 中国医科大学
    2. 沈阳市中国医科大学附属第一医院皮肤科
    3. 沈阳中国医科大学附属第一医院皮肤科
    4. 沈阳中国医科大学第一临床学院
    5. 沈阳 中国医科大学附属第一医院皮肤科
  • 收稿日期:2009-07-20 修回日期:2009-10-19 出版日期:2010-04-15 发布日期:2010-04-07
  • 通讯作者: 魏瑾 E-mail:branchyberry@yahoo.com.cn

Arsenic keratosis，Bowen’s disease and multiple squamous cell carcinoma in a patient with psoriasis: a case report

  • Received:2009-07-20 Revised:2009-10-19 Online:2010-04-15 Published:2010-04-07
  • Contact: Jin WEI E-mail:branchyberry@yahoo.com.cn

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摘要：

[摘 要] 报道1例银屑病并发砷角化症、鲍温病及多发性鳞癌。患者男，55岁，患寻常型银屑病25年，口服砷制剂治疗8年，出现右大腿肿物3年，周身多处角化性丘疹2年，加重5个月，手术切除10处皮损组织后病理检查显示，1处皮损证实为鲍温病，4处皮损为鳞癌，其余符合砷角化症。值得临床医生警惕含砷制剂的远期效应及避免不规范治疗。

关键词: 银屑病, 砷角化症, 鲍温病, 鳞癌

Abstract:

[Abstract] A case of arsenical keratosis ，Bowen’s disease and multiply squamous cell carcinoma in a patient with psoriasis is reported. A 55-year-old male with a 25-year-history of psoriasis has an arsenic intake history for treatment of 8 years, presented with a history of tumor on the right leg for 3 years, and multiply keratotic papules on the trunk and extremities for 2 years, aggravating for 5 months. Surgical therapy on 10 skin lesions was performed. Histopathology of the skin lesions showed, of which, one lesion as Bowen’s disease, four as squamous cell carcinoma, all else as arsenical keratosis. It’s worth clinicians being aware of the long-term effect of arsenic containing medicines and avoiding unregulated use of such remedies.

Key words: Psoriasis, Arsenical keratosis, Bowen's disease, Squamous cell carcinoma