脂肪干细胞基质胶临床应用进展

doi:10.35541/cjd.20240300

中华皮肤科杂志 ›› 2025, e20240300.doi: 10.35541/cjd.20240300

脂肪干细胞基质胶临床应用进展

袁梦莎¹ 赵涛¹ 刘玲²

¹空军军医大学西京皮肤医院，西安 710032；²空军军医大学唐都医院皮肤科，西安 710038

收稿日期:2024-06-04 修回日期:2024-09-11 发布日期:2025-02-08
通讯作者: 刘玲 E-mail:vanilla@fmmu.edu.cn
基金资助:
空军军医大学西京医院交叉医学研究专项（XJZT24JC27）

Clinical application of stromal vascular fraction gel

Yuan Mengsha¹, Zhao Tao¹, Liu Ling²

¹Department of Dermatology, Xijing Hospital, Air Force Medical University, Xi′an 710032, China; ²Department of Dermatology, Tangdu Hospital, Air Force Medical University, Xi′an 710038, China

Received:2024-06-04 Revised:2024-09-11 Published:2025-02-08
Contact: Liu Ling E-mail:vanilla@fmmu.edu.cn
Supported by:
Interdisciplinary Research Project of Xijing Hospital（XJZT24JC27）

摘要/Abstract

摘要： 【摘要】脂肪干细胞基质胶是采用物理方法将脂肪组织机械切割离心，去除成熟脂肪细胞和油滴后获得的高活性物质，因其保留了脂肪干细胞、细胞外基质和浓缩血管基质片段，且可低温储存，近年来在填充、色素异常改善、瘢痕、创面修复等领域广泛应用。本文综述脂肪干细胞基质胶在烧伤、整形、皮肤科应用的现状及前景。

关键词: 干细胞, 真皮填充剂, 脂肪干细胞基质胶, 脂肪干细胞, 色素异常, 创面愈合

Abstract: 【Abstract】 Stromal vascular fraction gel （SVF-gel） is a highly active substance obtained by mechanically cutting and centrifugation of adipose tissues, with mature fat cells and oil droplets removed in the process. Due to the reserve of adipose-derived stem cells, extracellular matrix, and concentrated stromal vascular fractions, as well as the capability for low-temperature storage, SVF-gel has been widely used in various fields such as filling, improvement of pigmentation abnormalities, scar treatment, and wound repair in recent years. This review summarizes the current status and prospects of the application of SVF-gel in burn care, plastic surgery, and dermatology.

Key words: Stem cells, Dermal fillers, Stromal vascular fraction gel, Adipose-derived stem cells, Pigmentation disorder, Wound healing

袁梦莎赵涛刘玲. 脂肪干细胞基质胶临床应用进展[J]. 中华皮肤科杂志, 2025,e20240300. doi:10.35541/cjd.20240300

Yuan Mengsha, Zhao Tao, Liu Ling. Clinical application of stromal vascular fraction gel[J]. Chinese Journal of Dermatology,2025,e20240300. doi:10.35541/cjd.20240300

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脂肪干细胞基质胶临床应用进展

Clinical application of stromal vascular fraction gel

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